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A mechanical perfusion system for preservation of isolated kidneys

An isolated and mechanical technology, applied in the field of kidney transplantation, can solve the problems of static cold preservation technology, difficult to preserve and transport multiple organs, and achieve the effect of alleviating renal reperfusion injury and ensuring the life activity of the kidney

Active Publication Date: 2021-06-25
杭州莱普晟医疗科技有限公司
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  • Abstract
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AI Technical Summary

Problems solved by technology

[0005] The invention provides a mechanical perfusion system for the preservation of isolated kidneys, which solves the problem of preservation and transportation of multiple organs that is difficult to solve in the existing static cold preservation technology

Method used

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  • A mechanical perfusion system for preservation of isolated kidneys
  • A mechanical perfusion system for preservation of isolated kidneys

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Embodiment Construction

[0040] Such as figure 1 Shown is the working state of a mechanical perfusion system for isolated kidneys preserved by the present invention, including: a peristaltic pump (1), a filter (2), a main line pressure sensor (3), a sampling valve (4), a T Type pipeline bifurcation buffer box (5), main pipeline air bubble sensor (6), kidney A branch air bubble sensor (7), kidney B branch air bubble sensor (8), exhaust branch solenoid valve (9), kidney A branch solenoid valve (10), kidney B branch solenoid valve (11), kidney A branch flow sensor (13), kidney B branch flow sensor (12), kidney A branch pressure sensor (15), kidney B branch pressure sensor (14), temperature control tank (16), perfusate storage box (18), kidney A storage tank (17), kidney B storage tank (21), kidney A (20), kidney B (22 ), a kidney A interface (19), a kidney B interface (24), a control unit (23), and a display unit (25).

[0041]1) The mechanical perfusion system for the preservation of the isolated kidn...

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Abstract

The present invention relates to a mechanical perfusion system for the preservation of isolated kidneys. The system includes: (1) a temperature-controlled tank for containing perfusate; (2) two sets of tanks for containing isolated kidneys. Isolated kidney storage tank; (3) A pipeline connected between the perfusate temperature-controlled tank and the isolated kidney storage tank and used to deliver perfusate to the isolated kidney; (4) A pressure tube used to detect the pressure of the pipeline detection module; (5) a flow detection module used to detect pipeline flow; (6) an air bubble detection module used to detect pipeline air bubbles; (7) a solenoid valve module used to control night circuit on-off; (8) (9) A control module used to control the peristaltic pump and solenoid valve module; (10) A display module used to display pipeline pressure, flow rate, and resistance coefficient of kidney organs.

Description

technical field [0001] The invention belongs to the technical field of kidney transplantation, and in particular relates to a mechanical perfusion system for preservation of isolated kidneys. Background technique [0002] Kidney transplantation technology is the most effective therapy for end-stage renal disease. With the advancement of immune tolerance technology, the application of regulatory T cells (Treg) in the field of kidney transplantation, and the effective control of cell-mediated rejection, kidney transplantation Recipient survival rate continues to improve. With the official launch of organ donation after the death of citizens in my country, there is still a shortage of kidney organ sources. severe. However, the risk of PNF and delayed recovery of graft function (DGF) in marginal donor organ transplantation is higher. [0003] At present, the static cold preservation method is used for clinical donor kidneys. This method has the advantages of simple operation, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N1/02
Inventor 李建辉邵光业黄光涛杨子江辛立明
Owner 杭州莱普晟医疗科技有限公司
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