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Moisturizing hyaluronic acid composition and preparation method and application thereof

A technology of hyaluronic acid and hyaluronidase, which is applied in pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., to achieve the effect of improving silkiness and reducing stickiness

Active Publication Date: 2016-11-16
BLOOMAGE BIOTECHNOLOGY CORP LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0011] In order to solve the above problems in the research of hyaluronic acid in the prior art, the inventor provides a hyaluronic acid moisturizing composition

Method used

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  • Moisturizing hyaluronic acid composition and preparation method and application thereof
  • Moisturizing hyaluronic acid composition and preparation method and application thereof
  • Moisturizing hyaluronic acid composition and preparation method and application thereof

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preparation example Construction

[0041] Preparation of each combination sample: according to the molecular weight combination in the table, and weigh them respectively according to the ratio of 6:2:2, put the 3 molecular weight sodium hyaluronate of each combination into a mortar and grind them thoroughly to make them fully mixed. After homogenization, each combined sample was obtained.

[0042] Use the basic moisturizer formula (glycerin 2%, butylene glycol 2%, water), respectively add the samples of Combination 1 to Combination 5, stir to dissolve (the concentration of each combination sample in the solution is 0.5%), without transparent A sample of sodium hyaluronate served as a control. Test the moisture content of the skin after applying different samples, so as to screen the molecular weight combination with better moisturizing effect.

[0043] 2. Skin moisture test method

[0044] The age of the subjects ranged from 22 to 55 years old, a total of 6 people. Mark 4×4cm on the inner forearm of the left...

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Abstract

The invention relates to the technical field of hyaluronic acid, in particular to a moisturizing hyaluronic acid composition. The moisturizing hyaluronic acid composition comprises the following components in percentage by weight: 60-62% of hyaluronic acid with the molecular weight of 1100kDa or salt thereof, 18-20% of hyaluronic acid with the molecular weight of 400kDa or salt thereof and 18-20% of hyaluronic acid with the molecular weight of 6kDa or salt thereof. The moisturizing hyaluronic acid composition is applied to skin-cleaning, skin-caring and cosmetic products. Through reasonable combination of high-molecular weight, low-molecular weight and micro-molecular weight hyaluronic acids, the moisturizing hyaluronic acid composition has an all-layer three-dimensional moisturizing effect on the skin on a dermal layer, an epidermal layer, a corneum and the skin surface; the moisturizing hyaluronic acid composition is endowed with an instant and long-lasting moisturizing effect; in an aspect of skin touch, the sticky feeling of the high-molecular weight hyaluronic acid is significantly reduced and the silky feeling of the low-molecular weight hyaluronic acid is improved; the moisturizing hyaluronic acid composition can be applied to all types of cosmetics and cleaning products.

Description

technical field [0001] The invention relates to the technical field of hyaluronic acid, in particular to a hyaluronic acid moisturizing composition, and also relates to a preparation method and application of the hyaluronic acid moisturizing composition. Background technique [0002] Hyaluronic acid, also known as hyaluronic acid, is an acidic mucopolysaccharide with excellent lubricity and moisturizing properties. It is known as a natural moisturizing factor. It has been widely used in cosmetics and is also sought after by consumers. The molecular weight distribution of hyaluronic acid is very wide, and different molecular weights have different physical, chemical and biological properties. High-molecular-weight hyaluronic acid has excellent properties of water retention, moisturizing, film-forming, and lubrication; medium-low molecular weight hyaluronic acid can hydrate and soften the stratum corneum, promote skin nutrition supply and waste excretion, and soften the skin. ...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61Q19/00A61Q19/08
CPCA61K8/735A61K2800/5922A61Q1/02A61Q19/00A61Q19/08A61Q19/10
Inventor 黄思玲孙建斐王海英耿凤郭学平
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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