3 results about "Premature ageing" patented technology

This invention provides a method, system, and storage medium for assessing the vascular physiological age of hypertensive patients, belonging to the field of intelligent medical technology. The method includes: acquiring assessment data to characterize the vascular state of hypertensive patients, and constructing a sequence of vascular feature parameters based on the assessment data; inputting the vascular feature parameter sequence into a pre-trained vascular physiological age prediction model to perform feature learning processing, and outputting vascular physiological age parameters; inputting the vascular physiological age parameters into a time-series analysis model to perform trend analysis processing, generating longitudinal aging feature parameters; judging the degree of premature aging of blood vessels based on the longitudinal aging feature parameters, and outputting the vascular physiological age assessment result of the hypertensive patient. This invention achieves reliable processing of the vascular physiological age and stable assessment of the degree of premature aging for individual hypertensive patients.

The application discloses a polypeptide UPCP and application thereof in preparation of anti-aging products. The polypeptide UPCP provided by the application has an amino acid sequence of sequence 4 in the sequence list. The polypeptide is applied in preparation of products with any one of the following functions: 1) treating children's premature aging; 2) delaying physiological aging of mammals or cells thereof; 3) improving premature aging of mammals; the improvement of premature aging of mammals is embodied in delaying premature aging of mammals; 4) improving body weight of premature aging animals; the improvement of body weight of premature aging animals is embodied in increasing body weight of premature aging animals; 5) relieving motor dysfunction of premature aging animals; 6) prolonging survival period of premature aging animals, etc. The application develops a specific peptide (UPCP) which can inhibit HGPS cell aging, improve aging characteristics of HGPS premature aging mice and prolong survival period, and provides a new strategy for treatment of HGPS.