Processing method of polygonum multiflorum decoction piece with high content of stilbeneglycoside and free anthraquinone

A technology of stilbene glycosides and free anthraquinone, which is applied in the field of traditional Chinese medicine processing, can solve problems such as hidden dangers in the quality and safety of decoction pieces, achieve the effects of ensuring the curative effect of decoction pieces, simplifying the processing procedure, and reducing the loss of ingredients

Active Publication Date: 2018-05-15
广东汇群中药饮片股份有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the preparation method of multiple exposures may also involve changes in components such as ultraviolet catalysis and light fermentation, as well as efficacy and toxicity.
However, in order to promote it to large-scale production, modern technology simplifies the nine-steaming and nine-exposure method to steaming once, without exposure to sunlight. Why does the quality of the decoction pieces of Shouwu bring safety hazards?

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A method for processing Polygonum multiflorum decoction pieces with high content of stilbene glycosides and free anthraquinone, comprising the following steps:

[0018] Quantitatively weigh black beans, add 12 times the amount of water, boil for 4 hours, filter; then add 8 times the amount of water to the bean dregs, boil for 3 hours, filter, combine to obtain black bean juice, and then reduce and concentrate under reduced pressure to obtain 14 times of black beans The amount of black bean juice concentrate, set aside. Wash the Polygonum multiflorum to remove impurities, and select Polygonum multiflorum with similar specifications for drying and slicing. Add an appropriate amount of black bean juice concentrate and moisten thoroughly to obtain Polygonum multiflorum slices for soybean preparation; after soaking with black bean juice concentrate, put it in a steam pressure cooker for high-pressure steaming. The steaming conditions are pressure 0.1 MPa, temperature 120°C, ...

Embodiment 2

[0020] A method for processing Polygonum multiflorum decoction pieces with high content of stilbene glycosides and free anthraquinone, comprising the following steps:

[0021] Quantitatively weigh black beans, add 12 times the amount of water, boil for 4 hours, filter; then add 8 times the amount of water to the bean dregs, boil for 3 hours, filter, combine to obtain black bean juice, and then reduce and concentrate under reduced pressure to obtain 14 times of black beans The amount of black bean juice concentrate, set aside. Wash the Polygonum multiflorum to remove impurities, and select Polygonum multiflorum with similar specifications for drying and slicing. Add an appropriate amount of black bean juice concentrate and moisten thoroughly to obtain Polygonum multiflorum slices for soybean preparation; after soaking with black bean juice concentrate, put it in a steam pressure cooker for high-pressure steaming. The steaming conditions are pressure 0.1 MPa, temperature 120°C, ...

Embodiment 3

[0023] A method for processing Polygonum multiflorum decoction pieces with high content of stilbene glycosides and free anthraquinone, comprising the following steps:

[0024] Quantitatively weigh black beans, add 12 times the amount of water, boil for 4 hours, filter; then add 8 times the amount of water to the bean dregs, boil for 3 hours, filter, combine to obtain black bean juice, and then reduce and concentrate under reduced pressure to obtain 14 times the amount of black beans The amount of black bean juice concentrate, set aside. Wash the Polygonum multiflorum to remove impurities, and select Polygonum multiflorum with similar specifications for drying and slicing. Add an appropriate amount of black bean juice concentrate and moisten thoroughly to obtain Polygonum multiflorum slices for soybean preparation; after soaking with black bean juice concentrate, put it in a steam pressure cooker for high-pressure steaming. The steaming conditions are pressure 0.1MPa, temperatu...

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PUM

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Abstract

The invention discloses a processing method of a polygonum multiflorum decoction piece with a high content of stilbeneglycoside and free anthraquinone. The processing method comprises the steps of cleaning, drying and slicing polygonum multiflorum, adding black soya bean juice concentrated liquid for thorough moistening, performing high pressure steaming and high-voltage electric field drying to form preliminarily processed polygonum multiflorum, repeating the thorough moistening, the steaming and drying for many times for the preliminarily processed polygonum multiflorum to form the radix polygonum multiflorum preparata decoction piece with a high active ingredient content and low toxicity. The traditional and modern technologies are combined; the toxicity of the polygonum multiflorum isreduced by processing for many times; the active ingredient content is increased via a modern high-pressure steaming technology and a high-voltage electric field drying technology; a curative effect of the prepared radix polygonum multiflorum preparata decoction piece is better than that of a radix polygonum multiflorum preparata decoction piece processed by the traditional technique; toxic and side effects of the decoction piece are lower than those of the decoction piece processed by a modern processing technique; and the prepared radix polygonum multiflorum preparata decoction piece is highin safety.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine processing, in particular to a processing method of Polygonum multiflorum. Background technique [0002] In recent years, the reports on liver injury caused by Polygonum multiflorum have increased rapidly, and the drug regulatory authorities in the United Kingdom, Australia, Canada, Japan and my country have successively issued warnings or regulatory measures on the risk of liver injury in Polygonum multiflorum and its preparations, which has aroused great concern at home and abroad. Studies have shown that processing is an important factor affecting the efficacy / toxicity of Polygonum multiflorum. In ancient times, it was emphasized that Polygonum multiflorum "controls non-nine times, and it is poisonous." Modern experimental studies have also confirmed that processing can significantly reduce the side effects of Polygonum multiflorum. However, the modern processing method of Polygonum ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61K36/48
CPCA61K36/48A61K36/704A61K2236/10A61K2236/17
Inventor 李妙霞李春泉陈一村
Owner 广东汇群中药饮片股份有限公司
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