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A kind of anti-tumor traditional Chinese medicine composition with synergistic and attenuating effects of chemotherapy and its application

A technology of attenuating effect and composition, applied in the field of medicine, can solve problems such as toxic and side effects, necrosis, etc., and achieve the effects of reducing toxic and side effects, high safety, and improving anti-tumor effect

Active Publication Date: 2020-08-18
北京济生康诺网络科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, human beings have not yet conquered cancer, but with the development of advanced medical technology, some treatment methods and methods have a certain effect. Modern medicine mainly treats tumors with chemotherapy, radiotherapy and surgery, but a large number of clinical treatments have proved that chemotherapy and radiotherapy At the same time, it is also accompanied by different degrees of toxic and side effects. While killing the tumor, it will also kill the normal cells of the human body to a large extent, causing vomiting, fatigue, diarrhea, leukopenia, tissue edema, nerve paralysis, and tissue damage to the human body. Necrosis etc.

Method used

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  • A kind of anti-tumor traditional Chinese medicine composition with synergistic and attenuating effects of chemotherapy and its application
  • A kind of anti-tumor traditional Chinese medicine composition with synergistic and attenuating effects of chemotherapy and its application
  • A kind of anti-tumor traditional Chinese medicine composition with synergistic and attenuating effects of chemotherapy and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 (capsule)

[0027] Take 100g of turmeric, 60g of astragalus, 20g of pepper, and 20g of tea leaves. After pulverizing the above-mentioned raw materials, use 10-30 times the dry weight of the raw materials to heat and reflux to extract twice for 1 hour each time. Combine the extracts, filter, and concentrate under reduced pressure. Obtain an extract; add adhesives, fillers, etc. to the extract, granulate and dry, sieve and fill into capsules.

Embodiment 2

[0028] Embodiment 2 (capsules)

[0029] Take 80g of turmeric, 40g of astragalus, 40g of pepper, and 40g of tea leaves. After pulverizing the above raw materials, heat and reflux extraction with pure water 10-30 times the dry weight of raw materials for 2 times, each time for 1h. Combine the extracts, filter, and concentrate under reduced pressure. Obtain an extract; add adhesives, fillers, etc. to the extract, granulate and dry, sieve and fill into capsules.

Embodiment 3

[0030] Embodiment 3 (capsules)

[0031] Take 140g of turmeric, 20g of astragalus, 30g of pepper, and 10g of tea leaves. After pulverizing the above raw materials, heat and reflux extraction with pure water 10-30 times the dry weight of raw materials for 2 times, each time for 1h. Combine the extracts, filter, and concentrate under reduced pressure. Obtain an extract; add adhesives, fillers, etc. to the extract, granulate and dry, sieve and fill into capsules.

[0032] The following experiments are used to further illustrate the synergistic and attenuating effects of the traditional Chinese medicine composition of the present invention in the antitumor effect alone and in combination with chemotherapeutic drugs.

[0033] 1. The effect of traditional Chinese medicine composition on the growth of transplanted tumor in mice

[0034] 1. Experimental method

[0035] Mice with transplanted Lewis lung cancer, mice with transplanted S180 tumor and mice with transplanted H22 liver can...

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Abstract

The invention relates to a chemotherapy combined anti-tumor traditional Chinese medicine composition with effect-enhancing and toxicity-reducing effects and application of the chemotherapy combined anti-tumor traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30 to 70 parts of turmeric, 10 to 50 parts of astragalus membranaceus, 5 to 20 parts of pepper and 5 to 20 parts of tea leaves. The traditional Chinese medicine composition disclosed by the invention is good in anti-tumor effect; when the traditional Chinese medicine composition is combined with a chemotherapy medicine for treatment of tumors, the anti-tumor effect is greatly enhanced, namely the anti-tumor effect achieved by the combination of the traditional Chinese medicine composition and the chemotherapy medicine is more obvious than that of independent use of the traditional Chinese medicine composition or the chemotherapy medicine; meanwhile, the combination of the traditional Chinese medicine composition and the chemotherapy medicine can reduce the toxic and side effects of the chemotherapy medicine.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an anti-tumor traditional Chinese medicine composition with synergistic and attenuating effects of chemotherapy and its application. Background technique [0002] Cancer, also known as malignant tumor, is a kind of disease characterized by malignant proliferation of cells. With the changes of human living environment, lifestyle and social age composition, the incidence and mortality of cancer have continued to rise in recent years. According to the 2012 China Cancer Registration Annual Report, there are 3.12 million new cancer cases in the country every year, and more than 2.5 million people die from cancer every year. The World Health Organization predicts that by 2020, the number of new cancer diseases will exceed 15 million people every year. Cancer has become the number one killer of human beings in the new century and has become the largest public health problem...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P35/00A61P35/02A61K9/48
CPCA61K9/4841A61K36/481A61K36/67A61K36/82A61K36/9066A61K2300/00
Inventor 马松江任鲁华张莎
Owner 北京济生康诺网络科技有限公司
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