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Immunodetection sensor for eliminating hook effect

A technology of immunoassay and hook effect, applied in the field of immunoassay, can solve the problems of difficult sampling, heavy workload, and low specificity

Pending Publication Date: 2017-11-24
柳州康云互联科技有限公司
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  • Summary
  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Some detection items can be detected by immunoassay or biochemical detection (chemical method detection), but biochemical detection has low sensitivity, low specificity, and poor stability, so immunological detection is mainly used for detection
[0004] The current immunoassay is mainly completed by multiple dosing and testing, which requires heavy workload and difficult sampling.

Method used

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  • Immunodetection sensor for eliminating hook effect

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Embodiment Construction

[0018] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0019] Such as figure 1 As shown, an immune detection sensor that excludes the hook effect includes an immune detection area 1 and a biochemical detection judgment area 2 . When the test result of the immune detection area is negative and the test result of the biochemical detection judgment area is negative, it can be judged that the real result is negative; Hook effect, that is, false negative and true positive; when the test result in the immunological test area is positive and the test result in the biochemical test judgment area is negative, it can be judged that the real result is weakly positive, which may be in the incubation period or early onset, or may be If the diagnosis is misdiagnosed or the standard of disease has not been reached, further inspection should be carried out; when the test result of the immunological test area is p...

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PUM

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Abstract

The invention relates to an immunodetection sensor for eliminating a hook effect. The immunodetection sensor comprises an immunodetection area and a biochemical detection judgment area. When the detection result in the immunodetection area is negative and the detection result in the biochemical detection judgment area is negative, the real result can be judged to be negative; when the detection result in the immunodetection area is negative and the detection result in the biochemical detection judgment area is positive, the real result can be judged to be the hook effect, namely false negative and true positive; when the detection result in the immunodetection area is positive and the detection result in the biochemical detection judgment area is negative, the real result can be judged to be weakly positive, and further inspection is needed; and when the detection result in the immunodetection area is positive and the detection result in the biochemical detection judgment area is positive, the real result can be judged to be positive.

Description

technical field [0001] The invention relates to immune detection technology, in particular to an immune detection sensor which eliminates the hook effect. Background technique [0002] There is a hook effect in immunoassays, which refers to the phenomenon of false negatives caused by an inappropriate ratio of antigen to antibody. The excess of antibodies is called the prozone effect, and the excess of antigens is called the posterior zone effect, which seriously interferes with the judgment of the immunoassay results. The main effect is negative discrimination. [0003] Some detection items can use immunoassay or biochemical detection (chemical method detection), but biochemical detection has low sensitivity, low specificity, and poor stability, so immunological detection is mainly used. [0004] The current immunoassay is mainly completed by multiple dosing and testing, which has a heavy workload and difficult sampling. Contents of the invention [0005] The purpose of ...

Claims

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Application Information

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IPC IPC(8): G01N33/558
CPCG01N33/558
Inventor 吴凡
Owner 柳州康云互联科技有限公司
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