Monoclonal antibody for identifying monohydroxy phenolic compound as well as preparation method and application thereof

A monoclonal antibody, monohydric phenol technology, used in biochemical equipment and methods, chemical instruments and methods, microorganisms, etc.

Active Publication Date: 2018-08-10
JINAN TAIHE PHARM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Currently commonly used tumor inducing factors include smoking, drinking, etc., but these risk factors...

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  • Monoclonal antibody for identifying monohydroxy phenolic compound as well as preparation method and application thereof
  • Monoclonal antibody for identifying monohydroxy phenolic compound as well as preparation method and application thereof
  • Monoclonal antibody for identifying monohydroxy phenolic compound as well as preparation method and application thereof

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Embodiment Construction

[0094] The present invention will be described in further detail below in conjunction with the accompanying drawings: the present embodiment is implemented on the premise of the technical solution of the present invention, and detailed implementation is provided, but the protection scope of the present invention is not limited to the following embodiments.

[0095] A monoclonal antibody that recognizes monohydric phenolic compounds, the nucleic acid sequence information of the heavy chain coding region of the monoclonal antibody is encoded by the DNA sequence shown in SEQ 1; the amino acid of the heavy chain coding region of the monoclonal antibody The sequence information is encoded by the amino acid sequence shown in SEQ 2;

[0096] The nucleic acid sequence information of the light chain coding region of the monoclonal antibody is encoded by the DNA sequence shown in SEQ 9; the amino acid sequence information of the light chain coding region of the monoclonal antibody is enc...

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Abstract

The invention relates to a monoclonal antibody for identifying a monohydroxy phenolic compound. The nucleotide sequence information of a heavy chain coding region is encoded by DNA sequence shown as SEQ 1; the amino acid sequence information of the heavy chain coding region is encoded by amino acid sequence shown as SEQ 2; the nucleic acid sequence information of a light chain coding region is encoded by the DNA sequence shown as SEQ 9; the amino acid sequence information of the light chain coding region is encoded by amino acid sequence shown as SEQ 10. The monoclonal antibody for identifyingthe monohydroxy phenolic compound has the advantages that the monohydroxy phenolic compound in human body fluid can be detected; the immunity state of the body and the activity degree of cells in thebody of a testee can be reflected through the content of the monohydroxy phenolic compound, so that the early diagnosis of tumor is facilitated. The monoclonal antibody for identifying the monohydroxy phenolic compound can be used for effectively detecting gastrointestinal tumors such as gastric cancer, colon cancer, rectal cancer, esophagus cancer and pancreatic cancer.

Description

technical field [0001] The invention relates to the field of monoclonal antibodies, in particular to a monoclonal antibody that recognizes monohydric phenolic compounds and its preparation method and application. Background technique [0002] Cancer has become the main cause of human death in the world. Most cancer patients are at an advanced stage when the cancer is diagnosed, and with the improvement of tumor progression, patients are always accompanied by a serious imbalance in nutritional status, which may seriously affect cancer. High morbidity and mortality among patients. Currently commonly used tumor inducing factors include smoking, drinking, etc., but these risk factors cannot provide any scientific interpretation for the biological characterization of early tumor progression. Tumor epidemiological survey data show that 45% of cancer patients lose more than 10% of their body weight, and 25% of cancer patients lose more than 20% of their body weight. In patients w...

Claims

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Application Information

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IPC IPC(8): C07K16/44G01N33/574C12N5/20
CPCC07K16/44C07K2317/565G01N33/574
Inventor 李漪娜
Owner JINAN TAIHE PHARM TECH CO LTD
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