Complex hernia patch and preparing method and application thereof

Abstract

The invention provides a complex hernia patch and a preparing method and application thereof. The complex hernia patch comprises three layer structures which are an outer biological layer, an inner supporting layer and an outer biological layer from bottom to top respectively, wherein the outer biological layers are accellular stent layers, and the inner supporting layer is a polypropylene mesh layer. The complex hernia patch prepared through the preparing method comprises the three layer structures, accellular stents in contact with tissue are located on the outer layers, cells can be induced to grow, and thus infection of a hernia coloboma part and formation of scars can be reduced; the polypropylene mesh layer serves as the inner supporting layer so that the mechanical strength of the complex hernia patch can be maintained, the stability of the patch can be improved, and high abdomen expansion pressure can be borne; furthermore, the binding force of the inner layer and the outer layers is good, and thus the problems that due to the fact that the strength of an existing product is not stable, high abdomen expansion pressure cannot be borne, a stent is gradually degraded after cells grow into the stent, consequently tardive pain of hernia repair is brought and relapse is likely to occur can be effectively solved; in addition, the preparing method is simple and capable of being applied to industrial production.

Description

technical field [0001] The invention belongs to the field of medicament preparation, and relates to a composite hernia patch, a preparation method and application thereof. Background technique [0002] Hernia repair patch is mainly used for the repair of abdominal wall hernia, which means that the organs or tissues in the abdominal cavity protrude from the weak area or defect of the abdominal wall. Abdominal wall hernia includes inguinal hernia, umbilical hernia, femoral hernia, incisional hernia and parastomal hernia, etc. Inguinal hernia (the junction of thigh and abdomen) is the most common. Because of the high incidence of abdominal wall hernia, its treatment has become an important social issue. [0003] Currently, hernia repair is the only option for healing abdominal wall hernias. Hernia repair refers to the surgical treatment of hernia, which can be divided into traditional hernia repair and hernia mesh tension-free repair. At present, tension-free repair has beco...

AI Technical Summary

Problems solved by technology

However, due to its unstable source, the strength of the final product is also unstable, and it is difficult to withstand high abdominal pressure. After the cells grow in, the scaffold will gradually degrade, so the recurrence rate is much higher than that of artificial synthetic patches.