208results about How to "Avoid dissociation" patented technology

An ion implantation device for vaporizing decaborane and other heat-sensitive materials via a novel vaporizer and vapor delivery system and delivering a controlled, low-pressure drop flow of vapors, e.g. decaborane, into the ion source. The ion implantation device includes an ion source which can operate without an arc plasma, which can improve the emittance properties and the purity of the beam and without a strong applied magnetic field, which can improve the emittance properties of the beam. The ion source is configured so that it can be retrofit into the ion source design space of an existing Bernas source-based ion implanters and the like or otherwise enabling compatibility with other ion source designs.

A downloadable agent facilitates medical image transmission in accordance with a clinical trial protocol. The agent includes program code for obtaining or receiving a medical image from a computer storage device or a DICOM-compliant diagnostic instrument, program code for accepting textual information about the patient or medical image and associating the textual information with the medical image to prevent dissociation of the textual information and the medical image, program code for executing a data compliance protocol, program code for encrypting the image and textual information and for compressing at least the image, and program code for transmitting the encrypted image and textual information across a wide area network to a remote translator for decompressing, de-encrypting and viewing of the image and textual information. The data compliance process prohibits inclusion of patient identity information in the associated textual information and medical image.

The invention relates inter alia to a bivalent, bispecific construct comprising an anti-IL-6 antibody, or derivative thereof, and an anti-IL-23 antibody, or derivative thereof and its use in therapy. The invention also relates to useful anti-IL-6 antibodies and anti-IL-23 antibodies.

On a substrate 1 is formed a first transparent electrode layer 3, on which a p-type semiconductor film 5, an i-type semiconductor film 6 and an n-type semiconductor film 7 are successively formed to constitute an electric power generating layer. On the n-type semiconductor film 7 is formed a second transparent electrode layer 8, on which a back electrode layer 9 is formed. Moreover, an intermediate layer 4 made of a given material is formed between the first transparent electrode layer 3 and the p-type semiconductor film 5 to complete a photovoltaic element 40 with high electric power generating efficiency (conversion efficiency).

This is a method and apparatus for accurately determining a NOx concentration of a measurement gas that contains H2O and/or CO2, without being affected by a dissociation of H2O and/or CO2.In this method and apparatus,(1) the NOx-measurement gas containing H2O and/or CO2 is introduced to travel through a heated flow channel formed by an oxygen ion conductive solid ceramic electrolyte body that electrically control amount of O2 from the flow channel,(2) while said measurement gas travels, a residual gas including NO and H2O and/or CO2 is formed from the measurement gas,(3) said residual gas is flowed to contact a catalytic electrode to which a negative polarity of a low voltage that does not dissociate H2O and/or CO2 but dissociates NO is applied, so that said electrode dissociates a NO gas of the residual gas into N ions and O ions and flows an electric current through the electrolyte body in proportion to an amount of the O ions dissociated from said residual gas at the electrode, and(4) the NOx concentration in the measurement gas is determined based on the current.The low voltage preferably applied in the above (3) is about 350-450 mV.

Provided are a metal halide perovskite light emitting device and a method of manufacturing the same. The metal halide perovskite light emitting device includes a substrate, a first electrode formed on the substrate, a light emitting layer formed on the first electrode and including a metal halide perovskite material, and a second electrode disposed on the light emitting layer, the first electrode includes a conductive layer and a surface energy-tuning layer disposed on the conductive layer, the conductive layer includes a conductive polymer and a first fluorine-based material, and the surface energy-tuning layer includes a second fluorine-based material but does not include the conductive polymer. Therefore, the first electrode can come in ohmic contact with a metal halide perovskite light emitting layer by adjusting a work function, and can prevent the dissociation of excitons to enhance luminous efficiency, thereby effectively improving efficiency of a light emitting device.

The invention relates to a vehicle-mounted air purifier. Air inlets are formed on the front side and the rear side of a shell, and an air outlet is formed on the bottom surface; an air duct, a fan, an air purification module and a power supply system are arranged in the shell; the fan is arranged at the central position of the air duct; cold catalyst plates, stainless steel plates and photocatalyst plates of the air purification module are symmetrically arranged from the air inlets on the front side and the rear side of the shell to the inside of the shell sequentially by taking the fan as a symmetric center parallel to an arc-shaped plate and are fixed on the four walls of the air duct through supporting frames respectively; plasma generating electrodes are parallelly arranged on the air duct walls between the stainless steel plates and the photocatalyst plates; ultraviolet lamps are symmetrically arranged on both sides of the fan; the air outlet of the shell is provided with a high efficiency particulate air (HEPA) filtering material; a transformer and a ballast of the power supply system are arranged on the inner wall of the shell above the fan; the input ends of the transformer and the ballast are connected with a vehicle-mounted power supply on a vehicle, and the output ends of the transformer and the ballast are connected with the positive poles of the plasma generating electrodes and the ultraviolet lamps; and the negative poles of the plasma generating electrodes are grounded. The vehicle-mounted air purifier can effectively clean pollutants in carriages.

Materials and Methods for photodirected synthesis of oligonucleotide arrays on a solid substrate by photodirected synthesis are disclosed which employ a film formed from (i) a photoacid generator that on photolysis generates acid that is capable of directly removing the protecting group of the linker molecules or oligonucleotides and (ii) a polymer substantially lacking electronegative heteroatoms that are capable of hydrogen bonding with photogenerated acid. Methods of synthesizing an oligomer arrays are also described that use a film that restricts diffusion of reactants and products on the substrate during synthesis of the array and which includes a precursor of a deprotecting reagent. The method involves removing one or more of the non-required products of the deprotection reaction from the reactive array elements at which they are produced during the reaction, in order to displace the deprotection reaction towards completion.

An improved BRET assay, wherein the BRET signal is enhanced and/or prolonged. The improved BRET assay comprises the steps of i) adding a substrate to a cell comprising GPCR-Rluc fusion protein and a β-arrestin-GFP fusion protein, wherein the (β-arrestin is mutated, ii) adding a ligand to obtain, if possible, a GPCR-Rluc/(β-arrestin-GFP complex, and iii) measuring a BRET signal to obtain a BRET ratio, wherein the improvement leads to an increased BRET ratio compared with the ratios obtained by use of the same process employing a β-arrestin-GFP fusion protein wherein the β-arrestin is the wild type β-arrestin, or employing a 13-arrestin-GFP fusion protein, wherein the (β-arrestin is a β-arrestin specifically mutated so that it acts on the receptor independent of the receptors phosphorylation state. The invention further relates to a stable substrate solution for use in an improved BRET assay.

The invention discloses a preparation method of a compound emulsifier in-situ crosslinking chitosan quaternary ammonium salt essential oil microcapsule. A compound emulsifier which has the dual functions of an emulsifier and a cross-linking agent is prepared through double hydroformylation modification on polyethylene glycol; in the preparation process of the chitosan quaternary ammonium salt essential oil microcapsule, on one hand, essential oil is emulsified by a polyethylene glycol long carbon chain structure in the compound emulsifier, on the other hand, chitosan quaternary ammonium salt crosslinking is conducted through a condensation reaction between aldehyde groups at the two ends of the compound emulsifier and amino groups on the chitosan quaternary ammonium salt, and then synchronization of the essential oil emulsifying process and the chitosan quaternary ammonium salt crosslinking process is achieved. According to the preparation method, by grafting aldehyde molecules achieving the chitosan quaternary ammonium salt crosslinking function onto polyethylene glycol, freeing of micromolecular aldehyde in the essential oil microcapsule preparation process is avoided, therefore, the content of micromolecular aldehyde in the essential oil microcapsule product is decreased, and the toxicity of the product is lowered.

The preparation process of sintered porous titanium artificial bone with bioceramic coating belongs to the field of biomedicine engineering technology. The preparation process includes stereo weaving of titanium metal fiber to form bionic structure model simulating human body's bone trabecula, pre-pressing formation and vacuum sintering to prepare porous titanium artificial bone, sol-gel process to form gradient and composite coating on the surface of the porous titanium artificial bone. The present invention can protect titanium metal skeleton, avoid titanium ion dissociation and make the artificial bone possess biological characteristic, and may be used in the clinical repair of large bone defect.

The invention relates to a biological microglia comprising at least two pores having a size adopted to allow cells, cell aggregates, tissue or other biological material to pass through said pores, and one or several slicing beams separating said pores from each other, wherein biological material is split/sliced/cleaved into at least two parts when passing said microgrid, a slicing device, an apparatus comprising said slicing device as well as the use of said microgrid, slicing device and apparatus.

The invention discloses an intraoperative branched on-demand block stent type artificial blood vessel system and a use method. The intraoperative branched on-demand block stent type artificial blood vessel system comprises an artificial blood vessel main body, a branched covered stent, a branched blocking device and a releasing device, wherein the branched blocking device is positioned around a joint between the artificial blood vessel main body and the branched covered stent or positioned in the cavity of the branched covered stent; the branched blocking device is separably connected with the artificial blood vessel or the branched covered stent, so that communication control between aortic vascular and branch vessels can be realized. By using the intraoperative branched on-demand block stent type artificial blood vessel system and the use method, the blocking and communication of the aortic vascular and the branch vessels on an aortic arch can be controlled as required, the dissociation, blocking or fitting and the like of the branch vessels on the arch is reduced or avoided, surgical operation is simplified greatly, and injury of blood vessels and peripheral tissues are reduced.

An edible spoon for dissociating into consumable predetermined clumps in order to prevent dissociating into random granules that would make consumption more difficult. The edible spoon includes a bowl and a handle. The bowl extends from the handle and contains weakened lines. The weakened lines in the bowl define the consumable predetermined clumps so as to allow the bowl to dissociate into the consumable predetermined clumps in order to prevent dissociating into the random granules that would make the consumption more difficult.

Disclosed herein are compounds and compositions thereof which find use in increasing stability of proteins particularly proteins that tend to misfold and form aggregates. Also provided herein are methods for using these compounds and compositions for increasing stability of proteins and thereby decreasing aggregate formation by these proteins. Also disclosed herein are heterobifunctional compounds that include a TTR binding compound connected to a targeting moiety via a linker, for use in disrupting PPIs of a target protein.

The invention relates to a polyether-loaded N-heterocyclic carbene-palladium compound and a preparation method and application thereof, belonging to the field of organic synthesis. For the polyether-loaded N-heterocyclic carbene-palladium compound, polyether molecular chains contain chain links (I): n in the chain links (I) is equal to 1-10, R is aryl or alkyl, and X is Cl-, Br-, I-, BF4- or PF6-. Compared with polyvinyl benzene, the polyether compound has good main chain flexibility and adjustable branched chain length, and can be used for loading a catalyst to enable the catalyst to maintain higher catalytic activity and enable polymers containing polyepichlorohydin chain links, N-hydroxyl-substituted imidazolium, alkali and palladium salts to react to prepare the compound. The invention also provides the application of the compound: the compound is used for catalyzing substituting reaction of aromatic compounds Aryl-X' and alpha-H contained carboxylic ester to synthesize alpha-aryl carboxylic ester by one-step catalysis, and has mild reaction condition, high yield, good economic benefit and important application value.

The invention discloses an antharcycline antitumor antibiotics loaded nano-micelle preparation, which comprises antharcycline antitumor antibiotics, A-B-C type triblock polymer and assisting agents, wherein the antharcycline antitumor antibiotics is one or more of adriamycin, daunorubicin, pharmorubicin, perarubicin or lacinomycin; and the A-B-C type triblock polymer is polyethylene glycol-polyethylene glycol containing carboxyl on side chain-polyester. According to the preparation, drugs are coated in the nano-micelle by virtue of the coaction of self-assembly of segmented copolymer and electrostatic adsorption, the nano-micelle has uniform and stable grain diameter, the encapsulation efficiency reaches 99 percent, and the prepared nano-micelle preparation is of a spherical structure with grain diameter between 20 and 300nm; and the shell of the micelle is made from polyethylene glycol molecules, so that drugs are prevented from being contacted with enzyme and other protein molecules in blood or identified and swallowed by a reticuloendothelial system in the body, so that the circulating period of micelle in the body can be prolonged.

The invention relates to the technical field of display, and discloses a display panel and a preparation method thereof and a display device. The display panel comprises a first substrate, a second substrate and at least one spacer, wherein the first substrate and the second substrate are arranged in a combined manner, the spacers are positioned between the first and second substrates, the second substrate is provided with an alignment layer facing to the first substrate, the alignment layer is provided with recesses corresponding to all the spacers, and each spacer is fixed on the first substrate and butted in the corresponding recess. Since the alignment layer is provided with the recesses corresponding to the spaces and each spacer is butted in the corresponding recess, even the display panel generates alignment layer chips or spacer chips due to external force, the chips are retained in the recesses, and probability of diffusing to a display region is lowered; therefore, fine bright spots on the display panel are decreased, and further image quality of the display panel is improved.

The invention belongs to the technical field of sewage treatment, discloses an ammonia nitrogen removal bacterium agent, and aims to provide an ammonia nitrogen removal bacterium agent which is high in ammonia nitrogen removal efficiency and can recycle bacterium removal agents and fillers. The technical scheme includes that compound bacterium agents are cured on the fillers and comprise heterotrophic nitrification bacteria, bacillus and denitrifying bacteria.