Pharmaceutical composition for treating and preventing depression and preparation method of pharmaceutical composition

A composition and technology for depression, which can be used in drug combinations, pharmaceutical formulations, and medical preparations without active ingredients, etc., and can solve problems such as difficult quality control, unclear active ingredients, and complex composition.
CN104490972AInactive Publication Date: 2015-04-08SHANXI UNIV

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHANXI UNIV
Publication Date
2015-04-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a pharmaceutical composition for treating and preventing depression and a preparation method of the pharmaceutical composition. The composition consists of radix bupleuri extract, Chinese angelica extract and white atractylodes rhizome extract. According to the pharmacological experiment results, the pharmaceutical composition can be used for obviously reducing dead time in a mouse forced swimming test and a mice hanging test, remarkably increasing chronic temperature and the weight and the sweet water eccentricity of an unpredictable depression model, and has an obvious anti-depression effect which can reach or exceed that of the existing clinical common anti-depression drugs.
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Description

technical field

[0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating and preventing depression, a preparation method and application thereof. Background technique

[0002] Depression is a mental disease that seriously endangers human health. After the illness, the main manifestations are depression, loss of interest, slow thinking, lack of initiative, pessimistic attitude towards things, anorexia, insomnia, and even suicide in severe cases. Moreover, depression has the characteristics of high incidence rate, high recurrence rate, and high disability rate. The incidence rate in my country is 2.5%, and the number of patients exceeds 30 million.

[0003] At present, the drugs used to treat depression are mainly chemical drugs. For example, the "five golden flowers" that are called antidepressants by the psychiatric circles in my country are: fluoxetine (Prozac), paroxetine ( Sertraline), sertraline (Zoloft), f...

Claims

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