Chinese medicinal composition for treating cerebral hemorrhage and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for the treatment of cerebral hemorrhage and its preparation, can solve the problems of difficult preparation and quality control of traditional Chinese medicine injections, complex components of traditional Chinese medicine injections, unclear active ingredients, etc., and achieve the reduction of intracerebral hematoma , non-toxic and side effects, the effect of reducing intracranial pressure

Active Publication Date: 2012-07-18
启东市三江建筑机械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Chinese patent CN100384464C discloses a medicine for treating cerebral hemorrhage, which consists of 8-12 parts of Direngen, 10-20 parts of Jiujiecha, 10-15 parts of Sanjiapi, 6-20 parts of Daji, and 15-25 parts of Salvia , 10-20 parts of holly, 20-30 parts of mulberry branch, 10-15 parts of motherwort, 12-20 parts of Ligustrum lucidum, 10-20 parts of Achyranthes bidentata, 10-15 parts of calamus calamus, etc., the clinical curative effect is good, but It is inconvenient to take this medicine, and it takes 280g of Chinese medicinal materials to decoct every day, three times a day, and take 150ml each time
However, the composition of traditional Chinese medicine injections is complex, and the active ingredients are not yet clear, which brings certain difficulties to the preparation and quality control of traditional Chinese medicine injections. In recent years, there have been more and more safety problems of traditional Chinese medicine injections.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Example 1: Weigh 10g of leeches, 9g of Polygonum cuspidatum, 12g of Radix Astragali, 10g of Safflower, 14g of Sanqi, 10g of Prunella vulgaris, 12g of Radix Paeoniae Rubra, 10g of Achyranthes bidentata, 6g of Ginkgo biloba leaves, and 12g of licorice.

[0057] 1) Take leech, safflower, Panax notoginseng, and Prunella vulgaris and crush them into coarse powder, soak them in 50% ethanol for 2 hours, then use 10 times the amount of coarse powder and 50% ethanol as solvent to reflux extract twice, each time for 2 hours, and combine the ethanol extracts Concentrate under reduced pressure to 0.5g / ml (including crude drug amount).

[0058] 2) Take Polygonum cuspidatum, Radix Astragali, Radix Paeoniae Rubra, Achyranthes bidentata, Ginkgo biloba, and licorice, and grind them into coarse powder, add 10 times the amount of water to decoct for 2 hours, filter, collect the filtrate and concentrate it under reduced pressure to 0.5g / ml (containing crude drug content).

[0059] 3) Combi...

Embodiment 2

[0060] Example 2: Weigh 8g of leech, 6g of Polygonum cuspidatum, 8g of Radix Astragali, 6g of Safflower, 10g of Panax notoginseng, 10g of Prunella vulgaris, 10g of Radix Paeoniae Rubra, 6g of Achyranthes bidentata, 6g of Ginkgo biloba, and 6g of licorice.

[0061] 1) Take leech, safflower, Panax notoginseng, and Prunella vulgaris and crush them into coarse powder, soak them in 50% ethanol for 2 hours, then use 10 times the amount of coarse powder and 50% ethanol as solvent to reflux extract twice, each time for 2 hours, and combine the ethanol extracts Concentrate under reduced pressure to 0.5g / ml (including crude drug amount).

[0062] 2) Take Polygonum cuspidatum, Radix Astragali, Radix Paeoniae Rubra, Achyranthes bidentata, Ginkgo biloba, and licorice, and grind them into coarse powder, add 10 times the amount of water to decoct for 2 hours, filter, collect the filtrate and concentrate it under reduced pressure to 0.5g / ml (containing crude drug content).

[0063] 3) Combine...

Embodiment 3

[0064] Example 3: Weigh 16g of leeches, 18g of Polygonum cuspidatum, 16g of Radix Astragali, 14g of Safflower, 20g of Panax notoginseng, 20g of Prunella vulgaris, 20g of Radix Paeoniae Rubra, 16g of Achyranthes bidentata, 12g of Ginkgo biloba leaves, and 18g of licorice.

[0065] 1) Take leech, safflower, Panax notoginseng, and Prunella vulgaris and crush them into coarse powder, soak them in 50% ethanol for 2 hours, then use 10 times the amount of coarse powder and 50% ethanol as solvent to reflux extract twice, each time for 2 hours, and combine the ethanol extracts Concentrate under reduced pressure to 0.5g / ml (including crude drug amount).

[0066] 2) Take Polygonum cuspidatum, Radix Astragali, Radix Paeoniae Rubra, Achyranthes bidentata, Ginkgo biloba, and licorice, and grind them into coarse powder, add 10 times the amount of water to decoct for 2 hours, filter, collect the filtrate and concentrate it under reduced pressure to 0.5g / ml (containing crude drug content).

[...

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PUM

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Abstract

The invention discloses a Chinese medicinal composition for treating cerebral hemorrhage, which relates to the technical field of Chinese medicine. The composition consists of the following components in parts by weight: 8-16 parts of leech, 6-18 parts of giant knotweed, 8-16 parts of astragalus, 6-14 parts of safflower, 10-20 parts of pseudo-ginseng root, 10-20 parts of common selfheal fruit-spike, 10-20 parts of red paeony root, 6-16 parts of chaff flower root, 6-12 parts of ginkgo leaf and 6-18 parts of liquoric root. The Chinese medicinal composition for treating cerebral hemorrhage has the advantages of reasonable composition, short treatment course, high curing rate, no sequelae, safety, reliability and low price. The invention further provides a preparation method for the Chinese medicinal composition for treating cerebral hemorrhage; and the method has a simple process, and is suitable for industrial mass production.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating cerebral hemorrhage and a preparation method thereof. Background technique [0002] Cerebral hemorrhage is a kind of cerebral apoplexy, which has the characteristics of rapid onset, rapid change, high disability rate and fatality rate, which seriously affects the quality of life of patients. There are many causes of cerebral hemorrhage, which can be divided into two categories: traumatic and non-traumatic. About 90% of non-injurious cerebral hemorrhage have a history of hypertension. Once hemorrhage, local blood circulation disorder in the brain will be caused, leading to symptoms of acute brain injury, such as hemiplegia, aphasia, and coma. Cerebral hemorrhage caused by craniocerebral trauma In normal times, craniocerebral trauma caused by industrial injuries and traffic accidents is very common. In wa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P9/10A61P7/04A61K35/62
Inventor 刘焕太
Owner 启东市三江建筑机械有限公司
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