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45 results about "Mannitol Injection" patented technology

20% Mannitol Injection USP is a sterile, nonpyrogenic solution of Mannitol USP in a single dose container for intravenous administration. It contains no antimicrobial agents. Mannitol is a 6-carbon sugar alcohol prepared commercially by the reduction of dextrose. Although virtually inert ...

Thermal insulation device for water-bath heating and dissolving of mannitol

ActiveCN103920401AEvenly heatedSolution is not easy to dissolveMixer accessoriesDissolvingTemperature controlInsulation layer
The invention discloses a thermal insulation device for water-bath heating and dissolving of mannitol. The thermal insulation device comprises a heating box and a thermal insulation box, wherein a thermal-protective coating is arranged between the heating box and the thermal insulation box; the heating box and the thermal insulation box comprise box bodies and box covers; box body walls and the box covers structurally comprise housings, thermal insulation layers and water-resisting layers; a heating device is arranged above the thermal insulation layer inside each box body and is connected with a temperature controller; a filter net is arranged inside each box body; a vertical lead rail is also arranged at the inner side of each water-resisting layer; a bump matched with the corresponding lead rail is arranged on the edge of each filter net; a filter net crank is arranged on the outer side of each box body, and controls the corresponding filter net to slide up and down along the corresponding lead rail through a cam device; a heat-conducting coil is also arranged on the bottom of the thermal insulation box; a water inlet and a water outlet of the heat-conducting coil are formed inside the heating box; a miniature temperature control electric pump is arranged at the water inlet section of the heat-conducting coil inside the thermal insulation box, and connected with the temperature controller. The device can be used for heating and constantly keeping warm, the problems that mannitol injection is not easy to inject at low temperature or high temperature are solved, and the thermal insulation device has an energy-saving effect, and is convenient to use, low in manufacturing and use costs, and convenient to popularize and use.
Owner:滨州医学院附属医院

Intestinal flora reconstruction kit and application thereof

ActiveCN108891725AEasy to useEasy to takeDigestive systemUnknown materialsIntestinal structurePolyethylene glycol electrolyte powder
The invention discloses an intestinal flora reconstruction kit and application thereof. The kit comprises a kit body, which comprises a plurality of chambers opened sequentially and regularly, whereinthe chambers are an n chamber to an n+x chamber according to the opening sequence, the opening time interval between the adjacent chambers in an n+1 chamber to the n+x chamber is setas 4-12 hours; the nchamber contains compound polyethylene glycol electrolyte powder or mannitol injection; the n+1 chamber contains microecological preparation agents with group A and B; ann+2 chamber contains the microecological preparation agents with group B and C; an n+3 chamber to an n+33 chamber contain the microecological preparation agent with group A or B; and an n+34 chamber to the n+x chamber contains the microecological preparation agent with group B. Taking different preparation agents by washing intestines and taking the agents in different sequences is conducive to the rapid establishment of the intestinal flora. The invention further discloses an application of the kit in the reconstruction of diabetic intestinal flora, the flora reconstruction is conducive to regulating the blood glucose of patients, so that the reconstruction of intestinal flora is feasible in regulating the blood glucose of the diabetic patients.
Owner:HEBEI UNIVERSITY

Production and preparation process capable of lowering mannitol injection crystallization

The invention relates to a production and preparation process capable of lowering mannitol injection crystallization. The production and preparation process is characterized in that material preparation is operated under Grade-B environment conditions under a background Grade-C, and raw materials are enabled to pass a 200-mesh screen, namely a screen of 75um+/-4.1um; a super filter element terminal of 0.1um is adopted for filtering; a preparation method of a PH value adjuster includes: weighing 180ml of concentrated hydrochloric acid, adding water for injection to 1000ml, shaking well, and using a filter membrane of 0.1um to perform suction filtering to obtain a hydrochloric acid adjuster of 2mol/L; a PH value adjusting method includes: weighing 2mol/L hydrochloric acid in a needed amount, pouring into a clean measuring cup, linearly adding into a diluting tank while stirring, and stirring well; 90-100 DEG C is determined as using temperature of the water for injection, number of intensive washing times is 10 times of flushing, and water pressure for flushing each time is not lower than 0.15Mpa. By the production and preparation process, proportion of mannitol crystallization during selling is lowered, and high-quality products are provided for clinical medication.
Owner:JIANGXI KELUN MEDICINE IND

Drug composition for treating radiation-induced oral mucositis and application thereof

The invention relates to a drug composition for treating radiation-induced oral mucositis and application thereof. The drug composition is prepared from the following crude drugs: 20% of mannitol injection, lidocaine hydrochloride injection, vitamin B12 injection, dexamethasone sodium phosphate for injection and raceanisodamine hydrochloride injection. The invention also provides the application of the drug composition in preparation of a drug for treating radiation-induced acute oral mucositis. The drug composition and the application thereof have the advantages that (1) compared with the traditional drug for clinically treating the radiation-induced oral mucositis, the injury degree of the radiation-induced oral mucositis can be obviously relieved, the symptom relieving time can be obviously shortened, and the survival quality in the radiotherapy process of a patient can be improved; (2) the preparation process of a formula is simple, special process and conditions are not needed, the drugs needed by composition of the formula are clinically-common drugs respectively, the drug source is sufficient, the price is low, the preparation is convenient, the storage and transportation are convenient, the economic burden of the patient is low and the drug composition can be well applied on clinic.
Owner:JINSHAN HOSPITAL FUDAN UNIV

Fast detection method of intermediate mannitol content of compound mannitol injection

The invention discloses a fast detection method of the intermediate mannitol content of a compound mannitol injection. Firstly, the optical rotation alpha 1 of glucose in the compound mannitol injection is measured under the conditions of using sodium lamp D rays with the wavelength being 589 nm as a light source and the measuring temperature being 20+/-0.5 DEG C; then, the total optical rotationalpha 2 of glucose and mannitol in the compound mannitol injection is measured under the same conditions; the mannitol content in the compound mannitol injection is calculated by using a differentialrotation method. The detection method provided by the invention has the advantages that the interference of the glucose on the mannitol detection result is avoided; the differential rotation method isused, so that the content of the mannitol can be accurately obtained; ammonium molybdate is used as a rotation increasing agent, so that the optical rotation performance of a solution to be tested can be obviously increased, and the detection result is more accurate. The detection method has the advantages of strong specificity, high accuracy, good middle precision and good repeatability. The method has the advantages that the practicability is high; the detection environment temperature and the sample standing time do not have obvious influence on the detection result.
Owner:SICHUAN KELUN PHARMA CO LTD

Device for preventing mannitol injection from crystallizing

The invention relates to a device for preventing mannitol injection from crystallizing. The device comprises a mannitol thermotank, pin caps, and hinge movable rods, sliding groove rods are formed inthe two sides of the mannitol thermotank, clamping grooves are connected to the inner sides of the sliding groove rods, a bearing frame is mounted on the inner sides of the clamping grooves, the two sides of the outer portion of the mannitol thermotank are connected with closing doors, hinge columns are arranged on one sides of the interiors of the closing doors, a ventilation frame is connected with the top end of the interior of the mannitol thermotank, the top end of the ventilation frame is provided with a top cover frame, the top end of the bearing frame is provided with a mannitol bottleplacing frame, and the bottom end of the ventilation frame is connected with an active carbon layer frame. The device has the beneficial effects that a user can push the active carbon layer frame todrive a sliding block to do lifting motion along the position between the sliding groove rods, the active carbon layer frame can be effectively lifted to be isolated between storage frames, peculiar smell between walls of the mannitol thermotank can be absorbed between layers of the active carbon layer frame, and the peculiar smell of the mannitol thermotank can be purified.
Owner:马丽芳

A production and preparation process for reducing crystallization of mannitol injection liquid

The invention relates to a production and preparation process capable of lowering mannitol injection crystallization. The production and preparation process is characterized in that material preparation is operated under Grade-B environment conditions under a background Grade-C, and raw materials are enabled to pass a 200-mesh screen, namely a screen of 75um+ / -4.1um; a super filter element terminal of 0.1um is adopted for filtering; a preparation method of a PH value adjuster includes: weighing 180ml of concentrated hydrochloric acid, adding water for injection to 1000ml, shaking well, and using a filter membrane of 0.1um to perform suction filtering to obtain a hydrochloric acid adjuster of 2mol / L; a PH value adjusting method includes: weighing 2mol / L hydrochloric acid in a needed amount, pouring into a clean measuring cup, linearly adding into a diluting tank while stirring, and stirring well; 90-100 DEG C is determined as using temperature of the water for injection, number of intensive washing times is 10 times of flushing, and water pressure for flushing each time is not lower than 0.15Mpa. By the production and preparation process, proportion of mannitol crystallization during selling is lowered, and high-quality products are provided for clinical medication.
Owner:JIANGXI KELUN MEDICINE IND
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