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Human peripheral blood T cell immune function simplified evaluation kit and evaluation method

A technology of cellular immunity and peripheral blood, applied in the medical field, can solve problems such as the lack of methods for comprehensively evaluating the immune function of human T cells, and achieve the effects of improving health status, improving immune function, and being easy to use

Inactive Publication Date: 2019-01-22
东莞暨南大学研究院
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Problems solved by technology

[0005] At present, neither clinical nor third-party testing institutions have a method that can comprehensively evaluate the immune function of human T cells

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  • Human peripheral blood T cell immune function simplified evaluation kit and evaluation method

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Embodiment Construction

[0029] As used herein:

[0030] "Prepared from" is synonymous with "comprising". As used herein, the terms "comprises," "including," "has," "containing," or any other variation thereof, are intended to cover a non-exclusive inclusion. For example, a composition, step, method, article, or device comprising listed elements is not necessarily limited to those elements, but may include other elements not explicitly listed or inherent to such composition, step, method, article, or device. element.

[0031] The conjunction "consisting of" excludes any unspecified elements, steps or components. If used in a claim, this phrase will make the claim closed so that it does not contain material other than those described except for the customary impurities associated therewith. When the phrase "consisting of" appears in a clause of the subject of a claim rather than immediately following the subject matter, it only defines the elements described in that clause; other elements are not ex...

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Abstract

The invention provides a human peripheral blood T cell immune function simplified evaluation kit and evaluation method. The human peripheral blood T cell immune function simplified evaluation kit comprises an anti-human CD3 antibody with a first fluorescein label, an anti-human CD25 antibody with a second fluorescein label, an anti-human CD4 antibody with a third fluorescein label, an anti-human CD8 antibody with a fourth fluorescein label, an anti-human CD45RA antibody with a fifth fluorescein label, an anti-human CCR7 antibody with a sixth fluorescein label, an anti-human CD28 antibody witha seventh fluorescein label, and an anti-human CD127 antibody with an eighth fluorescein label. The human peripheral blood T cell immune function simplified evaluation kit provided by invention can beused for comprehensive evaluation of the immune function of the human peripheral blood T cells, which is convenient to use, and is safe for a human body.

Description

technical field [0001] The invention relates to the medical field, in particular to a simplified evaluation kit and evaluation method for human peripheral blood T cell immune function. Background technique [0002] T lymphocytes are derived from pluripotent stem cells of the bone marrow (the embryonic stage is derived from the yolk sac and liver). During the embryonic and nascent stages of the human body, a part of pluripotent stem cells or pre-T cells in the bone marrow migrate into the thymus, differentiate and mature under the induction of thymus hormones, and become immune-competent T cells. [0003] Mature T cells are distributed through the bloodstream to settle in the thymus-dependent areas of peripheral immune organs, and can be recirculated through lymphatic vessels, peripheral blood, and tissue fluid to exert cellular immunity and immune regulation functions. The recycling of T cells is conducive to extensive exposure to antigenic substances entering the body, str...

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Application Information

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IPC IPC(8): G01N33/569
CPCG01N33/56966G01N2333/7051G01N2333/70514G01N2333/70517G01N2333/70521G01N2333/70589G01N2333/715
Inventor 尹芝南吴扬哲
Owner 东莞暨南大学研究院
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