Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Pharmaceutical composition for treatment of qi-blood deficiency, irregular menstruation, metrorrhagia and leukorrheal diseases and preparation method thereof

A technology of qi and blood deficiency and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., and can solve the problems of complex process and low extraction rate

Active Publication Date: 2015-07-01
津药达仁堂集团股份有限公司乐仁堂制药厂
View PDF4 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, the above-mentioned methods generally have various problems such as complicated process and low extraction rate. In order to improve the deficiencies in the prior art, the present invention starts with the extraction process and studies the extraction method of Wuji Baifeng preparation, and obtains a Extraction method of new Wuji Baifeng preparation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pharmaceutical composition for treatment of qi-blood deficiency, irregular menstruation, metrorrhagia and leukorrheal diseases and preparation method thereof
  • Pharmaceutical composition for treatment of qi-blood deficiency, irregular menstruation, metrorrhagia and leukorrheal diseases and preparation method thereof
  • Pharmaceutical composition for treatment of qi-blood deficiency, irregular menstruation, metrorrhagia and leukorrheal diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0158] Take medicinal materials by weight as follows:

[0159]

[0160] (1) Cut the black-bone chicken without hairy claw intestines into pieces, add 3 times the amount of water, boil for 2 hours, degrease with 10:1 solid paraffin while hot, then add 150:1 papain and stir to adjust the pH value to 6, After hydrolyzing for 4 hours at 50°C, boil for 20 minutes, centrifuge, concentrate the supernatant under reduced pressure, the relative density is 1.02-1.32 at 60°C, and set aside;

[0161] (2) Add Cyperi Cyperi, Angelica, and Rhizoma Chuanxiong to 5 times the amount of water, heat to boiling, extract the volatile oil until the oil is extracted, and set aside the volatile oil. The water extract in the process of extracting the volatile oil is concentrated into an extract (measured at a relative density of 65°C). 1.13~1.17):

[0162](3) Add 4 times the amount of Danshen and Ginseng to 85% ethanol to extract 3 times, each time for 1 hour, combine the extracts, filter, recover t...

Embodiment 2

[0167] Take medicinal materials by weight as follows:

[0168]

[0169] (1) Cut the black-bone chicken without hairy claw intestines into pieces, add 2 times the amount of water, boil for 4 hours, degrease with 15:1 solid paraffin while hot, then add 260:1 papain and stir to adjust the pH value to 8, After hydrolysis at 65°C for 3 hours, boil for 20 minutes, centrifuge, concentrate the supernatant under reduced pressure, and measure the relative density at 60°C to be 1.02-1.32, set aside;

[0170] (2) Add Cyperi Cyperi, Angelica, and Rhizoma Chuanxiong to 8 times the amount of water, heat to boiling, extract the volatile oil until the oil is extracted, and set aside the volatile oil. The water extract in the process of extracting the volatile oil is concentrated into an extract (measured at a relative density of 65°C). 1.13~1.17);

[0171] (3) Add 4 times the amount of salvia miltiorrhiza and ginseng to 95% 7 alcohol to extract 4 times, 2 hours each time, combine the extra...

Embodiment 3

[0176] Take medicinal materials by weight as follows:

[0177]

[0178] (1) Cut the black-bone chicken without hairy claw intestines into pieces, add 5 times the amount of water, boil for 0.5 hours, degrease with 5:1 solid paraffin while hot, then add 80:1 papain and stir to adjust the pH value to 4, After hydrolysis at 40°C for 8 hours, boil for 5 minutes, centrifuge, and concentrate the supernatant under reduced pressure, the relative density is 1.02-1.32 at 60°C, and set aside;

[0179] (2) Add Cyperi Cyperi, Angelica, and Rhizoma Chuanxiong to 4 times the amount of water, heat to boiling, extract the volatile oil until the oil is extracted, and set aside the volatile oil. The water extract in the process of extracting the volatile oil is concentrated into an extract (measured at a relative density of 65°C). 1.13~1.17);

[0180] (3) Add 3 times the amount of salvia miltiorrhiza and ginseng to extract 50% ethanol for 5 times, each time for 1 hour, combine the extracts, f...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pharmaceutical composition, in particular to a pharmaceutical composition for treatment of qi-blood deficiency, irregular menstruation, metrorrhagia and leukorrheal diseases and a preparation method thereof. The pharmaceutical composition contains 20 crude drugs: unhaired, declawed and intestine removed silky fowl, Salvia Miltiorrhiza, calcined oyster, cornu cervi degelatinatum, astragalus and the like. The preparation method includes: (1) conducting enzymolysis extraction on silky fowl to obtain an extracted liquid; (2) extracting volatile oil from cyperus rotundus, Chinese angelica and Ligusticum wallichii for standby use, and concentrating the water extracted liquid obtained in the volatile oil extraction process into an extract; (3) subjecting Salvia Miltiorrhiza and ginseng to alcohol extraction and water precipitation to obtain an alcohol extract, and performing concentration to obtain an extract; (4) subjecting the extracted herb residue in step (3) and radix paeoniae alba, radix asparagi, astragalus, Radix Stellariae, rehmannia root, prepared rehmannia root, Euryale ferox, Chinese yam, licorice, turtle shell and Mantis Egg-case together to water extraction and alcohol precipitation, concentrating the obtained extracted liquid and the silky fowl extracted liquid obtained in step (1) together into an extract; (5) carrying out superfine pulverization on deer-horn glue, cornu cervi degelatinatum and oyster; and (6) mixing and pulverizing the extracts obtained in step (2), (3) and (4) with the superfine pulverized powder, and spraying the volatile oil in step (2) so as to obtain the pharmaceutical composition.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating qi and blood deficiency, irregular menstruation and metrorrhagia and a preparation method thereof. Background technique [0002] The black-bone chicken and white phoenix slices are made according to the addition and subtraction of the "black-bone chicken ball" in Volume 7 of Ming Gong Tingxian's "Shou Shi Bao Yuan". It was later recorded in the "Pharmacopoeia of the People's Republic of China". At present, there are mainly two kinds of twelve herbs and twenty herbs. Twelve herbs include black-bone chicken (hairless claw sausage), salvia, rehmannia glutinosa, Cyperus cyperi (made from vinegar), ginseng, white peony root, oyster (calcined), antler cream, silver bupleurum, licorice, astragalus, turtle shell (made) . Twenty flavors of medicinal materials are added on the basis of twelve, antler gum, mulberry octopus, angelica, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61P15/00A61K35/32A61K35/57A61K35/586A61K35/618A61K35/64
Inventor 王磊金兆祥王琳张宇
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com