Stem cell treatment matter microneedle for skin antioxidation

A technology of stem cells and processing substances, applied in the field of stem cell microneedles, can solve problems such as neglect and environmental pollution, and achieve the effects of reducing pain, low preparation cost, and avoiding waste

Inactive Publication Date: 2018-02-06
上海坤爱生物科技股份有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In the existing stem cell treatment approaches, stem cell transplantation is mainly performed through intravenous and intramuscular injections. However, in addition to injection pain, the injection process also requires professional and technical personnel to operate, and injection needles will also cause environmental pollution.
In addition, the ingredients used for treatment or beauty care in the prior art basically use stem cells obtained after cultivation or effective substances extracted from stem cells, while ignoring the secretion of secretions during the growth and reproduction of stem cells during stem cell cultivation. Curative effect, that is, the culture medium itself, its concentrate or extract can also be used for disease treatment or beauty care

Method used

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  • Stem cell treatment matter microneedle for skin antioxidation
  • Stem cell treatment matter microneedle for skin antioxidation
  • Stem cell treatment matter microneedle for skin antioxidation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1: Adipose stem cell medium has antioxidant effect when applied to cell culture

[0035] Mix the recovered adipose stem cell culture medium with the new complete medium 1:1 as the experimental group for mouse melanoma cell (B16) cell culture; at the same time, set the B16 cells cultured with the new complete medium as a blank group. The total antioxidant capacity of the two groups of B16 cells was measured by using the Biyuntian total antioxidant capacity kit to evaluate whether the adipose stem cell culture medium can increase the level of antioxidant substances in the B16 cells.

[0036] Group Statistics

[0037]

[0038] independent sample test

[0039]

[0040] From the data obtained from the above tests, it can be concluded that the data variances of the experimental group and the control group are equal, Sig=0.006<0.01, thus proving that the adipose stem cell medium can significantly increase the level of antioxidant substances in B16 cells in the ...

Embodiment 2

[0041] Example 2: The protein extract obtained by the concentration-freeze-drying of stem cell culture medium has antioxidant effect when used in cell culture

[0042] The recovered stem cell culture medium is concentrated-lyophilized to obtain the protein in the stem cell culture medium. The obtained protein extract was redissolved in the complete medium, and two concentration gradients of 4mg / ml and 2mg / ml were respectively prepared as the experimental group, and the complete medium without the protein extract was set as the blank group. The above three groups of media were used for the cultivation of dental pulp stem cells, and the total antioxidant capacity of dental pulp stem cells was measured using Beyontian Total Antioxidant Capacity Kit, and whether the protein extract of stem cell culture medium could enhance the antioxidant capacity of dental pulp stem cells material level.

[0043] Group Statistics

[0044]

[0045] Antioxidant capacity

[0046]

[0047] T...

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Abstract

The invention discloses a stem cell treatment matter microneedle for skin antioxidation. The stem cell treatment matter microneedle is composed of a microneedle made of a metal material and stem celltreatment matter, wherein the stem cell treatment matter is a stem cell medium, and stem cells are hematopoietic stem cells, bone marrow stem cells, neural stem cells, amnion stem cells, dental pulp stem cells or uterine membrane stem cells. Compared with intravenous or intramuscular injection, the stem cell treatment matter microneedle for the skin antioxidation reduces the pain of users, is moresimple and convenient in operation, and will not cause environmental pollution; meanwhile, compared with stem cells or stem cell extractive used in the prior art, the stem cell treatment matter microneedle is low in cost and simple in operation, the medium in which the stem cells are cultured is utilized directly, and thus resources are prevented from being wasted.

Description

technical field [0001] The invention relates to the field of stem cell microneedles, in particular to a stem cell treatment microneedle for skin anti-oxidation, which is used for anti-oxidation of the skin and repairing melanin deposited on the skin. Background technique [0002] In 1999, "Science" rated the research results of human embryonic stem cells as the top ten scientific and technological progress in the world that year. In 2000, Time magazine listed it as the top ten scientific and technological achievements in the world at the end of the 20th century. Genome will simultaneously become the most promising field of development and application in the new century. So far, stem cell research has become one of the most striking hot spots in the fields of biology and medicine in recent years. Stem cells (SC) are a kind of pluripotent cells with self-renewing ability, which can differentiate into various functional cells under certain conditions. Stem cells are not fully...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00A61K35/28A61K35/30A61K35/50A61P17/18A61P17/00A61K8/99A61Q19/08A61Q19/02
CPCA61K8/99A61K9/0021A61K35/28A61K35/30A61K35/50A61K2800/91A61M37/0015A61M2037/0023A61M2037/0046A61Q19/02A61Q19/08
Inventor 任怀娟赵鑫王泽剑齐念民
Owner 上海坤爱生物科技股份有限公司
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