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Traditional Chinese medicinal composition for treating primary biliary cirrhosis and preparation method thereof

A technology of biliary cirrhosis and composition, which is applied in the field of traditional Chinese medicine composition for treating primary biliary cirrhosis and its preparation, which can solve the problems of toxic and side effects, poor curative effect, easy repetition, etc., and achieve small side effects and low cost , no repeated effect

Inactive Publication Date: 2016-10-12
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In view of the above situation, in order to overcome the defects of the prior art, the object of the present invention is to provide a traditional Chinese medicine composition for the treatment of primary biliary cirrhosis and a preparation method thereof, which can effectively solve the problems of poor curative effect, instability, toxic side effects, and easy repeated treatment. The problem

Method used

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  • Traditional Chinese medicinal composition for treating primary biliary cirrhosis and preparation method thereof
  • Traditional Chinese medicinal composition for treating primary biliary cirrhosis and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The present invention is calculated by the following parts by weight: Bupleurum 800-1500 parts, Smilax 400-600 parts, cat's claw 800-1500 parts, madder 1500-2000 parts, leech 400-500 parts, earthworm 800-1000 parts, 1,000-1,500 parts of licorice as raw materials, or 8-15g of bupleurum, 4-8g of smilax, 8-15g of cat's claw, 15-20g of madder, 4-5g of leeches, and 8-10g of earthworm by weight , Radix Glycyrrhizae 10-15g is made as raw material, and preparation method is:

[0013] 1) Mix the above raw materials, add water and decoct twice, add 6-10 times the weight of the raw materials each time, decoct for 1-2 hours each time, combine the two decoctions, filter, and concentrate the filtrate to 70 ° C. Clear paste with a relative density of 1.05-1.10, let it cool;

[0014] 2) Add ethanol to make the clear paste have an alcohol content of 70%, stir, let it stand for 24 hours, filter off the precipitate, recycle the ethanol from the filtrate and concentrate it into a clear pa...

Embodiment 2

[0018] The present invention is made from the following parts by weight: 1500 parts of Bupleurum, 500 parts of Smilax, 1500 parts of Cat's Claw, 1500 parts of Rubia, 500 parts of Leeches, 1000 parts of Earthworm and 1500 parts of Licorice, or by the following weight 15g of bupleurum, 5g of sarsaparilla, 15g of cat's claw, 15g of madder, 5g of leech, 10g of earthworm and 15g of licorice are used as raw materials. The preparation method is:

[0019] 1) Mix the above raw materials, add water and decoct twice, each time add 6 times the weight of the raw materials and decoct for 1 hour each time, combine the two decoctions, filter, and concentrate the filtrate to 70 ° C to measure the relative density of 1.05 clear ointment, let cool;

[0020] 2) Add ethanol so that the alcohol content of the clear paste is 70%, stir, let it stand for 24 hours, filter off the precipitate, recycle the ethanol from the filtrate and concentrate it into a clear paste with a relative density of 1.10 mea...

Embodiment 3

[0024] The present invention is made from the following parts by weight: 500 parts of Bupleuri, 400 parts of Smilax, 700 parts of cat's claw, 1200 parts of madder, 300 parts of leech, 500 parts of earthworm and 500 parts of licorice as raw materials, or by the following weight 5g of Bupleurum bupleuri, 4g of sarsaparilla, 7g of cat's claw, 12g of madder, 3g of leech, 5g of earthworm and 5g of licorice are used as raw materials. The preparation method is:

[0025] 1) Mix the above raw materials, add water and decoct twice, each time add 8 times the weight of the raw materials and decoct for 2 hours each time, combine the two decoctions, filter, and concentrate the filtrate to 70 ° C to measure the relative density of 1.10 clear ointment, let cool;

[0026] 2) Add ethanol so that the alcohol content of the clear ointment is 70%, stir, let it stand for 24 hours, filter off the precipitate, recycle the ethanol from the filtrate and concentrate it into a clear ointment with a relat...

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Abstract

The invention relates to a traditional Chinese medicinal composition for treating primary biliary cirrhosis and a preparation method thereof. The traditional Chinese medicinal composition can be used for effectively solving the problems of poor and unstable curative effect, toxic and side effects and easy recurrence and is prepared from the following raw materials in parts by weight: 500-1500 parts of bupleurum, 300-800 parts of chinaroot greenbrier, 500-1500 parts of radix ranunculi ternati, 1000-2000 parts of madder, 300-500 parts of leech, 500-1000 parts of earthworm and 500-1500 parts of liquorice. The traditional Chinese medicinal composition provided by the invention has the main effects of clearing away heat and toxic materials, soothing the liver and gallbladder and promoting blood circulation to remove blood stasis, is good at treating the primary biliary cirrhosis with liver and gallbladder stasis, dampness-heat stay inside and qi stagnation and blood stasis syndromes, adopts liver and gallbladder soothing, blood circulation promoting and blood stasis removing as main therapies, integrates pharmaceutical effects of soothing gallbladder, promoting menstruational flow and regulating flow of qi and combined action of main and collateral channels into a whole and has high significant efficiency and effective rate, stable curative effect, no recurrence, small side effect and low cost.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating primary biliary cirrhosis and a preparation method thereof. Background technique [0002] Primary biliary cirrhosis (PBC) is a chronic intrahepatic cholestatic disease. Its pathogenesis is not completely clear, and it may be related to abnormal autoimmunity caused by factors such as genetic background, infection and environment. PBC is more common in middle-aged and elderly women, and the most common clinical manifestations are fatigue and pruritus; its pathological features are progressive, non-suppurative, and destructive intrahepatic cholangitis, which can eventually develop into cirrhosis. The positive serum anti-mitochondrial antibody (AMA), especially the positive AMA-2 subtype, has a high sensitivity and specificity for the diagnosis of this disease. At present, ursodeoxycholic acid (UDCA) is still the o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/90A61P1/16A61K35/62
Inventor 刘光伟吕秋霞曹玉净桂松林
Owner HENAN UNIV OF CHINESE MEDICINE
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