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Infusion injection, and preparation method and application thereof

A technology for infusion needles and injections, which is used in pharmaceutical formulations, drug delivery, and medical preparations containing active ingredients, etc., can solve problems such as decreased immunity, accelerated death of cancer patients, and unfavorable cancer treatment. The effect of improving human immunity

Pending Publication Date: 2017-05-31
承德雾灵生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] To sum up, since cancer is a genetic disease, only by reversing abnormal genes into normal genes can cancer be cured fundamentally. Traditional cancer treatment methods, such as surgery, radiotherapy and chemotherapy, to some extent , in the process of treatment, it usually kills some normal cells of the human body while killing cancer cells. The metastatic spread of cancer patients will accelerate the death of cancer patients

Method used

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  • Infusion injection, and preparation method and application thereof
  • Infusion injection, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] An infusion injection, consisting of the following active ingredients in parts by weight: 78 parts of 2,4,6-trinitro-5-tert-butyl-m-xylene oil, 10 parts of red ginseng, 2 parts of Radix Ophiopogon japonicus and 10 parts of Radix Astragali .

[0075] The preparation method of described infusion injection, comprises the following steps:

[0076] (1) Dissolve 2,4,6-trinitro-5-tert-butyl m-xylene oil in 6% aqueous sodium bicarbonate solution, heat to 88°C, dissolve for 40 minutes, the mass volume of the two The ratio is 1:13, then carry out normal pressure filtration, then carry out high pressure filtration under the pressure of 1.5MPa, obtain the sodium bicarbonate aqueous solution containing 2,4,6-trinitro-5-tert-butyl m-xylene oil A;

[0077] (2) Grind and mix red ginseng, Ophiopogon japonicus and Astragalus membranaceus, add water to the mixture of red ginseng, Ophiopogon japonicus and Astragalus membranaceus at a mass-to-volume ratio of 1:18, decoct at 95°C for 40 mi...

Embodiment 2

[0080] An infusion injection, consisting of the following active ingredients in parts by weight: 75 parts of 2,4,6-trinitro-5-tert-butyl-m-xylene oily body, 13 parts of red ginseng, 1 part of Radix Ophiopogon japonicus and 11 parts of Radix Astragali .

[0081] The preparation method of described infusion injection, comprises the following steps:

[0082] (1) Dissolve 2,4,6-trinitro-5-tert-butyl m-xylene oil in 5% aqueous sodium bicarbonate solution, heat to 82°C, dissolve for 38 minutes, the mass volume of the two The ratio is 1:15, then normal pressure filtration is carried out, and then high pressure filtration is carried out under a pressure of 1.2MPa to obtain an aqueous solution of sodium bicarbonate containing 2,4,6-trinitro-5-tert-butyl-m-xylene oil A;

[0083] (2) Grind and mix red ginseng, radix radix and astragalus, add water to the mixture of red ginseng, radix radix and astragalus at a mass-to-volume ratio of 1:15, decoct at 90°C for 39 minutes and filter the re...

Embodiment 3

[0086] An infusion injection, consisting of the following active ingredients in parts by weight: 79 parts of 2,4,6-trinitro-5-tert-butyl-m-xylene oily body, 8 parts of red ginseng, 2 parts of Radix Ophiopogon japonicus and 11 parts of Radix Astragali .

[0087] The preparation method of described infusion injection, comprises the following steps:

[0088] (1) Dissolve 2,4,6-trinitro-5-tert-butyl m-xylene oil in 6% aqueous sodium bicarbonate solution, heat to 85°C, dissolve for 35 minutes, the mass volume of the two The ratio is 1:12, then normal pressure filtration is carried out, and then high pressure filtration is carried out under a pressure of 1.2MPa to obtain an aqueous solution of sodium bicarbonate containing 2,4,6-trinitro-5-tert-butyl m-xylene oil A;

[0089] (2) Grind and mix red ginseng, Ophiopogon japonicus and Astragalus membranaceus, add water to the mixture of red ginseng, Ophiopogon japonicus and Astragalus membranaceus at a mass-to-volume ratio of 1:13, dec...

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Abstract

The invention relates to an infusion injection, and a preparation method and application thereof. The infusion injection contains the following active components in parts by weight: 75-90 parts of 2,4,6-trinitro-tert-butyl-m-xylene grease, 8-15 parts of red ginseng, 1-3 parts of radix ophiopogonis and 8-15 parts of radix astragali. A 5-7% sodium bicarbonate water solution is utilized to dissolve the active components, and filtration is carried out to obtain the infusion injection capable of cancer cell oriented killing. The infusion injection can obviously enhance the autoimmunity of the human body, has wide adaptability for various cancer cells, is especially suitable for treating prostatic cancer, rectum cancer, bladder cancer, mammary cancer, esophagus cancer, encephaloma, liver cancer and osteocarcinoma, has no toxic or side effect, greatly enhances the cure rate of cancerous persons, and has the effect of preventing cancers.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to an infusion injection and a preparation method and application thereof. Background technique [0002] Cancer is the number one killer of human life. The report of the World Health Organization shows that in 2008, there were about 12.7 million new cancer patients and 7.6 million deaths from cancer in the world. Especially in developing countries, the number of new cancer cases reached 56%. The World Health Organization predicts that by 2020, the global cancer incidence rate will increase by 50%, that is, 15 million new cancer patients will be added every year, and the number of cancer patients worldwide will reach 30 million. On April 13, 2015, the National Cancer Registry Center announced that there would be one new cancer in less than 10 seconds in China, with 3.37 million new cancers and 2.11 million deaths throughout the year. The World Health Organization predicts that by 2030 the wor...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K36/8968A61P37/04A61P35/00A61K31/04
CPCA61K36/258A61K9/0019A61K9/08A61K31/04A61K36/481A61K36/8968A61K47/02A61K2300/00
Inventor 栾世勋栾海燕
Owner 承德雾灵生物医药科技有限公司
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