Immunodetection sensor for eliminating hook effect

Abstract

The invention relates to an immunodetection sensor for eliminating a hook effect. The immunodetection sensor comprises an immunodetection area and a biochemical detection judgment area. When the detection result in the immunodetection area is negative and the detection result in the biochemical detection judgment area is negative, the real result can be judged to be negative; when the detection result in the immunodetection area is negative and the detection result in the biochemical detection judgment area is positive, the real result can be judged to be the hook effect, namely false negative and true positive; when the detection result in the immunodetection area is positive and the detection result in the biochemical detection judgment area is negative, the real result can be judged to be weakly positive, and further inspection is needed; and when the detection result in the immunodetection area is positive and the detection result in the biochemical detection judgment area is positive, the real result can be judged to be positive.

Description

technical field [0001] The invention relates to immune detection technology, in particular to an immune detection sensor which eliminates the hook effect. Background technique [0002] There is a hook effect in immunoassays, which refers to the phenomenon of false negatives caused by an inappropriate ratio of antigen to antibody. The excess of antibodies is called the prozone effect, and the excess of antigens is called the posterior zone effect, which seriously interferes with the judgment of the immunoassay results. The main effect is negative discrimination. [0003] Some detection items can use immunoassay or biochemical detection (chemical method detection), but biochemical detection has low sensitivity, low specificity, and poor stability, so immunological detection is mainly used. [0004] The current immunoassay is mainly completed by multiple dosing and testing, which has a heavy workload and difficult sampling. Contents of the invention [0005] The purpose of ...

AI Technical Summary

Problems solved by technology

[0003] Some detection items can be detected by immunoassay or biochemical detection (chemical method detection), but biochemical detection has low sensitivity, low specificity, and poor stability, so immunological detection is mainly used for detection

[0004] The current immunoassay is mainly completed by multiple dosing and testing, which requires heavy workload and difficult sampling.

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