12 results about "Mannitol solution" patented technology

The invention relates to the technical field of sewage treatment, and discloses a photocatalytic material and a preparation method and application thereof.The method comprises the following steps that bismuth nitrate pentahydrate and sodium bromide are added into a mannitol solution according to the molar ratio of 1: 1.5, and ultrasonic dispersion is conducted to form turbid liquid; adding arginine into the turbid liquid, wherein the molar ratio of the arginine to the bismuth nitrate pentahydrate is (0-2.5): 1; adjusting the pH value of the turbid liquid and stirring to obtain a precipitate; the precipitate is filtered, washed and dried, and the photocatalytic material nVBi-(110) BiOBr is obtained.By means of the photocatalytic material, the removal rate of hexavalent chromium in alkaline wastewater with the pH being 7-10 can still exceed 90% within a short time, the photocatalytic material shows excellent stability and reaction activity, the technical problem that hexavalent chromium is difficult to remove efficiently in the alkaline environment is successfully solved, and the photocatalytic material has good application prospects. The method has important environmental application value and popularization potential.

The invention relates to a preparation method and application of an ultra-efficient nitrate-based free radical activation catalyst, and the preparation method comprises the following steps: S1, dissolving bismuth nitrate Bi (NO3) 3.5 H2O and polyvinylpyrrolidone (PVP) in a mannitol solution; s2, adding potassium bromide into the solution in the step S1, and performing ultrasonic treatment to form a white suspension; s3, transferring the suspension into a high-pressure reaction kettle for hydrothermal reaction; and S4, after the reaction is completed, cooling, centrifugally collecting precipitates, washing, and carrying out vacuum freeze drying to obtain the bismuth oxybromide BixOBr nanosheet catalyst. According to the application of the super-efficient nitrate-based free radical activation catalyst in degradation of organic pollutants, the bismuth oxybromide BixOBr nanosheet catalyst is added into a water body containing nitrate, the nitrate is activated to generate free radicals by utilizing the piezoelectric effect induced by photoinduced deformation of the photocatalyst under the condition that an external electric field and an oxidizing agent are not needed, and the degradation efficiency of the nitrate-based free radical activation catalyst is improved. Therefore, organic pollutants are degraded.

The application belongs to the technical field of medicines, and relates to a ferric bismuth oxide multi-modal imaging probe and a preparation method and application thereof. x The ferric bismuth oxide multi-modal imaging probe has a molecular formula of BiFeO x wherein x is 2.5-3.5, the ferric bismuth oxide multi-modal imaging probe has CT imaging and MRI imaging functions, and has POD-like activity, CAT-like activity and GSH-Px-like activity. The preparation method comprises the following steps: dissolving bismuth nitrate in a mannitol solution, then adding a high-molecular polymer to form an A solution; dissolving ferric nitrate in a mannitol solution to form a B solution; dropping the B solution into the A solution, then adding ammonia water, performing high-temperature treatment after reaction, and obtaining the ferric bismuth oxide multi-modal imaging probe after cooling and washing. The ferric bismuth oxide multi-modal imaging probe has significant advantages in multi-modal imaging and tumor treatment, overcomes part of the limitations of single imaging technology and traditional treatment methods, and has important clinical application value.

The invention discloses an exocytosis protein subcellular localization method for mannitol-induced plasm-wall separation, and relates to the technical field of cytobiology, the method comprises the following specific steps: constructing a fusion expression vector: connecting a plant target exocytosis protein gene with a fluorescent protein gene through a gene cloning technology to obtain a fusion expression vector; inserting into a plant expression vector to obtain a recombinant expression vector containing the target extracellular secretory protein-fluorescent protein fusion gene; performing bacterial colony PCR identification and sequencing verification on the recombinant expression vector; by adopting an agrobacterium tumefaciens-mediated plant leaf instantaneous transformation technology, the fusion gene is rapidly expressed in plant cells, subsequent experiments can be carried out after culture is carried out for 2-3 days, the experiment period is greatly shortened, meanwhile, leaf cells are induced to be subjected to plasmon-wall separation through a gradient mannitol solution, positive cell screening and identification are not needed, and the application prospect is wide. And positioning can be realized by directly observing fluorescence signal distribution by using a laser confocal microscope.

The invention discloses low-cholesterol liquid lard oil and a preparation method thereof, and relates to the technical field of grease processing. Unprocessed lard oil is used as a raw material, water is used as a medium, and selective separation of the liquid lard oil is realized through aqueous method fractionation and addition of a proper amount of a mannitol aqueous solution before cooling crystallization; and the prepared liquid lard oil is low in cholesterol content, so that the eating quality of the liquid lard oil is improved, and the market competitiveness of the liquid lard oil is improved.

This invention relates to the field of pharmaceutical preparations, specifically to a method for preparing a lyophilized bortezomib for injection. The method for preparing a lyophilized bortezomib for injection provided by this invention includes preparing bortezomib mannitol ester and preparing a lyophilized bortezomib for injection. The preparation of bortezomib mannitol ester includes the following steps: adding mannitol to purified water and stirring to dissolve it to form a mannitol solution; adding tert-butanol to the mannitol solution and stirring until homogeneous to form a mixture; adding bortezomib to the resulting mixture and stirring until completely dissolved to form a bortezomib mannitol ester solution; filtering the resulting bortezomib mannitol ester solution, dispensing the filtrate into stainless steel trays, and placing them in a lyophilization chamber; lyophilizing, collecting the lyophilized powder, and obtaining bortezomib mannitol ester. This invention effectively overcomes the problems of foreign matter in lyophilized bortezomib preparations and poor clarity after reconstitution.

The application belongs to the field of photocatalytic environmental remediation, and particularly relates to a preparation method and application of a Bi-BiO / BiOCl ternary Z-type heterojunction. The preparation method comprises the following steps: S1, adding Bi(NO3)3.5H2O and PVP into a mannitol solution, then adding a sodium chloride solution dropwise, and then performing a hydrothermal reaction, and obtaining BiOCl nanosheets after cooling, centrifuging and washing the product; S2, mixing HNO3 solution, ethylene glycol and water to form a mixed solution, adding Bi(NO3)3.5H2O into the mixed solution and stirring until a transparent solution is formed, then adding the BiOCl nanosheets into the transparent solution to form a suspension; S3, performing a hydrothermal reaction on the suspension obtained in step S2, and obtaining the Bi-BiO / BiOCl ternary Z-type heterojunction after cooling, centrifuging, washing and drying the product. The Bi-BiO is loaded on the surface of the BiOCl through a two-step hydrothermal method to construct a Z-type heterojunction photocatalyst, which improves the photoelectron-hole separation capacity and light absorption range of the material, and further increases the oxygen vacancy concentration of the material, so that the Z-type heterojunction photocatalyst has excellent photocatalytic activity.

The application discloses a humidity control and long block bud grafting method for improving the survival rate of ginkgo grafting and special biological active dressing. The method comprises the following steps: pretreating the scion with 50-100 mg / L mannitol solution for 30-60 minutes; cutting a long block bud piece with a thin layer of xylem, the long block bud piece being 3.0-4.0 cm long and 1.5-2.5 cm wide, and ensuring that the cambium is precisely connected; smearing the grafting interface with special dressing containing 0.01%-0.05% indole butyric acid and 0.5%-1.0% carbendazim; and wrapping the grafting interface with a degradable grafting film, and keeping the temperature at 20-28 DEG C and the humidity at greater than or equal to 80% until callus formation. The dressing is composed of 0.01%-0.05% indole butyric acid, 0.5%-1.0% carbendazim and the rest of the base material in percentage by mass. The application solves the problems of water loss, slow healing and susceptibility to infection in ginkgo grafting by combining endogenous water retention, exogenous healing promotion and standard operation, and the survival rate is stably improved to more than 95%, and the optimal survival rate is 98%. The method is simple to operate and suitable for large-scale promotion.

The invention provides a preserving fluid for stably preserving umbilical cord mesenchymal stem cell exosomes for a long time, which belongs to the technical field of biotechnology and comprises the following components: a mannitol solution, a dimethyl sulfoxide solution, a human serum albumin solution and beta-nicotinamide mononucleotide. The invention provides a preserving fluid for stably preserving umbilical cord mesenchymal stem cell exosomes for a long time. The number and physicochemical properties of the umbilical cord mesenchymal stem cell exosomes are protected from being affected by freezing.

The utility model relates to the technical field of medical equipment, in particular to a heating device for mannitol, which comprises a placing frame, two fixing blocks fixedly connected to the periphery of the placing frame, hanging rods rotatably connected to the interiors of the fixing blocks, a water storage bin fixedly connected to the interior of the placing frame, and a plurality of heating wires fixedly connected to the interior of the water storage bin. A cover plate is fixedly connected to the top of the placing frame, a temperature detector is arranged on the periphery of the placing frame, a plurality of connecting rods are fixedly connected to the top of the cover plate, and a shaking mechanism is arranged on the top of a hanging rod, so that a mannitol solution is uniformly heated, and solution deterioration caused by too high temperature of part of the mannitol solution is prevented; the body health of the patient is influenced.

The invention relates to a method for improving the yield of mannitol through alcohol precipitation, which comprises the following steps: concentrating to obtain a mannitol concentrated solution, cooling to a process temperature, adding methanol in a fed-batch manner, continuously cooling after adding methanol, then separating a crystallization solution, and improving the yield of mannitol through alcohol precipitation. According to the present invention, the solubility of mannitol in methanol is low, and the methanol is added to the mannitol solution to crystallize, such that the yield of the obtained mannitol is 15% or more higher than the yield of the mannitol crystallization in the aqueous solution; the method is simple and easy to implement, low in production cost and high in feasibility.

A preparation method and application of an ultra-efficient nitrate-based free radical activation catalyst, the preparation method comprising the following steps: S1: dissolving bismuth nitrate Bi(NO3)3·5H2O and polyvinylpyrrolidone (PVP) in a mannitol solution; S2: adding potassium bromide to the solution in step S1, and ultrasonically treating the solution to form a white suspension; S3: transferring the suspension to a high-pressure reactor for hydrothermal reaction; S4: cooling after the reaction is completed, collecting the precipitate by centrifugation, washing, and vacuum freeze-drying to obtain bismuth oxybromide Bi(NO3)3·5H2O. x OBr nanosheet catalyst. The application of the ultra-efficient nitrate-based free radical activation catalyst in the degradation of organic pollutants is to x OBr nanosheet catalysts are added to nitrate-containing water, and their photoinduced deformation-induced piezoelectric effect is used to activate nitrate to produce free radicals without the need for an external electric field or oxidant, thereby degrading organic pollutants.