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Medicine with effects of producing marrow and strengthening bone for treating alcoholic osteoporosis and preparation method thereof

An osteoporosis and alcoholic technology, applied in the field of traditional Chinese medicine, can solve problems such as increasing patient pain, reducing quality of life, and interfering with bone formation and absorption

Active Publication Date: 2019-01-01
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Glucocorticoids interfere with the formation and resorption of bone through various mechanisms, thereby causing an increase in the incidence of osteoporosis and fractures, increasing the suffering of patients, and reducing the quality of life

Method used

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  • Medicine with effects of producing marrow and strengthening bone for treating alcoholic osteoporosis and preparation method thereof
  • Medicine with effects of producing marrow and strengthening bone for treating alcoholic osteoporosis and preparation method thereof
  • Medicine with effects of producing marrow and strengthening bone for treating alcoholic osteoporosis and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0292] Prescription: Astragalus 500g, Atractylodes macrocephala 400g, angelica 400g, kudzu root 400g, salvia miltiorrhiza 400g, turmeric 400g, achyranthes bidentata 300g, rehmannia glutinosa 200g, earthworm 200g, antler glue 200g, tortoise shell 200g, keel 200g, oyster 200g, the raw marrow and health Bone Capsules (formerly known as Jianguling Capsules) are prepared as follows:

[0293] Preparation:

[0294] (1) Take astragalus, Atractylodes, Angelica, Gegen, crushed into coarse powder, add 10 times 85 % ethanol to heating back and extract 2 times, 2h each time, combine extraction solution, filtering, concentration of filtrate, ethanol R1; ethanol; ethanol; ethanol; The medicinal residues R2 after reflux extraction are kept for subsequent use;

[0295] (2) Combine Salvia miltiorrhiza, Curcuma, Achyranthes bidentata, Rehmannia glutinosa and the medicinal residue R2 obtained in step (1), add 10 times the amount of water to decoct and extract twice, 2 hours each time, combine th...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and relates to a medicine with effects of producing marrow and strengthening bone for treating alcoholic osteoporosis and a preparation method thereof. The medicine is prepared from the following raw materials in parts by weight: 2 to 8 parts of radix astragali seu hedysari, 2 to 8 parts of bighead atractylodes rhizome, 2 to 8 parts of Chinese angelica, 2 to 8 parts of radix puerariae, 2 to 8 parts of radix salviae miltiorrhizae, 2 to 8 parts of radix curcumae, 2 to 8 parts of radix achyranthis bidentatae, 1 to 4 parts of radix rehmanniae preparata, 1 to 4 parts of lumbricus, 1 to 4 parts of deer-horn glue, 1 to 4 parts of turtle shell, 1 to 4 parts of dragon bone, and 1 to 4 parts of concha ostreae. The medicine with effects of producing marrow and strengthening bone has the advantages that the bone density BMC is increased, and the content of bone mineral (BMD) is increased; various indexes of biological and mechanical properties of bone, such as maximum load, extreme strength, maximum flexibility, and elastic modulus, can be obviously improved, and the bone hardness and bone elasticity are improved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a marrow-growing and bone-strengthening medicine for treating alcoholic osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis is a systemic bone disease in which bone density and bone quality decrease due to various reasons, bone microstructure is destroyed, bone fragility increases, and fractures are prone to occur. Osteoporosis is divided into primary and secondary two categories. Primary osteoporosis is divided into three types: postmenopausal osteoporosis (type I), senile osteoporosis (type II) and idiopathic osteoporosis (including juvenile type). Postmenopausal osteoporosis generally occurs in women within 5 to 10 years after menopause; senile osteoporosis generally refers to the osteoporosis that occurs in the elderly after the age of 70; idiopathic osteoporosis mainly occurs in adolescents, and the etiology is s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P19/10G01N30/02A61K35/62A61K35/618A61K35/586A61K35/32A61K35/02
CPCA61K35/02A61K35/32A61K35/586A61K35/618A61K35/62A61K36/21A61K36/232A61K36/284A61K36/481A61K36/488A61K36/537A61K36/804A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61P19/10G01N30/02A61K2300/00
Inventor 任树军邢国利王墉琦任明辉谭福柱
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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