Drug with anti-osteoporosis effect

Abstract

The invention discloses a drug with an anti-osteoporosis effect. The drug comprises one, two or more than two of the following components: a compound 1: 5,7,4'-trihydroxyl-3'-methoxy-6,8-dimethyl dihydrhomoisoflavonoid, a compound 2: dihydrhomoisoflavonoid, a compound 3: 6-formyl isoophiopogonone B, a compound 4: 6--formyl isoophiopogonone A, a compound 5: methyl isoophiopogonone B, a compound 6: 5,7,4'-trihydroxyl-6-methyl homoisoflavonoid, a compound 7: 5,7,4'-trihydroxyl-6-methyl dihydrohomoisoflavonoid and a compound 8: methyl dihydrisoophiopogonone A. The drug with the anti-osteoporosis effect provided by the invention has an obvious treatment effect in lowering bone mineral loss of an osteoporosis rat and bone biomechanical strength without an obvious toxic and side effect. The compound source is extensive, not only can be obtained by extracting from the plant, but also can be prepared by adopting an artificial synthesis method.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to ingredients for treating and preventing osteoporosis. technical background [0002] As the world population continues to age, osteoporosis will become a massive global health problem. According to a European Union report on osteoporosis, the lifetime risk of osteoporotic fractures in the world can be as high as 40% for women and 13% for men; the number of hip fractures will increase from 1.7 million in 1990 by 2050 Hip fractures will rise sharply in Asia, which has a rapidly growing and aging population, to 6.3 million. This will inevitably result in a substantial increase in global health care costs. Osteoporosis has the greatest impact on the health of older women and is a major women's health concern. One third of women have a lifetime risk of osteoporotic fractures. Common osteoporotic fractures include hip fractures and spinal fractures, and often cause secondary comp...

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