Pharmaceutical composition for treating depression and preparation method and application thereof

The technology of a composition and medicine is applied in the field of pharmaceutical compositions for the treatment of depression, and can solve the problems of slow onset, high price and the like

Active Publication Date: 2021-02-26
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western antidepressants often have problems with tolerance and safety, are expensive, have slow onset, and require long-term use

Method used

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  • Pharmaceutical composition for treating depression and preparation method and application thereof
  • Pharmaceutical composition for treating depression and preparation method and application thereof
  • Pharmaceutical composition for treating depression and preparation method and application thereof

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Embodiment Construction

[0026] In order to facilitate understanding of the present invention, the present invention will be described more fully below with reference to various embodiments, however, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that the disclosure of the present invention will be thorough and complete.

[0027] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the technical field of the invention. The terms used herein in the description of the present invention are for the purpose of describing specific embodiments only, and are not intended to limit the present invention. As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items.

[0028] (1) The dosage form of the pharmaceutical composition is a granule, and the pre...

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PUM

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Abstract

The invention provides a pharmaceutical composition for treating depression and a preparation method and application thereof. The pharmaceutical composition comprises the active pharmaceutical ingredients, by weight, 80-150 parts of rhizoma cyperi, 80-150 parts of cardamom, 80-150 parts of mint, 80-120 parts of fennel, 60-100 parts of radix bupleuri, 30-80 parts of selfheal, 80-120 parts of humifuse euphorbia herb, 120-200 parts of liquorice, 100-150 parts of Chinese date, 50-100 parts of spina date seed, 30-50 parts of cortex albiziae and 60-100 parts of myrobalan. A rat chronic mild unpredictable stress model, a rat olfactory bulb excision model, a mouse behavior despiring model and a 5-hydroxytryptophan induced mouse head shaking behavior model prove that the pharmaceutical compositionhas an anti-depression effect, in addition, the pharmaceutical composition can be prepared into tablets, pills, granules, syrups and capsules through a conventional method, and the preparation methodis simple, safe, economical and effective.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical compositions, in particular to a pharmaceutical composition, preparation method and application for treating depression. Background technique [0002] Depression is a type of mood disorder characterized by significant and persistent low mood, slow thinking, cognitive impairment, and attenuation of volitional activity. Other common symptoms include decreased self-evaluation, self-guilt and worthlessness (even in mild episodes), bleak and pessimistic views about the future, self-injury or suicide ideas or behaviors, sleep disturbances, decreased appetite, etc., and the course of the disease continues At least 2 weeks. Depression will not only damage the patient's health and lead to a decline in the quality of life, but also cause a great burden on the family and society. At present, depression has become a serious social and medical problem. [0003] The etiology of depression is still uncl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P25/24
CPCA61K36/8905A61K36/9064A61K36/534A61K36/235A61K36/725A61K36/48A61K36/185A61K36/233A61K36/536A61K36/47A61K36/484A61P25/24A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 张国松李东勲张文锍雷志强胡鹏翼夏明艳魏鑫华贾超
Owner JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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