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3D printing method

A 3D printer and 3D technology, applied in the field of 3D printing, can solve problems such as cytotoxic biological rejection, and achieve the effect of easy low temperature preservation, easy preservation, and guarantee of biological activity.

Active Publication Date: 2017-10-20
PARTICLE CLOUD BIOTECHNOLOGY (HANGZHOU) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, hydrogel is used as a support material for 3D printing, and there are technical problems of cytotoxicity and bio-rejection

Method used

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Examples

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Embodiment 1

[0023] figure 1 Shown is a flow chart of a 3D printing method provided by the embodiment of the present application, the method is applied to print a 3D model through a 3D printer, and the method includes:

[0024] Step 1: making the temperature of the freezing bed reach a predetermined temperature;

[0025] Specifically, the frozen bed is a tray on which the printed model is placed during 3D printing, and a cooling element can be arranged at the bottom of the frozen bed, and the cooling element can provide cooling energy to the frozen bed, so that the The freezing bed maintains a predetermined temperature. After the temperature of the freezing bed reaches the predetermined temperature, through the cooperation of the cooling element and the freezing bed, the freezing bed is in a constant state of predetermined temperature during the printing process, so that the 3D printing process can be maintained at a lower temperature Under these conditions, the activity of the biologica...

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Abstract

The invention relates to the technical field of 3D printing, especially to a 3D printing method. The method comprises: step 1, allowing a refrigeration bed to reach a predetermined temperature; step 2, extruding liquid water to a predetermined position of the refrigeration bed, and during an extrusion process of liquid water, fast freezing the liquid water for solidification to form a first base support; step 3, extruding a biological material to the first base support to form a first biological material layer; step 4, extruding liquid water to the first biological material layer, and fast freezing the liquid water for solidification to form a second base support; step 5, extruding the biological material to the second base support to form a second biological material layer; and step 6, repeating the step 4 and 5 until printing of a 3D model is completed. According to the technical scheme, the technical problem of cytotoxicity and biological rejection due to a support material of 3D printing in the prior art is solved.

Description

technical field [0001] The invention relates to the technical field of 3D printing, in particular to a 3D printing method. Background technique [0002] The rapid development of 3D printing technology has brought new solutions to the field of bioengineering. Through 3D printing technology, the production and manufacture of three-dimensional multicellular architecture can be realized. In the prior art, 3D printing of biomaterials mostly uses hydrogel as the supporting material. Hydrogel is a cross-linked polymer with water as the dispersion medium. A part of hydrophobic groups and hydrophilic residues are introduced into the water-soluble polymer with network cross-linked structure, which can be swollen by water but insoluble in water. It can absorb a large amount of water and swell significantly, and can continue to maintain its original structure without being dissolved after significant swelling. [0003] At present, the theory of polymer gel is still not perfect, and th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/00B29C64/40B29C64/112B33Y30/00B33Y10/00
CPCB33Y10/00B33Y30/00C12M21/08C12M33/00
Inventor 曾庆丰张鑫段剑飙
Owner PARTICLE CLOUD BIOTECHNOLOGY (HANGZHOU) CO LTD
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