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Classification of cellular images and videos

A cell classification and image technology, applied in the field of cell image and video classification, can solve time-consuming problems

Inactive Publication Date: 2017-11-28
SIEMENS AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In conventional systems, results must be obtained through a time-consuming and computationally intensive manual testing process

Method used

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  • Classification of cellular images and videos
  • Classification of cellular images and videos
  • Classification of cellular images and videos

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Embodiment Construction

[0028] Several embodiments disclosed below relate to methods, systems, and apparatus related to a feature encoding process, referred to herein as Locality Constrained Sparse Coding (LSC) with a three-part classification pipeline. The three parts include offline unsupervised codebook learning, offline supervised classifier training, and online image and video classification. Additionally, in some embodiments, a fast approximate solution to the LSC problem is determined based on a k-Nearest Neighbor (K-NN) search and an Alternating Direction Method of Multipliers (ADMM). Various systems, methods and devices for cell sorting are described with reference to two cell imaging modalities: confocal laser endomicroscopy (CLE) and digital holographic microscopy (DHM). It should be understood, however, that the various embodiments of the present disclosure are not limited to these modalities, and may find application in a variety of clinical settings. Additionally, it should be understo...

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Abstract

A method for performing cellular classification includes extracting a plurality of local feature descriptors (220) from a set of input images (210) and applying a coding process to convert each of the plurality of local feature descriptors into a multi-dimensional code (225). A feature pooling operation (230) is applied on each of the plurality of local feature descriptors to yield a plurality of image representations and each image representation is classified as one of a plurality of cell types (240).

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Patent Application No. 62 / 126,823, filed March 2, 2015, the entire contents of which are hereby incorporated by reference. technical field [0003] The present disclosure generally relates to methods, systems and apparatus for performing classification of cellular images and videos. The proposed technique can be used, for example, to classify endoscopic images and digital holographic microscopy images. Background technique [0004] In vivo cell imaging is the study of living cells using images acquired from an imaging system such as an endoscope. Due to recent advances in fluorescent protein and synthetic fluorophore technologies, increasing research efforts are focused on in vivo cellular imaging techniques that provide insights into the fundamental nature of cell and tissue function. In vivo cell imaging techniques now span multiple modalities including, for exam...

Claims

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Application Information

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IPC IPC(8): G06K9/00G06V10/764
CPCG06V20/698G06F18/24147G06V10/764G06V20/695A61B1/000096G06F18/23213A61B90/20G02B21/0076G02B21/008
Inventor 万韶华孙善辉斯蒂芬·克卢克纳陈德仁阿里·卡门
Owner SIEMENS AG
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