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Formula and production technology of health-care food and medicine composed of fructose and radix astragali seu hedysari and used for preventing and treating muscle atrophy

A production process and muscle atrophy technology, which can be used in pharmaceutical formulations, the function of food ingredients, and food ingredients containing natural extracts, etc. It can solve problems such as inability to function in the body and failure of fat to be oxidized and decomposed.

Inactive Publication Date: 2018-10-26
GUANGDONG SPRINGYOUNG BIOTECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Total cholesterol and triglycerides in serum are indicators involved in fat metabolism, and the content of these two in the model group is relatively high, indicating that fat has not been oxidized and decomposed in time, and cannot contribute to the function of the body.

Method used

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  • Formula and production technology of health-care food and medicine composed of fructose and radix astragali seu hedysari and used for preventing and treating muscle atrophy

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Experimental program
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Effect test

Embodiment 1

[0017] In order to evaluate the effect of Astragalus fructose preparation on bone biomechanics and muscle, we used D-galactose to establish an aging mouse model with muscle damage, and prepared it according to the formula and process of fructose Astragalus Oral Liquid as an experimental drug. The concentration of fructose is 12%, the concentration of Astragalus membranaceus calculated as crude drug is 50%, and the dosage of mice is administrated by intragastric administration at 0.1ml / 10g; the specific experimental method is to select 100 clean-grade white Kunming mice, male, weighing 20g-30g , Raised in a normal-grade animal breeding room, the animals were acclimatized to the environment for 1 week before the experiment, fed with common pellet feed, and drank clean tap water, 10 animals per cage. The experiment was divided into (1) normal control group: the mice were given normal saline by intragastric administration of 0.1ml per 10g of body weight. (2) D-galactose model grou...

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PUM

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Abstract

The invention provides a formula and production technology of one group of health-care foods and medicines composed of fructose and radix astragali seu hedysari and used for preventing and treating muscle atrophy. Osteoporosis and the muscle atrophy are common symptoms occurred along with human body aging; commonly, legs become old before people get old; the invention discloses one group of the health-care foods and medicines composed of the fructose and the radix astragali seu hedysari and used for preventing and treating the muscle atrophy, and one group of the health-care foods and medicines comprises 7 preparations with different preparation forms and is characterized in that a composition is composed of 12 percent of the fructose and 50 percent of the radix astragali seu hedysari; thecompositions have very good prevention and treatment effects on muscle fatigues, muscle loss, the muscle atrophy and bone biomechanics performance degradation caused by excessive exercise, damages, diseases or ageing; the fructose in the formula can be used for enabling muscle to obtain energy supplementation needed by lives; the fructose can directly enter the muscle, without the need of an insulin way, and is directly transformed into muscle glycogen; metabolic disorders caused by the fact that muscle tissue cells are lack of energy are supplemented in time; meanwhile, the radix astragali seu hedysari can be used for promoting the repairing of muscle tissues and the synthesis of protein, so that the muscle is stronger and more powerful; the fructose and the radix astragali seu hedysariare combined and commonly play a role of strengthening bones and the muscle and preventing and controlling the muscle atrophy.

Description

technical field [0001] The invention belongs to the technical field of health food and medicine production, and specifically relates to a group of pharmaceutical compositions composed of fructose and astragalus, which can strengthen muscles and prevent muscle atrophy. Background technique [0002] Skeletal muscle atrophy (referred to as muscle atrophy) mainly refers to the reduction of skeletal muscle mass and muscle function. The occurrence of muscle atrophy is a comprehensive manifestation of the negative balance of protein degradation and synthesis in skeletal muscle. The influencing factors include changes in related hormones and tissue levels of reactive oxygen species. changes and apoptosis. The common causes of muscle atrophy include long-term malnutrition, generalized or partial limb movement reduction or loss, and denervation. "A person's legs get old first" refers to the occurrence of human aging with the prolongation of age. In the process of aging, it starts wit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K36/82A61P21/00A23L33/105A23L33/125A23L2/38A23F3/34A61K31/7004A61K33/14
CPCA61P21/00A23F3/34A23L2/38A23L33/105A23L33/125A61K31/7004A61K33/14A61K36/481A61K36/82A23V2002/00A61K2236/333A61K2236/331A61K2236/51A61K2236/39A61K2236/53A61K2300/00A23V2250/21A23V2250/606A23V2200/316
Inventor 吴铁徐伟雄崔燎许碧莲梁美婷
Owner GUANGDONG SPRINGYOUNG BIOTECH
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