Pharmaceutical composition for treating scapulohumeral periarthritis and preparation method thereof

A composition and a technology for frozen shoulder, which are applied in the field of pharmaceutical compositions for the treatment of frozen shoulder and the preparation field thereof, can solve the problems of prolonged unhealing, repeated attacks, prolongation of the course of disease, etc. Zhou Yan's effect

Inactive Publication Date: 2016-06-22
王甲林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effect of physical and massage therapy is poor, recurrent attacks, long-term unhealed, and prolonged course of disease have brought great economic burden and mental pain to patients

Method used

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  • Pharmaceutical composition for treating scapulohumeral periarthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Ingredients: 15 parts of dried ginger, 2 parts of fritillary leaf, 5 parts of belladonna, 3 parts of corn silk, 2 parts of desmodium, 4 parts of barley, 3 parts of Western dandelion, 1 part of gooseberry, 0.3 parts of cicada slough, 3 servings of Artemisia argyi leaves.

[0023] Follow the extraction method below to extract:

[0024] 1) Extraction process: Take the above active ingredients according to the weight ratio, add water to immerse, heat up to 35-45°C, stir and extract for 2-3 hours, and then filter to obtain a filtrate; filter out the medicinal residues, and place the medicinal residues in 50% V ethanol In the aqueous solution, extract by ultrasonic reflux for 8-12 hours, and then filter to obtain the second filtrate; continue to add water to the medicinal residue and use steam distillation to extract the active components in the medicinal liquid to obtain the third filtrate;

[0025] 2) Combine the three filtrates, concentrate in vacuo at 45-50°C, stop conce...

Embodiment 2

[0027] Ingredients: 20 parts of dried ginger, 3 parts of fritillary leaf, 7 parts of belladonna, 5 parts of corn silk, 3 parts of desmodium, 7 parts of barley, 5 parts of Western dandelion, 2 parts of gooseberry, 0.5 part of cicada slough, 4 servings of Artemisia argyi leaves.

[0028] Extract according to the extraction method of embodiment 1, difference is that batching composition is different.

Embodiment 3

[0030] Ingredients: 18 parts of dried ginger, 3 parts of fritillary leaf, 6 parts of belladonna, 4 parts of corn silk, 2 parts of desmodium, 7 parts of barley, 4 parts of Western dandelion, 1 part of gooseberry, 0.3 parts of cicada slough, 3 parts mugwort leaves.

[0031] The extraction method is the same as in Example 1.

[0032] The active ingredients extracted in Examples 1-3 are processed into pills, granules or powders according to conventional preparation methods.

[0033] Clinical effect evaluation:

[0034] 1) Patient conditions: 200 patients with cervical spondylosis, 120 females (40-60 years old), 80 males (45-65 years old), the course of disease is 1-36 months; patients have different degrees of shoulder pain;

[0035] 2) Placebo: Lactose prepared with the same appearance, size, color, dosage form, weight, and taste as the drug prepared in the examples was prepared as a placebo for comparison;

[0036] 3) Test plan: a double-blind method is adopted for comparison...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating scapulohumeral periarthritis. The pharmaceutical composition is prepared from, by weight, 15-20 parts of dried ginger, 2-3 parts of fritillaria cirrhosa, 5-7 parts of belladonna herb, 3-5 parts of corn stigma, 2-3 parts of herbal lysimachiae, 4-7 parts of seeds of Job's tears, 3-5 parts of taraxacum officinale, 1-2 parts of myosoton aquaticum moench, 0.3-0.5 part of periostracum cicada and 3-4 parts of folium artemisiae argyi. The pharmaceutical composition has the effects of dispelling wind, eliminating dampness and clearing away heat and toxic materials, can effectively treat pain caused by scapulohumeral periarthritis and remove shoulder joint activity limitation, muscle spasm and atrophy and other symptoms, and achieves the purpose of effectively treating scapulohumeral periarthritis, and the improvement rate is 98%.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating frozen shoulder and a preparation method thereof. Background technique [0002] Frozen shoulder is a pain that gradually occurs in the shoulder, especially at night, gradually aggravating, and the function of the shoulder joint is limited and aggravated day by day. After reaching a certain level, it is gradually relieved, and finally the shoulder joint capsule and its surroundings are completely restored. Chronic idiosyncratic inflammation of ligaments, tendons and bursae. Scapulohumeral periarthritis is the common disease that is cardinal symptom with shoulder arthralgia and inconvenient activity. The age of primary disease is about 50 years old, and the incidence rate of women is slightly higher than that of men, and it is more common in manual laborers. If it is not treated effectively, it may seriou...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P19/02A61P29/00A61K35/64
CPCA61K36/9068A61K35/63A61K36/185A61K36/282A61K36/288A61K36/36A61K36/81A61K36/8966A61K36/899A61K36/8994A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 不公告发明人
Owner 王甲林
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