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Pharmaceutical composition for treating osteoporosis and preparing method thereof

A technology for osteoporosis and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the problems of reduced patient acceptability and high side effects, etc.

Inactive Publication Date: 2016-04-06
ZIBO VOCATIONAL INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] For the treatment of osteoporosis, estrogen, parathyroid hormone, calcium supplements, bisphosphonates, etc. are commonly used at present, but their high side effects greatly reduce the acceptability of patients

Method used

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  • Pharmaceutical composition for treating osteoporosis and preparing method thereof
  • Pharmaceutical composition for treating osteoporosis and preparing method thereof
  • Pharmaceutical composition for treating osteoporosis and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The preparation of embodiment 1 pharmaceutical composition A1

[0018] Pharmaceutical composition A1, made from the following raw materials:

[0019] 90g hand ginseng, 90g western Sichuan chrysanthemum, 80g ginseng, 80g Digupi, 80g broad tendon vine, 50g yak bone, 30g mother-of-pearl, 50g Anemarrhena. Its preparation method is as follows:

[0020] Crush the mother-of-pearl into fine powder, add 4000ml of water to the remaining medicinal materials and decoct twice, combine them and concentrate until dry, add mother-of-pearl fine powder, and mix well to obtain the product.

Embodiment 2

[0021] The preparation of embodiment 2 pharmaceutical composition A2

[0022] Pharmaceutical composition A2, made from the following raw materials:

[0023] 50g of hand ginseng, 60g of western Sichuan chrysanthemum, 40g of ginseng, 60g of Digupi, 60g of broad tendon vine, 30g of yak bone, 40g of Anemarrhena, 20g of mother of pearl;

[0024] Its preparation method is with embodiment 1.

Embodiment 3

[0025] The preparation of embodiment 3 pharmaceutical composition A3

[0026] Pharmaceutical composition A3, made from the following raw materials:

[0027] 160g of hand ginseng, 120g of western Sichuan chrysanthemum, 160g of ginseng, 120g of Digupi, 100g of wide tendon rattan, 70g of yak bone, 80g of Anemarrhena, 60g of mother of pearl;

[0028] Its preparation method is with embodiment 1.

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Abstract

The invention discloses a pharmaceutical composition for treating osteoporosis and a preparing method thereof. The pharmaceutical composition is prepared from conic gymnadenia rhizome, west szechwan pyrethrum, ginseng, cortex lycii radicis, tinospora sinensis stem, yak bone, rhizoma anemarrhenae and concha margaritifera. The preparing method comprises the steps of smashing concha margaritifera into fine powder and conducting heat extraction on other medicinal materials, combining extracting solutions and conducting concentration to dry, adding the concha margaritifera fine powder, and conducting even mixing. It is found through pharmacological research that aqueous extracts and alcohol extracts, especially acidity alcohol extracts, of the pharmaceutical composition have certain curative effect on the bone mineral density and bone biomechanics index of the thighbone and tibia of an osteoporosis model rat, the indexes of calcium and BGP in serum, and the index of HOP in urine, and the pharmaceutical composition can be used for treating osteoporosis, especially osteoporosis caused by estrogen deficiency.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating osteoporosis and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Osteoporosis, or osteoporosis, is a disease caused by a variety of factors, characterized by bone pain and susceptibility to fracture. It is closely related to factors such as age, hormones, genetics, nutritional intake, and lifestyle. Its pathogenesis is mainly that the activity of osteoclasts is enhanced, while the activity of osteoblasts is inhibited, and the rate of bone resorption exceeds the rate of formation. Causes the reduction of organic and inorganic matter in bone tissue. According to reports, about 70 million people over the age of 50 in China suffer from osteoporosis, and the incidence rate of women exceeds 30%. As the aging population continues to increase, osteoporosis will become an increasingly serious public health threat. [0003] For the treat...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P19/10A61K35/618A61K35/32
CPCA61K35/32A61K35/618A61K36/258A61K36/28A61K36/59A61K36/815A61K36/8964A61K36/898A61K2236/331A61K2236/333A61K2300/00
Inventor 贾雷
Owner ZIBO VOCATIONAL INST
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