80 results about "Two kidney" patented technology

The invention discloses a method and a system for constructing a renal function automatic estimation model based on plain-scan CT (Computed Tomography). The method comprises the following steps: S1, collecting image data of a patient suffering from renal atrophy or hydronephrosis; s2, training a kidney parenchyma and hydronephrosis region automatic segmentation model based on UNETR by using kidney parenchyma and hydronephrosis regions manually described by a radiologist; s3, image omics features are extracted from the images, and data are screened; s4, constructing a renal function index regression model, wherein the renal function index regression model comprises a GFR regression model and an SRF regression model; s5, verifying an estimated value of the regression model; and S6, calculating GFR and SRF by using the renal function index regression model, and distinguishing kidneys in different health states. By adopting the method, the glomerular filtration rate and the lateral renal function of each kidney can be automatically estimated. A rapid, convenient and low-cost renal function evaluation method is provided for treating patients with renal atrophy or hydronephrosis.

A computer-implemented method that includes processing a EIT data set of a subject to determine one or more kidney-related conductivity characteristics of the subject, and, determining, based on at least the one or more determined kidney-related conductivity characteristics of the subject, a health state or condition of the at least one kidney of the subject.

The invention discloses a renal puncture AI auxiliary data processing method and system based on artificial intelligence, and the method comprises the steps: obtaining an ultrasonic image containing a kidney and internal blood vessels, and carrying out the noise suppression and contrast enhancement processing of the ultrasonic image; performing blood vessel region segmentation on blood vessels in the kidney in the ultrasonic image, and placing the segmented blood vessel region in a predefined rectangular frame; fuzzy motion caused by probe shaking in the predefined rectangular frame is corrected; inputting the ultrasonic image in the predefined rectangular frame into a trained kidney blood vessel segmentation model to obtain an ultrasonic image sequence containing an upper boundary line and a lower boundary line of the kidney; wherein the upper boundary line is positioned above the blood vessel and below the upper contour of the kidney; the lower boundary separates the lower contour of the kidney from the blood vessel; and outputting the ultrasonic image sequence to a kidney puncture auxiliary system for a doctor to use in a kidney puncture process. The upper boundary line and the lower boundary line of the kidney can be accurately recognized and extracted, and puncture accuracy and safety are improved.

The invention discloses a kidney function prediction method and device, electronic equipment and a medium. The method comprises the steps that a kidney cortical medullary enhancement period image of a target patient is acquired; inputting a kidney cortical medullary enhancement stage image of the target patient into the trained segmentation model to segment a cortical region in the cortical medullary enhancement stage image to obtain a cortical region image of the kidney of the target patient; extracting radiation group features of the cortex region image; and inputting the radiation group features of the cortex region image into the trained renal function staging prediction model, and predicting the renal function staging of the target patient. The invention assesses renal function by a non-invasive and reliable alternative method.

The present invention concerns selective renal denervation treatment of drug resistant hypertensive patients by correlating the patients' genetic panel by categorization and hierarchy according to patients' genetic variants within the functional genes for heart activity, for the renin-angiotensin aldosterone system, and for renal activity.

The present application provides a system for guided removal of particulate matter from a body of a subject, in particular a system for removing a plurality of small stone fragments from a kidney of a subject. The system comprises a ureter kidney access sheath, a kidney perfusion catheter, an imaging device and a double-acting pumping device. The ureteral kidney access sheath includes a fluid discharge port connected to a double-acting pumping device. The kidney perfusion catheter includes a fluid inlet port connected to the double-acting pumping device. Also disclosed is a method for removing particulate matter from a kidney of a subject, the method comprising using the system.

In an illustrative embodiment, systems and methods for treating kidney disease in a human patient are disclosed. A method includes advancing a collapsible array of RF electrodes through a urinary tract of the patient in collapsed form and into a position in or near a renal pelvis. The effector is deployed to an expanded form to engage at least a portion of an interior wall of the renal pelvis. RF energy delivered through the array of electrodes target afferent nerves proximate the interior wall of the renal pelvis to inhibit or destroy their function. eGFR of the patient can be raised after treatment according to the method.

The invention discloses a kidney blood perfusion device used before kidney ischemia, and relates to the field of perfusion devices, the kidney blood perfusion device comprises a machine shell, the side face of the machine shell is provided with a pair of fasteners, and the fasteners are used for fixing syringes respectively; the movable plate is arranged in the machine shell through a moving mechanism, and the moving mechanism can drive the movable plate to move in the machine shell; the pushing parts are arranged on the movable plate and used for pushing a piston handle in the injector, each pushing part comprises a sliding sleeve, a movable sleeve and an elastic component, the sliding sleeves are arranged on the side face of the movable plate, and the movable sleeves are inserted into the sliding sleeves in a sliding mode. The device has the advantages that manual time sequence errors in operation are avoided through double-stage strict separation, reperfusion after blood vessels are closed is ensured, a mechanical interlocking mechanism of a blocking pad and a stroke strip forcibly requires that perfusion can be started only after liquid bag expansion is completed, and the misoperation risk is completely eradicated from the hardware level; the double-stage seamless switching of liquid injection expansion and perfusion is realized, the efficiency is high, the perfusion speed of mechanical pushing injection during perfusion is more uniform, and the effect is better.

Methods and systems provide a human kidney perfusion model with dual blood supply channels, permitting two kidneys from the same donor to be pumped simultaneously for rigorously controlled therapeutic testing.

1. Name of the product in this design: Kidney cryogenic perfusion transport box. 2. Purpose of this design: for the perfusion, preservation and transport of kidney organs. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

Methods for treating a patient using therapeutic renal neuromodulation and associated devices, system, and methods are disclosed herein. One aspect of the present technology is directed to neuromodulating nerve tissue in selected anatomical regions. In one embodiment, the method can include intravascularly advancing an elongate shaft of a catheter to renal vasculature of a human patient and locating a first neuromodulation element of the catheter within a distalmost portion of a main renal artery. The method includes locating a second neuromodulation element of the catheter within a branch vessel of the renal artery distal to a bifurcation at a distal end of the main renal artery. Neuromodulation of the nerve tissue surrounding the selected anatomical treatment locations can inhibit sympathetic neural activity in nerves proximate a portion of a renal artery and / or a renal branch artery proximate a renal parenchyma.

The present application discloses an artificial kidney. An implantable or wearable kidney enclosure is cylindrical, oval or other non-angular (e.g., non-rectangular or non-cubic) and has a circular or elliptical blood filter that provides a blood flow pattern radially outward from an internal central arterial source. Due to the efficient flow of the circular filter design, the enclosure can be made into a cylindrical low-profile shape, thereby forming a compact enclosure that is very suitable for implantable and wearable dialysis applications.

An intravascular catheter for nerve activity ablation and / or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes at the distal ends of the guide tubes allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered to ablate nerves outside of the media.

Disclosed herein are systems and methods for treating certain medical conditions by implanting a specialized implant within a patient and applying electrical current, ultrasound, or both to a kidney or locations adjacent to a kidney to stimulate kidney activity. In some examples, electroporation, sonoporation, and / or transient nerve block may be created to selectively improve kidney function and thereby treat a variety of different diseases.

The utility model belongs to the field of ureter guiding sheaths, particularly relates to a ureter guiding sheath capable of reducing internal pressure of a renal pelvis and pressure of a bladder, and aims to solve the problems that when an existing guiding sheath injects water into a kidney during an operation, the pressure of the kidney is too large, water flows back into blood, infection risk is increased, and the operation time is prolonged. Liquid in the bladder is gradually increased, bladder pressure is increased, the bladder is overfilled, and the bladder function is damaged. According to the scheme, the catheter comprises a guide sheath tube, a bendable catheter is arranged at the front end of the guide sheath tube, a plurality of evenly-distributed second holes are formed in the outer portion, away from the bendable catheter, of the guide sheath tube, and a plurality of evenly-distributed first holes are formed in the outer portion of the front end of the bendable catheter and the outer portion of the front end of the guide sheath tube. Through the arrangement of the first hole and the second hole, liquid in the kidney and the bladder can be further drained out of the body through the liquid passing ability of the measuring holes, the pressure in the kidney and the pressure of the bladder are effectively relieved, and it is ensured that drainage is more sufficient and effective.

The invention provides an SPECT / CT-based renal function determination method and device and a processing system, designs a novel renal function determination architecture, and combines a CT structure image to more accurately distinguish kidney tissues and perirenal tissues and extract more real double-kidney signals compared with a traditional scheme that SPECT images are used for sketching double-kidney ROI (Region of Interest). The high time resolution and the high spatial resolution are both considered, so that the time radioactivity curve and the glomerular filtration rate of the separated kidney can be accurately measured, the high-quality measurement requirement for the separated kidney function in clinical work is met, and high-quality diagnosis and treatment service can be provided for a patient.

Provided herein are perfusion systems (e.g., a perfusion system with an acoustic volume sensor) that deliver a composition comprising at least one agent that induces expression of OCT3 / 4, SOX2, c-MYC, KLF4, N.ANOG, and / or LIN28 in the kidney. Also provided herein are methods and compositions suitable for use with the perfusion systems.

This invention discloses a laparoscopic kidney gripper, comprising a barrel for passing through a laparoscope into the human body and a shell-like body connected thereto; the barrel is retractably fitted with several proximal negative pressure mechanisms and distal traction tubes for adsorbing the kidney; a control mechanism for adjusting the extension and retraction of the traction tubes is installed inside the gun body. Compared to the prior art that uses rigid laparoscopic gastric or intestinal forceps to grip the kidney, this application uses negative pressure suction to form a connection, thereby avoiding slippage and compression damage to the kidney that may occur during clamping connections, thus reducing the difficulty of operation for doctors and the risk of kidney damage to patients.

The invention discloses a Renal scoring method and device for kidney tumors, and belongs to the field of medical image processing. The method comprises the steps that segmentation data are acquired, and the segmentation data comprise data of kidneys, tumors and blood vessels; anatomical analysis is carried out based on the segmentation data, the kidney principal axis, the renal pelvis position and the ureter are determined, and a natural coordinate system of the kidney is established; calculating the maximum diameter of the tumor based on the tumor voxel, and determining an R score according to the maximum diameter of the tumor; constructing a kidney convex hull based on the kidney parenchyma coordinates, and determining an E score based on the proportion of tumor voxels inside and outside the kidney convex hull; taking the ureter as a set system, determining the minimum distance from the tumor voxel to the set system, and determining an N score according to the minimum distance; constructing a natural interface based on the pelvis position, and determining an A score based on the natural interface; detecting polar lines based on the renal door depression, and determining an L score according to the polar lines. The method provided by the invention eliminates the subjective judgment difference of the scorer.

The present application discloses and claims a kidney phantom consisting of a silicone rubber model featuring the anatomical shape of a human kidney, the renal artery, the renal vein, and a total of 11 tumors and 2 cysts. Each tumor is represented by a solid mass, while cysts are empty three-dimensional shapes. In order to accommodate the needs of both novice and advanced surgeons, tumors were designed with increasing surgical difficulty. The kidney phantom disclosed in the present application can be combined with a commercially available ensemble of laparoscopic tools to provide localized and remote training to surgeons and medical staff practicing laparoscopic and robotic partial nephrectomy.

The utility model discloses an anti-reflux ureteral stent, which belongs to the technical field of ureteral stents and comprises a stent pelvis section, a stent ureteral section and a stent bladder section. At least one hollow expansion part is arranged on the tube wall of the bladder section of the stent, and an integrated anti-reflux valve is arranged in a tube cavity of the expansion part. The valve is composed of a plurality of valve-shaped structures, the free ends of the valve-shaped structures can be close to each other to seal a lumen when subjected to retrograde liquid pressure from the bladder to the kidney, the free ends of the valve-shaped structures are separated from each other to open the lumen when subjected to forward liquid pressure from the kidney to the bladder, and therefore one-way drainage of urine is achieved. The anti-backflow urine bag is simple in structure and capable of effectively preventing backflow of urine and complications such as lumbago and hydronephrosis caused by backflow of urine. Meanwhile, due to the structure of the expansion part, the valve can be completely attached to the wall when opened, and operation smoothness and safety are guaranteed when a guide wire is placed in.

A method of treating a renal condition by topical region perfusion of one or both kidneys of a patient is disclosed. A closed circuit is formed with a perfusion catheter positioned in the renal artery of the kidney, a recovery catheter positioned in the renal vein of the kidney, and an extracorporeal membrane oxygenator disposed therebetween. Perfusate containing, for example, a gene therapy drug may circulate through the closed circuit while isolating the closed circuit from the systemic circulation of the patient.

The invention provides a novel three-dimensional virtual model-assisted partial renal resection artery occlusion strategy optimization method, and relates to the technical field of artificial intelligence, medical image processing and application, in particular to a novel three-dimensional virtual model-assisted partial renal resection artery occlusion strategy optimization method. The method comprises the following steps of: firstly, processing original image data scanned by CT (Computed Tomography) by utilizing M3DICS three-dimensional reconstruction software, and obtaining a corresponding digital kidney three-dimensional model; secondly, the kidney three-dimensional model is combined with a mathematical algorithm, the kidney parenchyma volume is divided into blood vessel perfusion areas of the kidney parenchyma volume, a new three-dimensional virtual kidney model with different perfusion areas is generated, artery branches needing to be clamped when selective occlusion is possibly carried out are recorded based on the modeling result, selective occlusion simulation is carried out, and the blood vessel perfusion areas of the kidney are simulated; and an accurate and benefit-maximized treatment scheme is formulated for the object.

This invention belongs to the field of medical image processing technology, specifically relating to a kidney segmentation method based on key point localization. The method includes the following steps: acquiring medical images of the kidney to be segmented and preprocessing the images; defining a set of anatomical key points specifically for kidney segmentation; predicting the position coordinates of each key point in the key point set using a model; constructing spatial topological relationships between key points based on the predicted key point coordinates and kidney anatomical zoning rules; and dividing the kidney parenchyma into regions according to the spatial topological relationships and kidney anatomical zoning rules, outputting the segmentation results for each kidney segment. This invention achieves efficient and accurate automatic kidney segmentation by precisely detecting anatomical key points and combining them with the anatomical rules of the Graves kidney segment model, outputting segmentation results with anatomical interpretability, and providing reliable technical support for preoperative planning of urological surgeries such as precise nephrectomy.

The invention relates to the technical field of image processing, in particular to a method for evaluating the renal function of a nephrotic patient through diffusion tensor imaging. The method comprises the following steps: acquiring a kidney diffusion tensor original image through single excitation echo plane imaging; adjacent comparison is carried out on each pixel point, and a signal intensity difference and a gradient direction difference are extracted; judging local geometric distortion according to the difference information, and carrying out correction processing pixel by pixel to obtain a corrected high-quality diffusion tensor image; and finally, calculating a fitting tensor, extracting diffusion parameters of the renal cortex and the renal medullary region, quantitatively comparing the diffusion parameters with preset renal function indexes, and outputting an objective quantitative result of the renal function of the patient. According to the method, through pixel-by-pixel distortion correction and direction feature extraction, the precision of the diffusion tensor image and the accuracy of kidney region division are improved, and objective quantitative analysis of kidney functions is realized.

The utility model belongs to the technical field of medical equipment, and provides a home body position calculus removal guiding device which comprises a fixed base, a movable base and a guide rod. The kidney model is arranged on the fixed base, a ureter is arranged on the kidney model, and the kidney model is a transparent material model; a renal pelvis cavity, a kidney large calyx cavity and a kidney small calyx cavity are formed in the kidney model, and the ureter, the renal pelvis cavity, the kidney large calyx cavity and the kidney small calyx cavity are used for simulating the ureter, the renal pelvis, the kidney large calyx and the kidney small calyx of the human kidney respectively. The transparent kidney model is convenient for the patient to intuitively observe the movement track of the stone-like member in the kidney model under different body positions. When the kidney model is used, a patient can wear the kidney model at the preset position of the waist, and the body position is changed according to the dynamic condition of the stone-like piece in the kidney model until the stone-like piece is discharged out of the pelvis. Therefore, the cost of the body position drainage bed for the patient is reduced, the hospital return frequency of the patient is reduced, and the body position calculus removing efficiency of the patient is improved.

The invention discloses a biomarker for detecting renal fibrosis, application and a system, and relates to the technical field of biological medicines. The invention relates to a biomarker for detecting renal fibrosis. The biomarker comprises urinary copper cyanin. Compared with the conventional diagnostic marker (such as eGFR, RBP, NAG and the like), the urocyanin has the following three advantages: 1, compared with the conventional diagnostic marker (such as eGFR, RBP, NAG and the like), the urocyanin is more sensitive to diagnosis of renal interstitial fibrosis and fibrosis severity; secondly, compared with traumatic renal tissue pathologic biopsy, urine is used as a diagnosis medium, so that true noninvasive effect can be realized, and no harm is caused to the body health of a patient; and thirdly, compared with detection means such as iconography, the method for detecting the urinary cupreocyanin marker is lower in cost, more flexible, high in timeliness and easier to popularize.

It is an object of the present invention to provide a combination of a functional assessment of renal function together with biomarker results in order to improve assessment of patient at risk of, or having, an acute kidney injury. A loop diuretic such as furosemide inhibits luminal active chloride transport throughout the thick ascending limb of Henle, thereby preventing sodium reabsorption and resulting in natriuresis and increased urine flow. Loop diuretic-induced increases in urine output might be a method to assess the integrity of the renal tubular function in the setting of early AKI, and so a kidney's response, or lack thereof, to a diuretic challenge as a clinical assessment of tubular function can identify patients with severe tubular injury before it is clinically apparent (e.g. a rise in creatinine).

Systems and methods for renal access and pressure reduction. In one or more embodiments, there are provided various systems and methods to reduce renal pressures. In one or more aspects, there are provided devices and methods for the removal or reduction of a capsular constriction to reduce renal pressures such as by one or more of removing fluid or tissue.