Compound transdermal-absorption traditional Chinese medicine ointment as well as preparation method and application thereof

A traditional Chinese medicine ointment and transdermal technology, which is applied in the directions of ointment delivery, drug combination, pharmaceutical formulation, etc., can solve problems such as rare reports, and achieve the effects of being beneficial to industrial production, stable in nature and accurate in effect.

Inactive Publication Date: 2015-01-07
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There have been reports on the mechanism of penetration enhancers promoting drug transdermal absorption in the field of medicine at home and abroad, but few reports in the field of veterinary medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A compound transdermal absorption traditional Chinese medicine ointment is prepared from the following components: 3 g of Coptis chinensis extract, 1.8 g of Scutellaria baicalensis extract, 3 g of Salvia miltiorrhiza extract, 1.8 g of wintergreen extract, 55 g of vaseline, and 1.5 g of azone. In the Coptidis Rhizoma extract, the mass percentage of berberine determined by high performance liquid chromatography is 10%; in the Scutellaria baicalensis extract, the mass percentage of baicalin determined by high performance liquid chromatography is 20%; In the salvia miltiorrhiza extract, the mass percentage of tanshinone IIA determined by high performance liquid chromatography is 1%; in the wintergreen extract, the mass percentage of wintergreen is determined by high performance liquid chromatography 5%.

[0038] The preparation method of above-mentioned a kind of compound transdermal absorption Chinese medicinal ointment, comprises the following steps:

[0039] 1) Under st...

Embodiment 2

[0042] The specific embodiment is the same as Example 1, the difference is that a compound transdermal absorption traditional Chinese medicine ointment is prepared from the following components: Coptis chinensis extract 4g, Scutellaria baicalensis extract 2.2g, Salvia miltiorrhiza extract 4g, deer trotter Grass extract 2.8g, petrolatum 75g, azone 2.5g.

Embodiment 3

[0044] The specific embodiment is the same as Example 1, the difference is that a compound transdermal absorption traditional Chinese medicine ointment is prepared from the following components: Coptis chinensis extract 3g, Scutellaria baicalensis extract 1.8g, Salvia miltiorrhiza extract 3g, deer trotter Grass extract 1.8g, petrolatum 65g, azone 1.5g.

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PUM

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Abstract

The invention discloses a compound transdermal-absorption traditional Chinese medicine ointment. The compound transdermal-absorption traditional Chinese medicine ointment is prepared from the following components in parts by weight: 3 parts of coptis chinensis extract, 1.8 parts of scutellaria baicalensis extract, 3 parts of red-rooted salvia root extract, 1.8 parts of pyrola rotundifolia extract, 55-75 parts of vaseline and 1.5-2.5 parts of azone. The invention also provides a preparation method and application of the compound transdermal-absorption traditional Chinese medicine ointment. The compound transdermal-absorption traditional Chinese medicine ointment has the beneficial effects as follows: firstly, the traditional Chinese medicine ointment can be used for effectively treating bovine mastitis, has good effects of clearing away heat and toxic materials, preventing bacteria and diminishing inflammation and promoting blood circulation to remove blood stasis, is free of any chemical component due to adoption of pure traditional Chinese medicine preparation and is beneficial to safety of dairy products; secondly, the stable transdermal-absorption traditional Chinese medicine ointment is obtained by virtue of an ointment machine, and is stable in property and controllable in quality, and very beneficial to industrial production; and thirdly, as a drug for effectively treating bovine mastitis, the compound transdermal-absorption traditional Chinese medicine ointment is exact in effect, free of residues and toxic and side effect, capable of being used during a lactation period and capable of becoming a good substitute of antibiotics.

Description

[0001] technical field [0002] The invention relates to the field of veterinary medicine, in particular to a compound transdermal absorption traditional Chinese medicine ointment and its preparation method and application. Background technique [0003] Dairy mastitis is an inflammation of the mammary glands of dairy cows, which is caused by a variety of injuries, such as pathogenic microorganisms. It is one of the most harmful, common and economically damaging diseases in dairy farms. Although there have been many years of research, the effect of its control is still not obvious. At present, there are about 230 million dairy cows in the world, about 1 / 3 of which suffer from various types of mastitis, and the positive rate of mastitis is 48.2 %-69.7%, and the positive rate in breast area was 31%-51.2%. According to surveys in Beijing, Shanghai, Guangzhou, Xi'an, Lanzhou and other cities, the incidence rate of mastitis is 20% to 70%, the positive rate of dairy cow recessive ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K36/898A61K9/06A61P15/14
CPCA61K36/718A61K9/06A61K36/185A61K36/537A61K36/539A61K36/704A61K36/71A61K36/898
Inventor 梁剑平郝宝成郭文柱刘宇尚若锋王学红郭志廷陶蕾赵凤舞贾忠
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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