79results about How to "Lower intracranial pressure" patented technology

In one embodiment, the invention provides a medical method for treating a person and comprises repeatedly compressing the person's chest. While repeatedly compressing the person's chest, the method further includes repeatedly delivering a positive pressure breath to the person and extracting respiratory gases from the person's airway using a vacuum following the positive pressure breath to create an intrathoracic vacuum to lower pressures in the thorax and to enhance blood flow back to the heart.

A method for increasing circulation and providing oxygen to a patient in cardiac arrest includes the step of coupling an interface to the patient's airway, the interface providing access to the patient's respiratory system. A valve system is operably attached to the interface. Oxygen is delivered through the interface a rate of between about 1.0 to about 10.0 L / min to provide a continuous supply of oxygen to the patient. While supplying the oxygen, a body structure of the patient is manipulated to increase the magnitude and duration of the patient's negative intrathoracic pressure. During the manipulation, the valve system prevents additional respiratory gases from entering the lungs until a negative intrathoracic pressure level in the range from about −1 cm H2O to about −15 cm H2O, the valve system assisting in increasing the magnitude and duration of negative intrathoracic pressure thereby enhancing the amount of blood flow in the heart and lungs and lowering intracranial pressure, therein further increasing blood flow to the brain.

In one embodiment, the invention provides a device for decreasing intracranial or intraocular pressures. The device comprises a housing having an inlet opening and an outlet opening that is adapted to be interfaced with a person's airway. The device further includes a valve system that is operable to regulate respiratory gas flows through the housing and into the person's lungs during spontaneous or artificial inspiration. The valve system assists in lowering intrathoracic pressures during each inspiration to repetitively lower pressures in the venous blood vessels that transport blood out of the head to thereby reduce intracranial or intraocular pressures.

In one embodiment, the invention provides a device for decreasing intracranial or intraocular pressures. The device comprises a housing having an inlet opening and an outlet opening that is adapted to be interfaced with a person's airway. The device further includes a valve system that is operable to regulate respiratory gas flows through the housing and into the person's lungs during spontaneous or artificial inspiration. The valve system assists in lowering intrathoracic pressures during each inspiration to repetitively lower pressures in the venous blood vessels that transport blood out of the head to thereby reduce intracranial or intraocular pressures.

A method for increasing circulation and providing oxygen to a patient in cardiac arrest includes the step of coupling an interface to the patient's airway, the interface providing access to the patient's respiratory system. A valve system is operably attached to the interface. Oxygen is delivered through the interface a rate of between about 1.0 to about 10.0 L / min to provide a continuous supply of oxygen to the patient. While supplying the oxygen, a body structure of the patient is manipulated to increase the magnitude and duration of the patient's negative intrathoracic pressure. During the manipulation, the valve system prevents additional respiratory gases from entering the lungs until a negative intrathoracic pressure level in the range from about −1 cm H2O to about −15 cm H2O, the valve system assisting in increasing the magnitude and duration of negative intrathoracic pressure thereby enhancing the amount of blood flow in the heart and lungs and lowering intracranial pressure, therein further increasing blood flow to the brain.

In one embodiment, the invention provides a device for decreasing intracranial or intraocular pressures. The device comprises a housing having an inlet opening and an outlet opening that is adapted to be interfaced with a person's airway. The device further includes a valve system that is operable to regulate respiratory gas flows through the housing and into the person's lungs during spontaneous or artificial inspiration. The valve system assists in lowering intrathoracic pressures during each inspiration to repetitively lower pressures in the venous blood vessels that transport blood out of the head to thereby reduce intracranial or intraocular pressures.

In one embodiment, the invention provides a medical method for treating a person and comprises repeatedly compressing the person's chest. While repeatedly compressing the person's chest, the method further includes repeatedly delivering a positive pressure breath to the person and extracting respiratory gases from the person's airway using a vacuum following the positive pressure breath to create an intrathoracic vacuum to lower pressures in the thorax and to enhance blood flow back to the heart.

Systems and methods are provided for decreasing intracranial pressure and enhancing circulation in a breathing person, as well as for increasing the respiratory rate and encouraging spontaneous respiration. According to such methods, a valve system is interfaced to a person's airway. The valve system has a threshold valve and an airway member that interfaces with the person's airway. The threshold valve is configured to prevent respiratory gas flow to the person's lungs during a portion of an inhalation event until the inspiration equals or exceeds an opening pressure of the threshold valve. Also, a small level of external vacuum is constantly supplied at a juncture between the threshold valve and the airway member.

Systems and methods are provided for decreasing intracranial pressure and enhancing circulation in a breathing person, as well as for increasing the respiratory rate and encouraging spontaneous respiration. According to such methods, a valve system is interfaced to a person's airway. The valve system has a threshold valve and an airway member that interfaces with the person's airway. The threshold valve is configured to prevent respiratory gas flow to the person's lungs during a portion of an inhalation event until the inspiration equals or exceeds an opening pressure of the threshold valve. Also, a small level of external vacuum is constantly supplied at a juncture between the threshold valve and the airway member.

A method of positioning a patient or person 0 to 90 degrees in an upright position or greater in a supine or prone position while maintaining neutral skeletal alignment (non flexed position) with a body positioning mattress capable of applying a vacuum process to remove air; molding the mattress around the body to maintain position. A means to place the support mattress onto a manual or motorized bed frame to position and maintain a patient or person 0 to 90 degrees or greater in the supine or prone position.

A method for performing cardiopulmonary resuscitation (CPR) includes elevating the heart of an individual to a first height relative to a lower body of the individual. The lower body may be in a substantially horizontal plane. The method may also include elevating the head of the individual to a second height relative to the lower body of the individual. The second height may be greater than the first height. The method may further include performing one or more of a type of CPR or a type of intrathoracic pressure regulation while elevating the heart and the head. The first height and the second height may be determined based on one or both of the type of CPR or the type of intrathoracic pressure regulation.

The present invention provides compositions, methods for lyophilizing compounds and making pharmaceutical compositions, and kits providing solutions and lyophilized formulations of compounds. The compositions, methods, and kits are particularly useful in pharmaceutical applications involving therapeutic agents that have low solubility at low pH and medium pH values. Certain embodiments provide methods for lyophilizing compounds in liquid solutions, which include the steps of: a) preparing aqueous solutions of a compound of interest in the absence of buffer; b) adjusting the pH to high values of pH in order to increase the solubility of the compound of interest; and c) freeze-drying the solution to provide a lyophilized solid composition. Aqueous solutions including buffer are also disclosed. Lyophilized formulations, including micronized and non-micronized powders, are provided.

Increasing intranasal lymphatic circulation as a means of decreasing intracranial pressure in traumatic brain injury.

The present invention relates generally to a device and method for treating tissues of the central nervous system and more particularly, but not exclusively, to a device and method for treating the brain tissue.

A method for performing cardiopulmonary resuscitation (CPR) includes elevating the heart of an individual to a first height relative to a lower body of the individual. The lower body may be in a substantially horizontal plane. The method may also include elevating the head of the individual to a second height relative to the lower body of the individual. The second height may be greater than the first height. The method may further include performing one or more of a type of CPR or a type of intrathoracic pressure regulation while elevating the heart and the head. The first height and the second height may be determined based on one or both of the type of CPR or the type of intrathoracic pressure regulation.

An elevation device used in the performance of cardiopulmonary resuscitation (CPR) includes a base and an upper support pivotably coupled to the base. The upper support is configured to elevate the individual's upper back, shoulders and head when pivoted. The upper support is expandable lengthwise. The upper support includes a neck support that is configured to support the individual's spine in a region of the individual's C7 and C8 vertebrae throughout elevation of the upper back, shoulders and head.

The invention discloses a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases, which is prepared from the following bulk drugs: leech, lumbricus, scorpio and pseudo-ginseng. The traditional Chinese medicine composition disclosed by the invention accords with the theories of traditional Chinese medicine pharmacology of removing stasis, promoting new and self-quenching wind through blood circulation; in addition, by utilizing the traditional Chinese medicine composition formula, the traditional Chinese medicine composition disclosed by the invention is capable of promoting circulation, removing stasis, removing blood stasis, clearing hematoma, stopping rehaemorrhagia, reducing intracranial pressure, eliminating encephaledema, adjusting whole-body blood, resisting stress reaction and improving microcirculation and has the unique curative effects to perennial serious hypertension, cerebral hemorrhage, stroke, coronary heart disease and cerebral thrombosis.

A system includes a guidance device that provides feedback to a user to compress a patient's chest at a rate of between about 90 and 110 compressions per minute and at a depth of between about 4.5 centimeters to about 6 centimeters. The system includes a pressure regulation system having a pressure-responsive valve that is configured to be coupled to a patient's airway. The pressure-responsive valve is configured to remain closed during successive chest compressions in order to permit removal at least about 200 ml from the lungs in order to lower intracranial pressure to improve survival with favorable neurological function. The pressure-responsive valve is configured to remain closed until the negative pressure within the patient's airway reaches about −7 cm H2O, at which time the pressure-responsive valve is configured to open to provide respiratory gases to flow to the lungs through the pressure-responsive valve.

The invention discloses injection of mannite and glycerol, which contains mannite, glycerol and water for injection. Furthermore, the invention also discloses a method for preparing the injection, which comprises the following steps: taking the mannite and the glycerol, dissolving into the water for injection, filtering and filling. The injection of the mannite and the glycerol is clinically used for treating cerebrovascular diseases, brain trauma, cerebral tumors, intracranial inflammation and the diseases of acute and chronic intracranial hypertension, hydrocephalus and the like caused by other reasons. The injection of the mannite and the glycerol has the functions of lowering the intracranial pressure quickly and eliminating the hydrocephalus and can also avoid death because of acute renal failure caused by the injury of the kidney; the injection of the mannite and the glycerol suppresses the apoptosis of neural cells and achieves the function of protecting the brain; the function of lowering the intracranial pressure is stable and has long retention time; crystals occurring because of the change of the air temperature or in the processes of storage and transportation are eliminated; and the glycerol is used as a caloric agent and can improve and recover the energy metabolism of the important viscera of the heart, the brain, the kidney and the like during oxygen deficiency. The injection of the mannite and the glycerol is a very effective, stable and safe medicine for promoting urination and removing water clinically.

The invention relates to a Chinese materia medica preparation for treating hydrocephalus, which is prepared by the bulk drugs with weight as follows: 300-340g of cornus officinalis, 160-200g of deerhorn glue, 300-340g of twotooth achyranthes root, 390-410g of yam, 390-410g of Indian buead, 390-410g of grifola, 300-340g of oriental waterplantain rhizome, 300-340g of tree peony bark, 300-340g of motherwort fruit and 160-200g of radix astragali. The preparation method comprises the following steps: (1) weighing other drugs except the deerhorn glue according to the prescribed doses, adding 6-8 times of water to the drugs and decocting the drugs for three times, with 1.5-2h every time, combining and filtering decoction; (2) taking prescribed doses of the deerhorn glue and grinding the deerhorn glue into coarse powder, adding the powder into the decoction in the step (1) and melting the mixture by heat, filtering the mixture, concentrating filtrate into extract with relative density of 1.33-1.38, adding powdered sugar and dextrin to the extract based on the weight ratio of 1:2:1 among the extract, powdered sugar and dextrin, and adding proper amount of ethanol to prepare soft materials, pelletizing and drying the soft materials, and obtaining the Chinese materia medica preparation after pelletizing. The Chinese materia medica preparation has evident effect, no obvious toxic side effect, and simple preparation process, and is suitable for infantile hydrocephalus, communicating hydrocephalus, normal-pressure hydrocephalus and intracranial pressure reduction, etc.

The invention provides a sleep-aiding control method and device, and the method comprises the steps: a relaxing stage: controlling an electric bed to execute a human body relaxing mode so as to relax and massage the muscles of a human body; and in the sleep-aiding stage, controlling the electric bed to execute a body position sleep-aiding mode so as to promote intracranial venous return of the human body. According to the sleep-aiding control method and device provided by the invention, the human body is moderately stretched and vibratively massaged in a relaxing stage, tense muscles of the human body are relieved, muscle fatigue is eliminated, the comfort of the human body is improved, and the human body enters a deep relaxing state, and then enters a sleep-aiding stage, so that the head of the human body is raised, extravasated blood in the lung is reduced, and the oxygen inhalation amount is increased; in addition, intracranial pressure is relieved, intracranial venous return is promoted, blood can circulate in the brain as soon as possible, a human body is helped to enter the sleep stage quickly, fatigue can be eliminated, blood and oxygen can be promoted to enter the brain as soon as possible, and the human body can enter the sleep state more quickly through the two stages.

The invention discloses a Chinese medicinal composition for treating cerebral hemorrhage, which relates to the technical field of Chinese medicine. The composition consists of the following components in parts by weight: 8-16 parts of leech, 6-18 parts of giant knotweed, 8-16 parts of astragalus, 6-14 parts of safflower, 10-20 parts of pseudo-ginseng root, 10-20 parts of common selfheal fruit-spike, 10-20 parts of red paeony root, 6-16 parts of chaff flower root, 6-12 parts of ginkgo leaf and 6-18 parts of liquoric root. The Chinese medicinal composition for treating cerebral hemorrhage has the advantages of reasonable composition, short treatment course, high curing rate, no sequelae, safety, reliability and low price. The invention further provides a preparation method for the Chinese medicinal composition for treating cerebral hemorrhage; and the method has a simple process, and is suitable for industrial mass production.

A method for treating head injury in a mammal is provided. The method comprises administering to a mammal having a head injury an effective amount of a hemoglobin preparation. A preferred hemoglobin for use in the method is diaspirin crosslinked hemoglobin.

The current invention provides new methods and means for the prevention and treatment of ageing-related symptoms and diseases. The invention discloses mannitol 5 and / or proline containing compositions that are particularly useful for the treatment of premature ageing related symptoms in mammalian subjects suffering from genetic defects in DNA damage response and genome maintenance pathways. Humans suffering from Cockayne syndrome (CS), Xeroderma pigmentosum (XP), combined XPCS, trichothiodystrophy (TTD), COFS (cerebro-oculo-facio-skeletal syndrome), 10 XFE disorder (Xpf-Erccl syndrome), Bloom Syndrome (BS), Werner Syndrome (WS), Ataxia telangiectasia (AT), Fanconi Anemia (FA), Hutchinson Guilford Progeria (HGP) may be treated with pharmaceutical compositions comprising mannitol and / or proline according to this invention.

The invention belongs to the technical field of agriculture planting and discloses a planting method capable of reducing content of cyanophoric glycosides in cherry fruits. The method comprises steps as follows: (1) forest land control; (2) forest land clearing; (3) density control; (4) preparation of afforestation land; (5) application of base fertilizer and backfilling of surface soil: 10-20 kg of compost is applied to each hole while backfilling of the surface soil is performed, and 5-10 kg of a mannitol solution is sprayed to each hole; (6) selection of seedlings; (7) planting; (8) cultivation management. The planting method capable of reducing the content of cyanophoric glycosides in the cherry fruits is provided, the content of cyanophoric glycosides in the cherry fruits is reduced, and the economic benefits of planting are improved.

The present invention provides compositions, methods for lyophilizing compounds and making pharmaceutical compositions, and kits providing solutions and lyophilized formulations of compounds. The compositions, methods, and kits are particularly useful in pharmaceutical applications involving therapeutic agents that have low solubility at low pH and medium pH values. Certain embodiments provide methods for lyophilizing compounds in liquid solutions, which include the steps of: a) preparing aqueous solutions of a compound of interest in the absence of buffer; b) adjusting the pH to high values of pH in order to increase the solubility of the compound of interest; and c) freeze-drying the solution to provide a lyophilized solid composition. Aqueous solutions including buffer are also disclosed. Lyophilized formulations, including micronized and non-micronized powders, are provided.

The invention discloses a head and neck lymph drainage regulation and control instrument and a use method thereof, and relates to the field of clinical neurology (neurosurgery and neurology). The head and neck lymph drainage regulation and control instrument comprises a drainage pump and a drainage head sleeve. The drainage head sleeve comprises a head beam, a locking knob, pressing earmuffs, an inflation bandage and an air pipe. An air bag structure is used for replacing human hands for massage, and the drainage speed of a lymphatic system to brain metabolites is increased by pressing lymphatic tissues in front of ears, behind ears and at the lower jaw, so that the purposes of reducing intracranial pressure and discharging toxic macromolecular proteins generated by metabolism of the brain tissues out of the cranium are achieved. When the physical method is used for massaging the head lymph of a patient, the discharge of intracranial harmful substances can be accelerated, the intracranial pressure of the patient can be reduced, the opportunity that the patient is subjected to surgical treatment can be reduced or avoided, the accumulation of intracranial harmful metabolites of the craniotomy patient can be reduced, the postoperative infection risk can be reduced or avoided, the discharge of head metabolic toxic macromolecular proteins can be accelerated, and the memory, sleep and neurocognition can be improved.

The invention discloses a traditional Chinese medicine for treating cerebral hemorrhage diseases. The traditional Chinese medicine consists of the following raw materials in parts by weight: 30-35 parts of scorpio, 15-25 parts of uncaria, 30-35 parts of earthworm, 25-30 parts of typhonium giganteum, 5-10 parts of cassia twig, 25-30 parts of salvia miltiorrhiza, 2-4 parts of bud apocynum venetum, 30-35 parts of gastrodia elata, 5-6 parts of fructus cannabis, 30-35 parts of rhizoma acori graminei and 5-8 parts of additive, wherein the additive is a mixture of xylitol and citric acid. The traditional Chinese medicine is convenient to take, short in course of treatment and fast in effectiveness and does not have a toxic or side effect, and drug dependence is avoided.

The invention discloses a head lymph massage instrument and a using method thereof, and relates to the field of neurosurgery, the head lymph massage instrument comprises a drainage pump and an inflation drainage head sleeve, and the drainage pump comprises an inflation module, a control module, a display module, a shell and a switch. According to the head lymph massage instrument and the using method thereof, a physical therapy is used for replacing manual massage, pressing type drainage is conducted on lymphatic systems in front of the ears, behind the ears and at the lower jaw of a patient, and drainage in front of the ears and behind the ears is drained to the clavicle from top to bottom in the jugular vein direction; the chin drainage starts from the chin and drains towards the inflection point of the mandibular angle from front to back along the mandible, so that a doctor can be helped to massage the head lymph of a patient by using a physical technique under the condition of not performing craniotomy or skull drilling and intubation, the intracranial pressure of the patient is reduced, the surgical pain of the patient is relieved, the intracardiac pressure is reduced, and the postoperative infection risk is avoided.