A kind of graphene oxide imitating cell outer membrane structure modification and preparation method thereof

A technology of imitating cell outer layer membrane and graphene is applied in the field of graphene oxide modified by imitating cell outer layer membrane structure and its preparation field, and achieves the effects of excellent biocompatibility, simple preparation method and broad application prospect.
CN104258471BInactive Publication Date: 2016-09-07XIAN UNIV OF SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
XIAN UNIV OF SCI & TECH
Publication Date
2016-09-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a graphene oxide imitating the structure modification of the outer membrane of cells and a preparation method thereof, which is synthesized by a free radical polymerization method through vinyl monomers containing zwitterionic hydrophilic groups and vinyl monomers containing amino groups Binary random copolymers of - a zwitterionic polymer containing amino groups, grafting zwitterionic polymers containing amino groups onto the surface of graphene oxide can obtain graphite oxide with excellent biocompatibility imitating the structure of the outer membrane of cells Alkene, to avoid the residue of the initiator. The preparation method of the modified graphene oxide imitating cell outer membrane structure of the present invention is simple, the conditions are mild, and the post-treatment is simple, which provides a new way for obtaining a stable imitating cell outer membrane structure on the surface of graphene oxide , the graphene oxide modified with the imitation cell outer membrane structure will have broad application prospects in the fields of implant materials in vivo, tissue engineering, drug sustained release and biosensors.
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Description

technical field

[0001] The invention belongs to the technical fields of material surface science and biomedical polymer materials, and in particular relates to a graphene oxide imitating the structure modification of the outer membrane of cells and a preparation method thereof. Background technique

[0002] When the material is used in a living body, it is easy to non-specifically adsorb proteins, activate complement molecules and the immune system, thereby causing blood coagulation, immune and inflammatory reactions, resulting in a significant decrease in its performance or even failure. This is due to the poor biocompatibility of materials, therefore, biocompatibility research has become the primary issue in the field of biomaterial research. The surface of a material is the medium through which the material contacts the organism. Surface charge, hydrophilicity / hydrophobicity, chemical composition, and morphology are important factors that affect the interface interaction ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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