Pharmaceutical composition with antalgic function

A composition and pharmacy technology, applied in the field of medicine, can solve the problems of inability to meet usage requirements, general analgesic effect, slow onset of action, etc., and achieve the effects of satisfying usage requirements, good antibacterial effect, and fast onset of action

Inactive Publication Date: 2018-02-16
冯威
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The technical effects provided by this new compound have been improved pain-relieving properties compared to existing drugs while also being effective against bacillus strains that can cause serious illnesses such as tuberculosis or other diseases caused by harmful microorganisms like Escherichia coli (ECO).

Problems solved by technology

The technical problem addressed by this patented technology relates to finding effective ways to manage pain without causing negative side reactions like other types of drug that can cause complications.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1 (preparation one)

[0022] Select:

[0023] 1 part by weight of hyaluronate, which is a combination of sodium hyaluronate or potassium hyaluronate;

[0024] 2 parts by weight of Arnica ethylene glycol extract, the Arnica ethylene glycol extract is extracted from Arnica flowers, and the Arnica ethylene glycol extract is a powder composition;

[0025] 2 parts by weight of polyhydric alcohol, polyhydric alcohol comprises multiple mixed compositions such as glycerin, trimethylolethane, xylitol, sorbitol, ethylene glycol, propylene glycol;

[0026] There are 3 parts by weight of fatty acid or its salt, fatty acid or its salt is selected from: myristoleic acid, palmitoleic acid, hexadecenoic acid, oleic acid, elaidic acid, vacantoleic acid, linoleic acid, elaidic acid , α-linolenic acid, arachidonic acid, eicosapentaenoic acid, erucic acid, docosahexaenoic acid, caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, stearic acid, arachidic acid ...

Embodiment 2

[0034] Embodiment 2 (preparation two)

[0035] 2 parts by weight of hyaluronate, which is a combination of sodium hyaluronate or potassium hyaluronate;

[0036] Arnica ethylene glycol extract 1 part by weight, the arnica ethylene glycol extract is extracted from Arnica flowers, and the arnica ethylene glycol extract is a powder composition;

[0037] 3 parts by weight of polyhydric alcohol, polyhydric alcohol comprises multiple mixed composition such as glycerol, trimethylolethane, xylitol, sorbitol, ethylene glycol, propylene glycol;

[0038] There are 5 parts by weight of fatty acid or its salt, fatty acid or its salt is selected from: myristoleic acid, palmitoleic acid, hexadecenoic acid, oleic acid, elaidic acid, vacantoleic acid, linoleic acid, elaidic acid , α-linolenic acid, arachidonic acid, eicosapentaenoic acid, erucic acid, docosahexaenoic acid, caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, stearic acid, arachidic acid , behenic acid, ligno...

Embodiment 3

[0046] Embodiment 3 (biological experiment)

[0047] 1. Experiment preparation

[0048]First prepare fifty mice, feed them for ten days under the same conditions, prepare the pharmaceutical compositions in Example 1 and Example 2, which are respectively the experimental group 1 and the experimental group 2, and then select two common analgesic drugs on the market Drugs, marked as the control group and the control group two, ten mice were assigned to each of the above four groups, and the remaining ten were blank control groups.

[0049] 2. Conduct experiments

[0050] (1) First feed the mice under the same conditions, and then crack the ribs at the same position on both sides of the back spine of the mice, so that the mice suffer the same damage at the same position;

[0051] (2) The mice in the experimental group 1 and experimental group 2, as well as the control group and the control group 2, applied medicine to the crack site in the morning and evening respectively, with ...

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PUM

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Abstract

The invention discloses a pharmaceutical composition with an antalgic function. The composition comprises the following ingredients (by weight): 0.01-5 parts of hyalurate, 0.5-10 parts of an arnica glycol extract, 1-5 parts of polyol, 0.1-5 parts of fatty acid or salt, 0.1-5 parts of hydroxy propyl cellulose, 1-30 parts of an anti-inflammatory agent, 0.1-20 parts of a copolymer, 0.1-5 parts of poloxamer, 50-90 parts of hydrogel and 0.1-5 parts of distilled water. The formula is simple. The composition has a good antalgic effect, takes effect quickly, has long time of duration, has a good antibacterial effect, has no side-effect, and meets present use requirements.

Description

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Claims

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Application Information

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Owner 冯威
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