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Intestinal flora reestablishment kit and application thereof

A technology of intestinal flora and kit, which is applied in the directions of feeding oral medicines, packaged food, packaging, etc., can solve the problem of unclear active ingredients of donor feces, complicated preparation and transplantation operations, uncontrollable fecal flora transplantation, etc. problems, to avoid mistakes or unreasonable use, fast re-establishment, and high security

Active Publication Date: 2019-02-05
HEBEI UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sample preparation and transplantation operations for fecal microbiota transplantation are cumbersome, and oral fecal microbiota capsules are poorly accepted by patients, while other methods are painful for patients and costly
Moreover, because the active ingredients of donor feces are not clear, fecal microbiota transplantation brings uncontrollable risks
At present, there is no safe, efficient, and easy-to-accept method that can change the intestinal flora.

Method used

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  • Intestinal flora reestablishment kit and application thereof
  • Intestinal flora reestablishment kit and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] The method for using the intestinal flora reconstruction kit in the process of intestinal flora reconstruction comprises the following steps:

[0063] 1) Day 1: For lunch and dinner, eat liquid food and non-dregs food, such as soft rotten bean porridge or oatmeal porridge, custard, rye noodles, soy milk, etc. until you are 70 to 80% full.

[0064] 2) Day 2:

[0065] a: Breakfast: Before meals, take the compound polyethylene glycol or mannitol injection in the nth chamber of the kit orally for intestinal lavage. After the colon lavage is completed, start to eat after emptying the intestinal tract. Eat an appropriate amount of liquid food and cook until soft. Rotten and less oily vegetables until 70% full, within 0.5-1h after the meal, open the n+1th chamber and take the probiotics of group A and group B in the chamber orally, so as to use the probiotics of group A Quickly consume the oxygen in the intestinal tract after colon lavage, and then take the probiotics of grou...

Embodiment 2

[0080] Application of gut microbiota reconstitution kit in gut microbiota reconstitution in patients with ankylosing spondylitis and rheumatoid.

[0081] Cao, male, 45 years old, Baoding, Hebei, suffered from ankylosing spondylitis, combined iritis, and bad breath for more than 3 years, and usually took Tripterygium wilfordii and other drugs for treatment.

[0082] On March 1, 2018, intestinal flora reconstruction began according to the use method of the intestinal flora reconstruction kit in Example 1 of the present invention, and the spinal pain was relieved on the second day after use, and the original bad breath disappeared; All the drugs I had been taking were stopped for four days, and there was a slight pain in the spine, but it was milder than when I took the medicine before the intestinal flora reconstruction, and the iritis was significantly relieved; on the seventh day of the intestinal flora reconstruction, the iritis was cured, and all joints moved freely. , no mo...

Embodiment 3

[0086] Application of intestinal flora reconstruction kit in the reconstruction of intestinal flora in patients with ankylosing spondylitis and rheumatoid

[0087] Gao, male, 32 years old, from Shijiazhuang, Hebei Province, suffered from rheumatoid arthritis for more than 2 years. He suffered from wind and cold joint pain and discomfort, and his right knee joint was obviously bent. He was usually treated with various drugs such as penicillamine and Pavlin.

[0088] On December 25, 2017, the intestinal flora reconstruction kit in Example 1 was used to rebuild the intestinal flora. In the first two days, I took the previous treatment medicine in the morning and evening, and the joint pain was relieved after being exposed to the wind and cold. ; On December 27, the joint pain was not obvious, and he did not sweat at night, and there was no obvious wind-piercing feeling in the joints; after that, all the drugs were stopped, and the joints were slightly uncomfortable due to the wind...

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Abstract

The invention discloses an intestinal flora reestablishment kit. The kit comprises a kit body; the kit body comprises multiple cavities which are sequentially and regularly opened, the cavities are from the n th cavity to the (n+x) th cavity according to the opening sequence, and the time interval of opening time of adjacent cavities from the n th cavity to the (n+x) th cavity is 4-12 h; the n thcavity comprises compound polyethylene glycol electrolyte powder or mannitol injection, the (n+1) th cavity comprises A and B microecologics, the (n+2) th cavity comprises B microecologics, the cavities from the (n+3) th cavity to the (n+21) th cavity comprise B and A microecologics, and the cavities from the (n+22) th cavity to the (n+x) th cavity comprise B microecologics. Through intestinal lavage and sequential taking of different preparations, quick reestablishment of the intestinal flora is facilitated. The invention further discloses application of the kit to reestablishment of ankylosing spondylitis and rheumatoid intestinal florae. Through the reestablishment of the intestinal flora, arthralgia of a patient is relieved, joints move freely, so that the kit is feasible in the aspectof relieving arthralgia and discomfort of the patient.

Description

technical field [0001] The invention relates to the technical field of general health, more specifically, the invention relates to a kit for rebuilding intestinal flora and its application. Background technique [0002] The intestinal tract is the largest organ for digestion, absorption and excretion of the human body. More than 90% of the nutrients and metabolic waste in the human body are absorbed and excreted through the intestinal tract. In addition to the intestinal tract itself, there are more than 1,500 kinds of microorganisms living in the intestinal tract, which are 10 times the number of human cells. These microorganisms are mainly bacteria, forming an extremely complex group, which is the intestinal flora. A healthy intestinal flora is combined in a certain proportion. Various bacteria restrict and depend on each other. They have a symbiotic relationship with the host and jointly maintain the physiological homeostasis of the host. [0003] The establishment of th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J7/00A61J1/00
CPCA61J1/00A61J7/00
Inventor 吕志堂
Owner HEBEI UNIVERSITY
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