A kind of palbociclib pharmaceutical composition and preparation method thereof

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, antineoplastic drugs, etc., can solve the problems of low yield, difficult to clean, expensive equipment, etc.
CN105748435BActive Publication Date: 2019-03-29河北泽运生物医药科技有限公司
3 Cites 3 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
河北泽运生物医药科技有限公司
Publication Date
2019-03-29

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a palbociclib pharmaceutical composition, comprising palbociclib or its medicinal salt and a pharmaceutically acceptable auxiliary material, wherein the palbociclib or its medicinal salt is 50-150 Mum, and the medicinal salt includes isethionates, hydrochlorides, sulfates or benzene sulfonates.Direct mixing and capsuling process of raw and auxiliary materials is used for the pharmaceutical composition provided herein, the biological availability is high, product quality stability is good, the technical process is easy to control, inter-batch reproducibility is good, and the composition is easy to industrialize.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the technical field of pharmaceutical preparations, and relates to a pharmaceutical composition of palbociclib, in particular to a pharmaceutical composition of palbociclib prepared by a direct mixing process and a preparation method thereof. Background technique

[0002] Breast cancer is one of the most common malignant tumors in women. The incidence rate accounts for 7% to 10% of all kinds of malignant tumors in the whole body. It is second only to uterine cancer and has become the main cause of threat to women's health. Its incidence is often related to heredity, and the incidence rate is higher in women around the age of 40 to 60 before and after menopause. It is one of the malignant tumors that usually occurs in the glandular epithelial tissue of the breast, seriously affecting the physical and mental health of women and even threatening their lives. The incidence rate has been higher than the world average.

[0003] Aro...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More