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Extracting method for plant composition containing valeriana officinalis and application

An extraction method and composition technology, which is applied in the field of extracting plant compositions containing valerian, can solve the problems of large dosage for patients, rough process, and many impurities, and achieve the effect of reducing dosage

Inactive Publication Date: 2015-12-09
南京多宝生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing valerian. However, the method of decocting in water is rough and backward, and there are many impurities, which leads to excessive dosage for patients and is inconvenient to take. Seriously affected the clinical application of this product

Method used

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  • Extracting method for plant composition containing valeriana officinalis and application
  • Extracting method for plant composition containing valeriana officinalis and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take 100g of valerian, 60g of variegated leaves, 50g of variegated leaves, 70g of horse willow root, and 150g of purple pearl leaves, pulverize them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, extract 2 4-8 minutes each time, combine the extracts, concentrate, add to the D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry, The microwave extract was obtained, and conventional excipients were added to prepare tablets, each tablet 0.4g.

Embodiment 2

[0016] Take 100g of valerian, 60g of variegated leaves, 50g of variegated leaves, 70g of horse willow root, and 150g of purple pearl leaves, pulverize them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, extract 2 4-8 minutes each time, combine the extracts, concentrate, add to the D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry, The microwave extract is obtained, and conventional auxiliary materials are added to prepare capsules.

Embodiment 3

[0018] Take 100g of valerian, 60g of variegated leaves, 50g of variegated leaves, 70g of horse willow root, and 150g of purple pearl leaves, pulverize them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W, extract 2 4-8 minutes each time, combine the extracts, concentrate, add to the D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry, The microwave extract is obtained, and conventional auxiliary materials are added to prepare granules.

[0019] Variegated leaf is the whole plant of Vitis variegated leaf, which has the functions of dispelling wind and detoxification, reducing swelling and blood stasis, and reconnecting bones and tendons. Treatment of urticaria, eczema, allergic dermatitis, fractures and tendon injuries, bruises, sprains, rheumatic numbness and other effects.

[002...

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Abstract

The invention provides an extracting method for a plant composition containing valeriana officinalis. The plant composition is prepared with 100 g of the valeriana officinalis, 60 g of cissus javana, 50 g of coprinopsis atramentaria, 70 g of salix cheilophila roots and 150 g of callicarpa macrophylla leaves as raw medicinal materials. Preparing is carried out with a microwave extraction method, so that the content is greatly increased, and use amount is reduced. The invention further provides an application of the plant composition containing the valeriana officinalis in preparing medicine for inhibiting mice fibroblast L929 cell proliferation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing valerian. Background technique [0002] The plant composition containing valerian is made of 100g of valerian, 60g of variegated leaves, 50g of ghost caps, 70g of horse willow roots, and 150g of purple pearl leaves as raw materials. The current extraction method is to add water and decoct twice, each time 2- After 3 hours, the decoctions were combined, filtered, concentrated into a thick paste, granulated, dried, pressed into 1000 tablets, coated with sugar, and ready to use. It can clear away heat and detoxify. [0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing valerian root, but the method of decocting in water is rough, backward, and has many impurities, which leads to excessive...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61P35/00
Inventor 李洋
Owner 南京多宝生物科技有限公司
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