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Eye drops for anti-eye fatigue and preparation method thereof

A technology for eye drops and eye fatigue, which is applied in the field of medicine and health, can solve the problems of increasing toxic and side effects, great differences in effects, and discomfort of patients, and achieve the effects of relieving ciliary muscle fatigue, overcoming single performance, and relieving vasospasm

Active Publication Date: 2017-09-29
宁夏瑞视眼科研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing ophthalmic eye drops for the treatment of eye fatigue and the prevention and treatment of myopia in adolescents have many drug efficacy defects: the one is that the property of medicine is single, and the effect is limited, often only A drug only works on one phenomenon, with very limited effects and efficacy
From the analysis of the mechanism of ciliary muscle fatigue and spasm, a single drug only solves one aspect of the problem, and does not intervene in the whole process and multiple links of the problem. Therefore, the degree of intervention of a single drug is limited, and the effect of eliminating fatigue varies. very big
Second, long-term use, students are not easy to adhere to
For students and teenagers, if the ciliary muscle fatigue cannot be relieved quickly, it will bring inconvenience to study and life
Third, the drug is highly toxic
In order to enhance the action and effect of medicines, it is often necessary to use several medicines at the same time, which inadvertently increases the toxic and side effects of medicines, and often causes discomfort to patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0038] Wang Dan, female, 9 years old. Before the refractive examination in June 2010, the right eye was 0.8 and the left eye was 0.6. The result of dilated retinoscopy optometry is: right eye -0.5Ds combined -0.5Dc axial 180, visual acuity 5.0 (logarithmic); left eye -0.75 Ds combined -0.5Dc axial 180, visual acuity 5.0 (logarithmic). Taking drug treatment and follow-up, the uncorrected visual acuity in the first month was 1.2- in the right eye and 1.0+ in the left eye. The second month's examination: right eye 1.2, left eye 1.2.

[0039] Main measures: Start treatment when the vision is lower than 1.2, or when it falls below 1.0. After half a year to 2 years, the visual acuity test is still stable at 1.2, and the dilation test does not increase the degree.

experiment example 2

[0041] Zhao Xiaofang, female, 12 years old. Before the refraction examination in February 2010, the right eye was 0.2 and the left eye was 0.3. The result of dilated retinoscopy optometry is: right eye -2.5Ds combined -0.5Dc axial 180, visual acuity 5.0 (logarithmic); left eye -275 Ds combined -0.5Dc axial 180, visual acuity 5.0 (logarithmic). Take focus glasses plus drug therapy plus follow-up. The corrected visual acuity in the first month re-examination was: 1.2 in the right eye and 1.2 in the left eye; in the second month: 1.2 in the right eye and 1.2 in the left eye. After one year, the visual acuity remained stable at 1.2+-. After tracking for 3 years, the degree did not increase again.

experiment example 3

[0043] Ma Xiaodong, male, 15 years old. Refractive examination in May 2012: Right eye -6.5Ds combined -2.5Dc axial 180, visual acuity reached 5.0 (logarithmic); left eye -6.00 Ds combined -2.5Dc axial 180, visual acuity reached 5.0 (logarithmic) . Take focus glasses plus drug therapy plus follow-up. Corrected visual acuity in the first month: right eye 1.2, left eye 1.2; second month check: right eye 1.2+, left eye 1.2+, visual acuity reached 1.5 after three months, felt uncomfortable, mydriasis check left and right diopters Reduced by -100Ds, after one year, the vision is still stable at 1.2+-. After tracking for 2 years, the degree did not increase again.

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PUM

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Abstract

The invention discloses eye drops for resisting asthenopia. The eye drops comprise the following components: amiotide eye drops, inosine injection, adenosine disodium triphosphate injection, racanisodamine injection, vitamin B6 injection, taurine eye drops and an assistant for eyes, wherein the assistant for eyes is at least one of injection water or an isoosmotic adjusting agent; the isoosmotic adjusting agent is at least one of a sodium chloride physiological saline, glucose injection, sorbitol eye drops, borate saline buffer, mannitol injection or polyethylene glycol eye drops. The invention also discloses a preparation method of the eye drops for resisting asthenopia. The eye drops have the advantages that: 1, the overall efficacy of a compound preparation is obviously superior to a single drug effect; 2, the eye drops play roles in the whole process of the disease, the dose is reduced, and the side effect is reduced; 3, various medicines work in coordination with each other, are complementary in efficacy, and are taken as preconditions for playing roles; 4, the eye drops are obvious in pharmacological effect, applicable and convenient, and convenient to carry.

Description

Technical field: [0001] The invention belongs to the technical field of medicine and health, and relates to an ophthalmic eye drop applied to the treatment of eye fatigue caused by any reason and the prevention, control and treatment of juvenile myopia and a preparation method thereof, in particular to an anti-eye fatigue eye drop Eye drops and methods for their preparation. Background technique: [0002] For modern people who often stare at the display screen, or high-intensity work leads to eye fatigue and the myopia of teenagers is getting more and more serious. In addition to relaxing the eyes or correcting vision, there is also the application of medication to the eyes to relieve visual fatigue and prevent myopia. [0003] Existing ophthalmic eye drops for the treatment of eye fatigue and the prevention and treatment of juvenile myopia have many drug efficacy defects: the one is that the property of medicine is single, and the effect is limited. limited. From the ana...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/55A61K9/08A61P27/02A61P27/10A61K35/44A61K31/7076A61K31/46A61K31/4415A61K31/185
Inventor 李绍君张秀平梁静
Owner 宁夏瑞视眼科研究所
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