Infantile autism biological marker and detection kit thereof
A technology of biomarkers and detection reagents, applied in the field of biomedicine, can solve the problems of low diagnostic accuracy, lack of blood diagnostic methods and effective treatment plans, etc.
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[0077] In this embodiment, ELISA is used to detect and analyze the stool samples of healthy people and patients with autism, and then perform statistical tests to determine the biomarkers related to the group of patients with autism. Specific steps are as follows:
[0078] 1. Sample source
[0079] Autism group: children with ASD from the Department of Psychology and Speech Therapy, Shenzhen Children's Hospital, collected from July to December 2015. Inclusion criteria: ①According to the latest international diagnostic criteria, that is, "Diagnostic and Statistical Manual of Mental Disorders, 5th Edition, DSM-5", diagnosed as ASD "requiring a lot of support" Children; ②age <14 years old; ③gender is not limited. Exclusion criteria: ① suffering from other mental diseases (such as schizophrenia, etc.); ② suffering from other neurodevelopmental disorders; ③ suffering from genetic metabolic diseases; ④ suffering from severe neurological diseases and history of craniocerebral injur...
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