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Traditional Chinese medicinal composition for treating toxoplasmosis and preparation method thereof

A technology of toxoplasmosis and its composition, which is applied in the field of traditional Chinese medicine, can solve the problems of not being able to take it for a long time, inhibit bone marrow, and rashes, and achieve the effects of avoiding chemical residues and social pollution, with small side effects, and not easy to relapse

Inactive Publication Date: 2017-11-24
戴嵩
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, sulfadiazine, pyrimethamine, and spiramycin are the main clinical drugs for the treatment of toxoplasmosis. Long-term use, but the recurrence rate is high after drug withdrawal, and the radical cure effect is poor

Method used

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  • Traditional Chinese medicinal composition for treating toxoplasmosis and preparation method thereof
  • Traditional Chinese medicinal composition for treating toxoplasmosis and preparation method thereof
  • Traditional Chinese medicinal composition for treating toxoplasmosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Prescriptions: 10 grams of Spleen Cold Grass; 9 grams of Ningbo Dingshu; 15 grams of Herba Auricularis; 9 grams of Licorice.

[0048] Concrete preparation process is as follows:

[0049] a. Soak Spleen Cold Grass, Ningbo Dructus, Earwort, Licorice and 3 times the total weight of 4 traditional Chinese medicines in water for 24 hours, decoct 3 times, keep for 0.5 hours after each boil, combine the decoction and concentrate until thick.

[0050] b. Add 95% ethanol to the concentrated solution to adjust the alcohol concentration to 60%, fully stir and mix, precipitate, filter, and recover ethanol from the filtrate. Add ethanol to the medicinal solution after recovering ethanol to adjust the alcohol concentration to 75%, stir and precipitate for 48 hours, filter, recover the ethanol from the filtrate and concentrate until it has no alcohol smell, add 4 times the amount of water to the medicinal solution, refrigerate and precipitate for 48 hours, filter to obtain spleen The m...

Embodiment 2

[0053] Prescription: 13 grams of spleen cold grass; 12 grams of Ningbo fenshu; 18 grams of ear grass; 6 grams of licorice.

[0054] a. Soak Spleen Cold Grass, Ningbo Dructus Shu, Ear Grass, Licorice and 4 times the total weight of traditional Chinese medicines in water for 30 hours, decoct 3 times, keep for 1 hour after each boil, combine the decoctions and concentrate until thick.

[0055] b. Add 95% ethanol to the concentrated solution to adjust the alcohol concentration to 65%, stir and mix thoroughly, precipitate for 60 hours, filter, and recover ethanol from the filtrate. Add ethanol to the medicinal solution after recovering ethanol to adjust the alcohol concentration to 75%, stir and precipitate for 48 hours, filter, recover the ethanol from the filtrate and concentrate until it has no alcohol smell, add 2 times the amount of water to the medicinal solution, refrigerate and precipitate for 24 hours, filter to obtain spleen The medicinal solution made from Hancao, Ningb...

Embodiment 3

[0058] Prescriptions: 30 grams of Spleen Cold Grass; 25 grams of Ningbo Ding Shu;

[0059] a. Soak Spleen Cold Grass, Ningbo Dructus, Earwort, Licorice and 3 times the total weight of 4 traditional Chinese medicines in water, soak for 27 hours, decoct 3 times, keep for 1 hour after each boiling, combine the decoction and concentrate to Thick;

[0060] b. Add 95% ethanol to the concentrated solution to adjust the alcohol concentration to 70%, stir and mix thoroughly, precipitate for 48 hours, filter, and recover ethanol from the filtrate. Add ethanol to the medicinal solution after recovering ethanol to adjust the alcohol concentration to 80%, stir and precipitate for 48 hours, filter, recover the ethanol from the filtrate and concentrate until it has no alcohol smell, add 2 times the amount of water to the medicinal solution, refrigerate and precipitate for 48 hours, filter to obtain spleen The medicinal solution made from Hancao, Ningbo fenshu, eargrass, and licorice.

[00...

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating toxoplasmosis and a preparation method thereof. The preparation method comprises the following steps: decocting total 4 traditional Chinese medicinal materials, i.e., veronica aruensis, deutzia ningpoensis rehd, utricularia bifida and licorice root, with water for 2-3 times, mixing decoctions, and concentrating to paste; adding 95% alcohol to regulate the alcohol concentration to 60-70 percent, precipitating, filtering and concentrating the filtrate; adding 95% alcohol into the concentrated medicinal solution to regulate the alcohol concentration to be 75-80 percent, precipitating, filtering and concentrating the filtrate; and adding water, refrigerating the concentrated medicinal solution, precipitating, filtering and concentrating. The traditional Chinese medicinal composition has high cure rate for toxoplasmosis, has small side effect, is safe and convenient to use, and has small dosage and quick absorption.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and relates to a traditional Chinese medicine composition. The invention also relates to a preparation method of the traditional Chinese medicine composition and an application of the traditional Chinese medicine composition in preparing and treating toxoplasmosis. Background technique: [0002] Toxoplasma gondii is a zoonotic parasitic disease, and it is also an obligate intracellular parasitic protozoan distributed worldwide, which can parasitize humans and more than 190 kinds of animals. The world average infection rate of humans is 25% to 50%, which seriously endangers human health. Especially, Toxoplasma gondii infection during pregnancy can cause congenital abnormalities in fetuses and babies. It is one of the most important biological factors leading to intrauterine infection. Therefore, the treatment of toxoplasmosis is the focus of current experts and scholars. At p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/80A61K9/08A61P33/02
CPCA61K9/0095A61K36/185A61K36/484A61K36/53A61K36/80A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 戴嵩周广生仝娜
Owner 戴嵩
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