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Antitumor oral liquid and preparation method thereof

An oral liquid and anti-tumor technology, applied in the field of anti-tumor oral liquid and its preparation, can solve the problems of slow effect and insignificant effect, and achieve the effects of sufficient extraction and improved therapeutic effect.

Inactive Publication Date: 2016-03-16
HEBEI UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine treats tumors as a whole, and the side effects are small. However, in the existing methods of treating tumors with traditional Chinese medicine, there are generally deficiencies such as slow effect and insignificant effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0030] A preparation method of an anti-tumor oral liquid, comprising the following steps: step 1, raw material drying and crushing to obtain a raw material powder; step 2, mixing and extracting the raw material powder with 10-40 times the volume of 60-80% ethanol to obtain an extract Step 3: Concentrate the extract to obtain a thick ointment, dilute the thick ointment with water 1-10 times, pack and seal it, and obtain the bitter vegetable oral liquid.

[0031] In the preparation method of the anti-tumor oral liquid, in step 2, the specific extraction method is: heating the mixture of the raw material powder and the ethanol solution to a slight boiling state and keeping it for 1-10 minutes, and then ultrasonically vibrating for 20 minutes after cooling to room temperature. -40 minutes to break the cells, dissolve the cell contents, and centrifuge to obtain the supernatant, which is the extract.

[0032] In the preparation method of the anti-tumor oral liquid, in step 3, the ex...

Embodiment 1

[0038] 1. Weigh 160 grams of bitter cabbage, 8 grams of Smilax smilax, 2 grams of Shanzi mushroom, 5 grams of wood butterfly bark, 10 grams of honeysuckle, 10 grams of dandelion, 8 grams of Houttuynia cordata, 5 grams of rhodiola rosea, and 2 grams of frankincense , 2 grams of myrrh, 2 grams of Ziweizi, 8 grams of drynaria, 2 grams of kelp, 2 grams of seaweed, 8 grams of corrugated seeds, 4 grams of Tinglizi fried, 18 grams of astragalus honey, 8 grams of heterophylla, white 8 grams of lentils, 8 grams of Wulingzhi, 1 gram of Cordyceps sinensis and 5 grams of psoralen, dried and crushed to obtain 240 grams of raw material powder, mixed with 5000 mL of 70% ethanol solution, and heated to a slight boil for 3 minutes to make the raw material cells Fully rupture, so that the active ingredients in the raw materials can be fully dissolved.

[0039]2. After cooling to room temperature, centrifuge to separate the supernatant, and then ultrasonically assist extraction for 30 minutes, t...

Embodiment 2

[0042] 1. Weigh 180 grams of bitter cabbage, 10 grams of Smilax smilax, 3 grams of Arrowhead mushroom, 6 grams of wood butterfly bark, 12 grams of honeysuckle, 12 grams of dandelion, 9 grams of Houttuynia cordata, 6 grams of Rhodiola rosea, and 3 grams of frankincense , 3 grams of myrrh, 3 grams of fennel, 9 grams of Drynaria, 3 grams of kelp, 3 grams of seaweed, 9 grams of corrugated seeds, 5 grams of Tinglizi fried, 20 grams of Astragalus honey, 10 grams of Radix Pseudostellaria, white 10 grams of lentils, 10 grams of wulingzhi, 2 grams of Cordyceps sinensis and 6 grams of psoralen, dried and crushed to obtain 280 grams of raw material powder, mixed with 4000 mL of 75% ethanol solution, and heated to a slight boil for 5 minutes to make the raw material cells Fully rupture, so that the active ingredients in the raw materials can be fully dissolved.

[0043] 2. After cooling to room temperature, centrifuge to separate the supernatant, and then ultrasonically assist extraction ...

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PUM

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Abstract

The invention discloses antitumor oral liquid and a preparation method thereof. The antitumor oral liquid is mainly prepared from the following raw materials in parts by weight: 50-200 parts of ixeris chinensis nakai, 8-12 parts of rhizoma smilacis glabrae, 2-5 parts of pseudobulbus cremastrae seu pleiones, 5-8 parts of semen oroxyli bark, 10-15 parts of honeysuckle, 10-15 parts of dandelion, 8-10 parts of houttuynia cordata,5-8 parts of rhodiola rosea, 2-4 parts of frankincense, 2-4 parts of myrrh, 2-4 parts of fructus leonuri, 8-12 parts of rhizoma drynariae, 2-4 parts of kelp, 2-4 parts of seaweed, 8-12 parts of concha arcae, 4-6 parts of fried semen lepidii, 18-22 parts of radix astragali fried with honey, 8-12 parts of radix pseudostellariae, 8-12 parts of white hyacinth bean, 8-12 parts of trogopterus dung, 1-3 parts of cordyceps sinensis and 5-8 parts of fructus psoraleae. The preparation method comprises the following steps: drying and grinding the raw materials, so that raw material powder is obtained; mixing and extracting the raw material powder with ethanol with volume being 10-40 times the total volume of the raw material powder and with concentration being 60-80%, so that an extracting solution is obtained; and concentrating the extracting solution, so that a thick paste is obtained, diluting the thick paste in 1-10 times of water, sub-packaging and sealing, so that the antitumor oral liquid is obtained.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to an anti-tumor oral liquid and a preparation method thereof. Background technique [0002] Tumor refers to the new organism formed by the proliferation of local tissue cells under the action of various tumorigenic factors. According to the cell characteristics of new organisms and the degree of harm to the body, tumors are divided into two categories: benign tumors and malignant tumors, and cancer is the general term for malignant tumors. [0003] At present, chemotherapy, radiotherapy and exosomal therapy are generally used as treatment methods for malignant tumors. Radiation therapy has large side effects and damages normal cells and cancer cells at the same time. Chemotherapy generally uses antibiotics, metabolic and hormonal drugs, etc. Great side effects. Therefore, an antitumor treatment method with high safety and few side effects is desired. [0004] Traditio...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K9/08A61P35/00A61K35/618A61K35/24
CPCA61K9/0053A61K9/08A61K35/24A61K35/618A61K36/02A61K36/03A61K36/068A61K36/126A61K36/185A61K36/28A61K36/288A61K36/31A61K36/324A61K36/328A61K36/355A61K36/36A61K36/41A61K36/48A61K36/481A61K36/487A61K36/533A61K36/78A61K36/896A61K36/898A61K36/90A61K47/46A61K2236/333A61K2236/51A61K2300/00
Inventor 刘红梅刘恺李军李晓幸霍莉
Owner HEBEI UNIVERSITY
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