31 results about "Lymph drainage" patented technology

In accordance with the present invention, there are provided methods for identifying the sentinel lymph node in a drainage field for a tissue or organ in a subject. In select embodiments, the invention allows for the identification of the first or sentinel lymph node that drains the tissue or organ, particularly those tissues associated with neoplastic or infectious diseases and disorders, and within the pertinent lymph drainage basin. Once the drainage basin from the tissue or organ, i.e., the sentinel lymph node, is identified, a pre-operative or intraoperative mapping of the affected lymphatic structure can be carried out with a contrast agent. Identification of the first or sentinel lymph node, on the most direct drainage pathway in the drainage field, can be accomplished by a variety of imaging techniques, including ultrasound, MRI, CT, nuclear and others. Moreover, once the lymphatic structure is identified as being associated with neoplastic or infectious diseases and disorders, the affected lymphatic structure can be removed surgically or by a suitable minimally invasive procedure to allow pathological analysis to be performed to determine whether certain diseases or disorders exist, without resort to more radical lymphadenectomy. Further, the agent can be made to carry diagnostic or therapeutic probes to be activated and / or delivered to the injection site or any part of the lymphatic pathway downstream from the injection site.

Methods and devices are disclosed for selective delivery of therapeutic substances to specific histologic or microanatomic areas of organs. Introduction of the therapeutic substance into a hollow organ space (such as an hepatobiliary duct or the gallbladder lumen) at a controlled pressure, volume or rate allows the substance to reach a predetermined cellular layer (such as the ephithelium or sub-epithelial space). The volume or flow rate of the substance can be controlled so that the intralumenal pressure reaches a predetermined threshold level beyond which subsequent subepithelial delivery of the substance occurs. Alternatively, a lower pressure is selected that does not exceed the threshold level, so that delivery occurs substantially only to the epithelial layer. Such site specific delivery of therapeutic agents permits localized delivery of substances (for example to the interstitial tissue of an organ) in concentrations that may otherwise produce systemic toxicity. Occlusion of venous or lymphatic drainage from the organ can also help prevent systemic administration of therapeutic substances, and increase selective delivery to superficial epithelial cellular layers. Delivery of genetic vectors can also be better targeted to cells where gene expression is desired. The access device comprises a cannula with a wall piercing tracar within the lumen. Two axially spaced inflatable balloons engage the wall securing the cannula and sealing the puncture site. A catheter equipped with an occlusion balloon is guided through the cannula to the location where the therapeutic substance is to be delivered.

The present invention relates to a circular knit fabric for use in compression therapy of lymphedemas, having a surface with a patterned structure with protuberances (1) which, when in contact with the body part to be treated with compression therapy, exert pressure on the surface of the body part and which, when the body part moves, produce a massaging effect. To create such a circular knit fabric that is comfortable to the wearer and that, when worn, exerts a sufficiently high compressive pressure on the body part to be treated and, at the same time, improves lymph drainage, the invention proposes that the structured surface have a regular pattern in the form of chambers (2) that are bounded by protuberances (1), with the chambers (2a, 2b, 2c) that are adjacent to each other being connected to each other by means of connecting channels (3) in the longitudinal direction (L) of the circular knit fabric.

The invention discloses a pelvic tumor CTV automatic sketching method based on deep learning, which is suitable for a pelvic lymphatic drainage area, cervical cancer CTV and rectal cancer CTV. The automatic sketching method comprises the following steps: S1, collecting CT image data and marking drainage area subareas by a clinician, and preprocessing the image data; S2, constructing a drainage area subarea deep learning segmentation model; S3, obtaining CT image data and drainage area subarea images marked by clinicians through processing in the step S1 and the step S2, inputting the data and the images into a network, training the network, and obtaining subarea contours ; S4, automatically generating a cervical cancer CTV contour through the subarea contours; and S5, automatically generating a rectal cancer CTV contour through the subarea contours. The automatic sketching method can assist doctors in sketching cervical cancer CTV and rectal cancer CTV according to patient conditions and staging conditions of patients, and an introduced dense network can effectively improve the recognition capability of pelvic lymphatic drainage areas.

The invention discloses a method for automatically delineating the drainage area and metastatic lymph nodes of head and neck nasopharyngeal carcinoma, belonging to the field of medical image processing, which includes the following steps: S1: collecting and processing case data, wherein the case data includes DICOM image; S2: Establish and train the partition model of the lymphatic drainage area; S3: According to the segmentation network of the lymphatic drainage area obtained in step S2, predict each partition of the drainage area of ​​all DICOM data, and obtain the left and right sub-regions of each partition after post-processing Segmentation; S4: Establish and train the automatic lymph node segmentation network model; S5: Input the case data into the lymphatic drainage area segmentation model and the automatic lymph node segmentation network model in turn, and obtain the drainage area and lymph node segmentation results. The invention can reduce the burden of the doctor's target region delineation during radiotherapy, improve the efficiency of the doctor's delineation, and reduce the subjectivity of the doctor's delineation.

The invention discloses a method for removing baggy eyelids and nasolabial folds, and relates to the technical field of skin care. The method comprises the following steps: Step 1: firstly, primarily cleaning facial skin and eye skin by using a facial cleanser to remove dust and greasy dirt on the surface, and then selecting a soft towel to absorb moisture on the faces; Step 2, deeply cleaning the facial skin by using a microwave whitening instrument, and more thoroughly removing bacteria, dirt and redundant cutin by using a microwave heat effect; and Step 3, after detoxification essential oil is smeared on the face skin and the eye skin, using a lymphatic drainage instrument for performing lymphatic acupoint detoxification on the lymphatic systems of the faces and the eyes, and massaging the faces and the eyes after detoxification is completed. According to the method for removing baggy eyelids and nasolabial folds, the lymphatic system of the faces and the eyes is deeply massaged and detoxified through a lymphatic drainage instrument, blood circulation is promoted, the skin of the faces and the eyes is conditioned from inside to outside, the cell viability is improved, and beneficial substances in essence are conveniently absorbed.

The invention belongs to the technical field of nanoprobes, and specifically relates to a method for tracing deep cervical lymph nodes and meningeal lymphatic vessels using nanotechnology. The method is constructed with polyglycolide lactide and pluronic F127 as main raw materials The resulting core-shell nanoparticles are used as a model nano drug-loading system (particle size 20-50 nm), and the near-infrared fluorescent dye Cy5 is loaded to form a nanoprobe. After the nanoprobe was injected subcutaneously in the right neck, the nanoprobe was enriched to the superficial cervical lymph nodes, deep cervical lymph nodes and axillary lymph nodes through the local lymphatic drainage of the tissue, and the deep cervical lymph nodes and meningeal lymphatic vessels directly connected. Therefore, nanoprobes can be rapidly transported to the meningeal lymphatic vessels for real-time imaging and tracing of deep cervical lymph nodes and meningeal lymphatic vessels, providing a basis for research on the lymphatic transport of nanoparticles in the neck and the physiology and pathology of the brain lymphatic system. Simple and direct means of detection.

An automated system and method, wherein a movement device aids in lymphatic drainage and activation of the lymphatic system by applying a skin safe medium on the skin or on or near the lymph gland(s) creating an automated repetitive drainage effect that may allow patients to be more successful at reducing and managing their swelling.

The invention relates to the field of lymphatic drainage instruments, in particular to a lymphedema limb tail end pressure treatment device which comprises a limb wearing belt worn on the arm and / or the leg of a patient and provided with an outer circumferential face and an inner circumferential face extending in the circumferential direction. a connecting mechanism is arranged on the limb wearing belt; a main control mechanism is detachably connected to the limb wearing belt and can slide on the limb wearing belt; At least one limb front end wearing belt is worn on fingers and / or toes of a patient and are provided with inner peripheral surfaces of outer peripheral surfaces extending in the circumferential direction, and each limb front end wearing belt is communicated with the main control mechanism through a connecting pipeline; according to the invention, the defect that the traditional interstitial airwave pressure therapy (IPC) cannot be used for lymphatic drainage of fingers and toes can be overcome, and a patient can be helped to better carry out detumescence treatment.

The invention discloses an automatic delineation system for pelvic tumor CTV based on deep learning, which is suitable for pelvic lymphatic drainage area, cervical cancer CTV and rectal cancer CTV. The automatic delineation system includes the following steps: Step S1: Collect CT image data and clinical The doctor marks the drainage area and preprocesses the image data; step S2: constructs the deep learning segmentation model of the drainage area; step S3: after the processing of steps S1 and S2, the CT image data and the image of the drainage area marked by the clinician are input into the network, Train the network to obtain the partition contour; step S4: automatically generate the cervical cancer CTV contour through the partition contour; and step S5: automatically generate the rectal cancer CTV contour through the partition contour. The automatic delineation system of the present invention can assist doctors in delineating cervical cancer CTV and rectal cancer CTV according to the patient's condition and staging situation, and the introduced dense network can effectively improve the identification ability of pelvic lymphatic drainage area.

The present invention relates to a mixture of active ingredients consisting of Taraxacum officinalis, Fagopyrum esculentum, Ruscus aculeatus, Solidago virgaurea and Orthosiphon stamineus or extracts of said plants or from said plants and extracts thereof, a composition comprising such a mixture, and uses thereof.

The embodiment of the present invention provides an automatic delineation method of head and neck lymph nodes and drainage areas based on deep learning. This method uses the symmetry of the human body structure to divide the head area into left and right parts for training and prediction, thereby indirectly increasing the number of models. The amount of training data, while reducing the size of the deep learning model. The present invention uses a delineation strategy of step-by-step processing and optimization. Firstly, the deep learning model is used to realize the easily segmented lymphatic drainage area, and then the multi-task deep learning model is used to optimize the lymphatic drainage area and segment the lymph nodes, making full use of the relationship between the two and improve the segmentation accuracy of the two. The present invention implements an artificial intelligence (AI)-assisted contouring method in the radiotherapy planning workflow, which can effectively improve the consistency of the contouring of the work efficiency of medical workers, and improve the accuracy of radiotherapy for head and neck tumors.

The invention discloses an automatic delineation method of the mediastinal lymphatic drainage area based on a deep learning network, which is suitable for CT images. The automatic delineation method includes the following steps: S1: collecting CT image data and images of the mediastinal lymphatic drainage area manually marked by doctors, And preprocess the CT image data and the images of the mediastinal lymphatic drainage area manually marked by doctors; S2: group the preprocessed CT image data to obtain the training set, verification set and test set; S3: pair the training set, verification set and test set Step S4: Build a deep learning segmentation model; and S5: Input the CT image data in the training set and the images of the mediastinal lymphatic drainage area manually marked by doctors into the deep learning segmentation model that has been constructed. After the training iterations converge, save The segmentation model of the mediastinal lymphatic drainage area, and then identify and predict the mediastinal lymphatic drainage area, and obtain the probability map of each partition of the mediastinal lymphatic drainage area. The network can better locate and segment small drainage areas.

An apparatus for draining lymph into vein includes a drainage device. The drainage device includes a chamber, an osmosis membrane, a first catheter, a second sensing element, and a pump. The chamber includes a chamber wall, wherein a chamber space is formed by the chamber wall, and a first opening is formed on the chamber wall. The osmosis membrane disposed on the first opening. One end of the first catheter connects to the chamber space, and the other end of the first catheter connects with a vein. The second sensing element receives a radio wave emitted by a first sensing element of a power supply device to send an electrical signal. The pump is disposed in the chamber and connecting to the second sensing element, wherein a negative pressure in the chamber space is generated by the pump to drain lymph into the vein via the first catheter.