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Anti-adhesion hygroscopic medical acid-sensitive antiseptic gauze and preparation method thereof

An anti-adhesion and acid-sensitive technology, which is applied in the direction of absorbent pads, medical science, bandages, etc., can solve the problems of affecting wound healing, increasing toxic side effects, secondary damage of wounds, etc., to achieve the inhibition of bacterial resistance, easy industrial production, The effect of simple preparation method

Active Publication Date: 2017-09-01
WUHAN TEXTILE UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the course of clinical use, there are many technical problems in medical gauze, which are mainly reflected in the following aspects: 1. The gauze has poor hygroscopicity and cannot effectively absorb wound exudate, causing the exudate to solidify at the wound, affecting the healing of the wound 2. The anti-adhesion effect of gauze is relatively poor, so that new granulation tissue is easy to grow into the mesh of gauze, which will not only cause secondary damage to the wound surface when changing gauze, but also be unfavorable for wound healing and bring greater misery to the patient 3. The release behavior of antibacterial agents loaded on gauze is not responsive to the bacterial growth environment, resulting in excessive use of antibiotics, increasing toxic side effects and aggravating the emergence of bacterial drug resistance. At the same time, studies have shown that the microenvironment of bacterial growth,

Method used

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  • Anti-adhesion hygroscopic medical acid-sensitive antiseptic gauze and preparation method thereof
  • Anti-adhesion hygroscopic medical acid-sensitive antiseptic gauze and preparation method thereof
  • Anti-adhesion hygroscopic medical acid-sensitive antiseptic gauze and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Mix Daqingye and Houttuynia cordata with a mass ratio of 1:1, add 4 times the mass of water, heat to boiling and continue to decoct for 1 hour to obtain a decoction containing filtrate and filter residue, filter to obtain the filtrate, and then Concentrate the filtrate under low temperature and reduced pressure to a quarter of the volume of the original filtrate to prepare the Chinese medicine extract and keep it for later use; weigh the Chinese medicine extract and sodium alginate with a mass ratio of 80:2:2.5:5:100 , citric acid, glycerin and water, wherein, the specific operation process is that citric acid, glycerin and Chinese medicine extract are dissolved in water (preferred ultrapure water in this embodiment), fully stirred to obtain a homogeneous mixture, and then rapidly stirred Add sodium alginate to the mixture under certain conditions, and stir evenly to obtain a colloidal mixed soaking solution with a certain viscosity;

[0035] Take a piece of ordinary me...

Embodiment 2

[0037] Mix Daqingye and Houttuynia cordata with a mass ratio of 1:2, add 4 times the mass of water, heat to boiling and continue to decoct for 1 hour to obtain a decoction containing filtrate and filter residue, filter to obtain the filtrate, and then Concentrate the filtrate under low temperature and reduced pressure to a quarter of the volume of the original filtrate to prepare the Chinese medicine extract and keep it for later use; weigh the Chinese medicine extract and sodium alginate with a mass ratio of 80:3.5:4:9:180 , citric acid, glycerin and water, wherein, the specific operation process is that citric acid, glycerin and Chinese medicine extract are dissolved in water (preferred ultrapure water in this embodiment), fully stirred to obtain a homogeneous mixture, and then rapidly stirred Add sodium alginate to the mixture under certain conditions, and stir evenly to obtain a colloidal mixed soaking solution with a certain viscosity;

[0038] Take a piece of ordinary me...

Embodiment 3

[0040]Mix Daqingye and Houttuynia cordata with a mass ratio of 1:1, add 4 times the mass of water, heat to boiling and continue to decoct for 1 hour to obtain a decoction containing filtrate and filter residue, filter to obtain the filtrate, and then Concentrate the filtrate under low temperature and reduced pressure to a quarter of the volume of the original filtrate to prepare the Chinese medicine extract and keep it for later use; weigh the Chinese medicine extract and sodium alginate with a mass ratio of 130:2:2.5:5:100 , citric acid, glycerol and water, wherein the specific operation process is to dissolve citric acid, glycerin and traditional Chinese medicine extract into water, stir well to obtain a uniform mixture, and then add sodium alginate to the mixture under rapid stirring conditions , and stir evenly to obtain a colloidal mixed soaking solution with a certain viscosity;

[0041] Take a piece of ordinary medical gauze, after the medical gauze has been fully activ...

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Abstract

The invention discloses a piece of anti-adhesion hygroscopic medical acid-sensitive antiseptic gauze and a preparation method thereof, and belongs to the fields of medical gauze and a preparation method thereof. The piece of gauze comprises a medical gauze base material and a gel layer adhered onto the medical gauze base material, wherein the gel layer is prepared from a mixed soaking solution; the mixed soaking solution comprises an antibacterial traditional Chinese medicine extract, sodium alga acid, citric acid, glycerin and water; the antibacterial traditional Chinese medicine extract is a complex extract of folium isatidis and herba houttuyniae. The preparation method comprises the following steps: boiling, filtering and concentrating to obtain the antibacterial traditional Chinese medicine extract; mixing the antibacterial traditional Chinese medicine extract, citric acid, glycerin and sodium alga acid solution to obtain a mixed solution; immersing ordinary medical gauze in the mixed solution, fully wetting the medical gauze, taking out the medical gauze, and drying the medical gauze in a drying oven. The preparation method is simple, and the prepared medical gauze has an anti-adhesion hygroscopic effect, is acid-sensitive and has an antibacterial effect.

Description

technical field [0001] The invention relates to the field of medical gauze and a preparation method thereof, in particular to an anti-adhesion hygroscopic medical acid-sensitive antibacterial gauze and a preparation method thereof. Background technique [0002] Medical gauze is mainly used to bandage wounds in the field of health care to protect and protect wounds. However, in the course of clinical use, there are many technical problems in medical gauze, which are mainly reflected in the following aspects: 1. The gauze has poor hygroscopicity and cannot effectively absorb wound exudate, causing the exudate to solidify at the wound, affecting the healing of the wound 2. The anti-adhesion effect of gauze is relatively poor, so that new granulation tissue is easy to grow into the mesh of gauze, which will not only cause secondary damage to the wound surface when changing gauze, but also be unfavorable for wound healing and bring greater misery to the patient 3. The release be...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/20A61L15/40A61L15/46A61L15/44
CPCA61L15/20A61L15/28A61L15/40A61L15/44A61L15/46A61L2300/30A61L2300/404A61L2300/45C08L5/04
Inventor 王栋鲁振坦张佳琪刘琼珍刘轲王跃丹蒋海青
Owner WUHAN TEXTILE UNIV
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