Monoclonal antibody for identifying monohydroxy phenolic compound as well as preparation method and application thereof

Abstract

The invention relates to a monoclonal antibody for identifying a monohydroxy phenolic compound. The nucleotide sequence information of a heavy chain coding region is encoded by DNA sequence shown as SEQ 1; the amino acid sequence information of the heavy chain coding region is encoded by amino acid sequence shown as SEQ 2; the nucleic acid sequence information of a light chain coding region is encoded by the DNA sequence shown as SEQ 9; the amino acid sequence information of the light chain coding region is encoded by amino acid sequence shown as SEQ 10. The monoclonal antibody for identifyingthe monohydroxy phenolic compound has the advantages that the monohydroxy phenolic compound in human body fluid can be detected; the immunity state of the body and the activity degree of cells in thebody of a testee can be reflected through the content of the monohydroxy phenolic compound, so that the early diagnosis of tumor is facilitated. The monoclonal antibody for identifying the monohydroxy phenolic compound can be used for effectively detecting gastrointestinal tumors such as gastric cancer, colon cancer, rectal cancer, esophagus cancer and pancreatic cancer.

Description

technical field [0001] The invention relates to the field of monoclonal antibodies, in particular to a monoclonal antibody that recognizes monohydric phenolic compounds and its preparation method and application. Background technique [0002] Cancer has become the main cause of human death in the world. Most cancer patients are at an advanced stage when the cancer is diagnosed, and with the improvement of tumor progression, patients are always accompanied by a serious imbalance in nutritional status, which may seriously affect cancer. High morbidity and mortality among patients. Currently commonly used tumor inducing factors include smoking, drinking, etc., but these risk factors cannot provide any scientific interpretation for the biological characterization of early tumor progression. Tumor epidemiological survey data show that 45% of cancer patients lose more than 10% of their body weight, and 25% of cancer patients lose more than 20% of their body weight. In patients w...

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Problems solved by technology

Currently commonly used tumor inducing factors include smoking, drinking, etc., but these risk factors cannot provide any scientific interpretation for the biological characterization of early tumor progression

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