Ceramide and/or glucosylceramide generating accelerant or humectant

A technology of ceramide and glucose, applied in skin care preparations, food science, cosmetics and other directions, can solve the problems of increased manufacturing cost and high price, and achieve the effect of improving capacity, low price, and improving moisturizing function.

Inactive Publication Date: 2015-02-11
KAO CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the high price of these plant raw materials, the production cost of the ceramide production accelerator will also increase accordingly, so that cheaper raw materials are desired
However, there is no report about the effect of black tea on ceramide production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] (1) Manufacture of black tea extract Add 10 times the quality of petroleum ether to 20 grams of black brick tea, stir and extract at 63-65°C for 30 minutes, repeat this extraction three times, filter and separate the residue, and recover the petroleum ether extract .

[0070] Next, for the residue obtained in the petroleum ether extraction process, after volatilizing the petroleum ether remaining in the residue at room temperature, add 10 times the mass (volume ratio) of water, stir and extract at 80-85°C for 30 minutes, and repeat 2 such extractions. The residue and aqueous extract were separated by filtration. Concentrate the water extract under reduced pressure at 60°C, set the volume to 100ml of water concentrate, add 400ml of 100% ethanol to make an 80% ethanol solution, stir for 20 minutes, and then centrifuge after standing at 4°C. The ethanol extract and precipitate were separated by filtration. The separated precipitate is vacuum-dried to obtain the water ex...

Embodiment 2

[0110] Use the seven sub-grade Pu'er tea as black tea, obtain the extract of the seven sub-grade Pu'er tea by the same manufacturing method as in Example 1, dissolve the extract in 10v / v% ethanol, and adjust it to 1% (w / v) After concentration, the same ceramide and / or glucosylceramide production promotion test as in Example 1 was carried out to evaluate the ceramide and / or glucosylceramide production promotion effect of the extract, and the results are shown in Table 6.

[0111] Table 6

[0112]

[0113] As shown in Table 6, the seven sub-grade Pu-erh tea extracts showed significant ceramide and glucosylceramide production-promoting effects.

Embodiment 3

[0115] Using Laote Pu'er tea as black tea, the extract of Laote Pu'er tea was obtained by the same manufacturing method as in Example 1, and the extract was dissolved in 10v / v% ethanol to adjust to 0.1% (w / v) After concentration, the same ceramide and / or glucosylceramide production promotion test as in Example 1 was carried out to evaluate the ceramide and / or glucosylceramide production promotion effect of the extract, and the results are shown in Table 7.

[0116] Table 7

[0117]

[0118] As shown in Table 7, the old tea extracts showed significant ceramide and glucosylceramide production-promoting effects.

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PUM

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Abstract

The invention provides a geramide and/or glucosylceramide generating accelerant or humectant. The geramide and/or glucosylceramide generating accelerant or humectant takes black tea extracts selected from more than one of black brick tea, compressed tea after fermentation and Pu'er tea as effective components.

Description

technical field [0001] The present invention relates to a ceramide and / or glucosylceramide production accelerator or a moisturizing agent. Background technique [0002] Ceramide, one of the sphingolipids, exists in the stratum corneum of the skin and accounts for about 50% of the intercellular lipids in the stratum corneum. Sphingolipid is a general term for complex lipids having a sphingosine skeleton. Glucosylceramide is a kind of sphingolipid formed by binding glucose to ceramide. The ceramide synthesized by epidermal cells is temporarily stored in the form of glucosylceramide or sphingomyelin; it is then excreted out of the cell, where β-glucocerebrosidase (β-Glucocerebrosidase, also known as glucoside) Under the action of enzymes β-glucosidase and sphingomyelinase, it becomes ceramide again, thereby functioning as an intercellular lipid. [0003] Conventionally, it has been known that sphingolipids such as ceramide, glucosylceramide, and galactosylceramide have effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A23L1/30A61Q19/00A23L33/105
Inventor 裘桂潇
Owner KAO CORP
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