58 results about "Two kidney" patented technology

The invention discloses a renal puncture AI auxiliary data processing method and system based on artificial intelligence, and the method comprises the steps: obtaining an ultrasonic image containing a kidney and internal blood vessels, and carrying out the noise suppression and contrast enhancement processing of the ultrasonic image; performing blood vessel region segmentation on blood vessels in the kidney in the ultrasonic image, and placing the segmented blood vessel region in a predefined rectangular frame; fuzzy motion caused by probe shaking in the predefined rectangular frame is corrected; inputting the ultrasonic image in the predefined rectangular frame into a trained kidney blood vessel segmentation model to obtain an ultrasonic image sequence containing an upper boundary line and a lower boundary line of the kidney; wherein the upper boundary line is positioned above the blood vessel and below the upper contour of the kidney; the lower boundary separates the lower contour of the kidney from the blood vessel; and outputting the ultrasonic image sequence to a kidney puncture auxiliary system for a doctor to use in a kidney puncture process. The upper boundary line and the lower boundary line of the kidney can be accurately recognized and extracted, and puncture accuracy and safety are improved.

The invention discloses a kidney function prediction method and device, electronic equipment and a medium. The method comprises the steps that a kidney cortical medullary enhancement period image of a target patient is acquired; inputting a kidney cortical medullary enhancement stage image of the target patient into the trained segmentation model to segment a cortical region in the cortical medullary enhancement stage image to obtain a cortical region image of the kidney of the target patient; extracting radiation group features of the cortex region image; and inputting the radiation group features of the cortex region image into the trained renal function staging prediction model, and predicting the renal function staging of the target patient. The invention assesses renal function by a non-invasive and reliable alternative method.

The present invention concerns selective renal denervation treatment of drug resistant hypertensive patients by correlating the patients' genetic panel by categorization and hierarchy according to patients' genetic variants within the functional genes for heart activity, for the renin-angiotensin aldosterone system, and for renal activity.

In an illustrative embodiment, systems and methods for treating kidney disease in a human patient are disclosed. A method includes advancing a collapsible array of RF electrodes through a urinary tract of the patient in collapsed form and into a position in or near a renal pelvis. The effector is deployed to an expanded form to engage at least a portion of an interior wall of the renal pelvis. RF energy delivered through the array of electrodes target afferent nerves proximate the interior wall of the renal pelvis to inhibit or destroy their function. eGFR of the patient can be raised after treatment according to the method.

The invention discloses a kidney blood perfusion device used before kidney ischemia, and relates to the field of perfusion devices, the kidney blood perfusion device comprises a machine shell, the side face of the machine shell is provided with a pair of fasteners, and the fasteners are used for fixing syringes respectively; the movable plate is arranged in the machine shell through a moving mechanism, and the moving mechanism can drive the movable plate to move in the machine shell; the pushing parts are arranged on the movable plate and used for pushing a piston handle in the injector, each pushing part comprises a sliding sleeve, a movable sleeve and an elastic component, the sliding sleeves are arranged on the side face of the movable plate, and the movable sleeves are inserted into the sliding sleeves in a sliding mode. The device has the advantages that manual time sequence errors in operation are avoided through double-stage strict separation, reperfusion after blood vessels are closed is ensured, a mechanical interlocking mechanism of a blocking pad and a stroke strip forcibly requires that perfusion can be started only after liquid bag expansion is completed, and the misoperation risk is completely eradicated from the hardware level; the double-stage seamless switching of liquid injection expansion and perfusion is realized, the efficiency is high, the perfusion speed of mechanical pushing injection during perfusion is more uniform, and the effect is better.

1. Name of the product in this design: Kidney cryogenic perfusion transport box. 2. Purpose of this design: for the perfusion, preservation and transport of kidney organs. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The utility model belongs to the field of ureter guiding sheaths, particularly relates to a ureter guiding sheath capable of reducing internal pressure of a renal pelvis and pressure of a bladder, and aims to solve the problems that when an existing guiding sheath injects water into a kidney during an operation, the pressure of the kidney is too large, water flows back into blood, infection risk is increased, and the operation time is prolonged. Liquid in the bladder is gradually increased, bladder pressure is increased, the bladder is overfilled, and the bladder function is damaged. According to the scheme, the catheter comprises a guide sheath tube, a bendable catheter is arranged at the front end of the guide sheath tube, a plurality of evenly-distributed second holes are formed in the outer portion, away from the bendable catheter, of the guide sheath tube, and a plurality of evenly-distributed first holes are formed in the outer portion of the front end of the bendable catheter and the outer portion of the front end of the guide sheath tube. Through the arrangement of the first hole and the second hole, liquid in the kidney and the bladder can be further drained out of the body through the liquid passing ability of the measuring holes, the pressure in the kidney and the pressure of the bladder are effectively relieved, and it is ensured that drainage is more sufficient and effective.

The invention provides an SPECT / CT-based renal function determination method and device and a processing system, designs a novel renal function determination architecture, and combines a CT structure image to more accurately distinguish kidney tissues and perirenal tissues and extract more real double-kidney signals compared with a traditional scheme that SPECT images are used for sketching double-kidney ROI (Region of Interest). The high time resolution and the high spatial resolution are both considered, so that the time radioactivity curve and the glomerular filtration rate of the separated kidney can be accurately measured, the high-quality measurement requirement for the separated kidney function in clinical work is met, and high-quality diagnosis and treatment service can be provided for a patient.

Provided herein are perfusion systems (e.g., a perfusion system with an acoustic volume sensor) that deliver a composition comprising at least one agent that induces expression of OCT3 / 4, SOX2, c-MYC, KLF4, N.ANOG, and / or LIN28 in the kidney. Also provided herein are methods and compositions suitable for use with the perfusion systems.

This invention discloses a laparoscopic kidney gripper, comprising a barrel for passing through a laparoscope into the human body and a shell-like body connected thereto; the barrel is retractably fitted with several proximal negative pressure mechanisms and distal traction tubes for adsorbing the kidney; a control mechanism for adjusting the extension and retraction of the traction tubes is installed inside the gun body. Compared to the prior art that uses rigid laparoscopic gastric or intestinal forceps to grip the kidney, this application uses negative pressure suction to form a connection, thereby avoiding slippage and compression damage to the kidney that may occur during clamping connections, thus reducing the difficulty of operation for doctors and the risk of kidney damage to patients.

The invention discloses a Renal scoring method and device for kidney tumors, and belongs to the field of medical image processing. The method comprises the steps that segmentation data are acquired, and the segmentation data comprise data of kidneys, tumors and blood vessels; anatomical analysis is carried out based on the segmentation data, the kidney principal axis, the renal pelvis position and the ureter are determined, and a natural coordinate system of the kidney is established; calculating the maximum diameter of the tumor based on the tumor voxel, and determining an R score according to the maximum diameter of the tumor; constructing a kidney convex hull based on the kidney parenchyma coordinates, and determining an E score based on the proportion of tumor voxels inside and outside the kidney convex hull; taking the ureter as a set system, determining the minimum distance from the tumor voxel to the set system, and determining an N score according to the minimum distance; constructing a natural interface based on the pelvis position, and determining an A score based on the natural interface; detecting polar lines based on the renal door depression, and determining an L score according to the polar lines. The method provided by the invention eliminates the subjective judgment difference of the scorer.

The present application discloses and claims a kidney phantom consisting of a silicone rubber model featuring the anatomical shape of a human kidney, the renal artery, the renal vein, and a total of 11 tumors and 2 cysts. Each tumor is represented by a solid mass, while cysts are empty three-dimensional shapes. In order to accommodate the needs of both novice and advanced surgeons, tumors were designed with increasing surgical difficulty. The kidney phantom disclosed in the present application can be combined with a commercially available ensemble of laparoscopic tools to provide localized and remote training to surgeons and medical staff practicing laparoscopic and robotic partial nephrectomy.

The utility model discloses an anti-reflux ureteral stent, which belongs to the technical field of ureteral stents and comprises a stent pelvis section, a stent ureteral section and a stent bladder section. At least one hollow expansion part is arranged on the tube wall of the bladder section of the stent, and an integrated anti-reflux valve is arranged in a tube cavity of the expansion part. The valve is composed of a plurality of valve-shaped structures, the free ends of the valve-shaped structures can be close to each other to seal a lumen when subjected to retrograde liquid pressure from the bladder to the kidney, the free ends of the valve-shaped structures are separated from each other to open the lumen when subjected to forward liquid pressure from the kidney to the bladder, and therefore one-way drainage of urine is achieved. The anti-backflow urine bag is simple in structure and capable of effectively preventing backflow of urine and complications such as lumbago and hydronephrosis caused by backflow of urine. Meanwhile, due to the structure of the expansion part, the valve can be completely attached to the wall when opened, and operation smoothness and safety are guaranteed when a guide wire is placed in.

A method of treating a renal condition by topical region perfusion of one or both kidneys of a patient is disclosed. A closed circuit is formed with a perfusion catheter positioned in the renal artery of the kidney, a recovery catheter positioned in the renal vein of the kidney, and an extracorporeal membrane oxygenator disposed therebetween. Perfusate containing, for example, a gene therapy drug may circulate through the closed circuit while isolating the closed circuit from the systemic circulation of the patient.

This invention belongs to the field of medical image processing technology, specifically relating to a kidney segmentation method based on key point localization. The method includes the following steps: acquiring medical images of the kidney to be segmented and preprocessing the images; defining a set of anatomical key points specifically for kidney segmentation; predicting the position coordinates of each key point in the key point set using a model; constructing spatial topological relationships between key points based on the predicted key point coordinates and kidney anatomical zoning rules; and dividing the kidney parenchyma into regions according to the spatial topological relationships and kidney anatomical zoning rules, outputting the segmentation results for each kidney segment. This invention achieves efficient and accurate automatic kidney segmentation by precisely detecting anatomical key points and combining them with the anatomical rules of the Graves kidney segment model, outputting segmentation results with anatomical interpretability, and providing reliable technical support for preoperative planning of urological surgeries such as precise nephrectomy.

The invention relates to the technical field of image processing, in particular to a method for evaluating the renal function of a nephrotic patient through diffusion tensor imaging. The method comprises the following steps: acquiring a kidney diffusion tensor original image through single excitation echo plane imaging; adjacent comparison is carried out on each pixel point, and a signal intensity difference and a gradient direction difference are extracted; judging local geometric distortion according to the difference information, and carrying out correction processing pixel by pixel to obtain a corrected high-quality diffusion tensor image; and finally, calculating a fitting tensor, extracting diffusion parameters of the renal cortex and the renal medullary region, quantitatively comparing the diffusion parameters with preset renal function indexes, and outputting an objective quantitative result of the renal function of the patient. According to the method, through pixel-by-pixel distortion correction and direction feature extraction, the precision of the diffusion tensor image and the accuracy of kidney region division are improved, and objective quantitative analysis of kidney functions is realized.

The utility model belongs to the technical field of medical equipment, and provides a home body position calculus removal guiding device which comprises a fixed base, a movable base and a guide rod. The kidney model is arranged on the fixed base, a ureter is arranged on the kidney model, and the kidney model is a transparent material model; a renal pelvis cavity, a kidney large calyx cavity and a kidney small calyx cavity are formed in the kidney model, and the ureter, the renal pelvis cavity, the kidney large calyx cavity and the kidney small calyx cavity are used for simulating the ureter, the renal pelvis, the kidney large calyx and the kidney small calyx of the human kidney respectively. The transparent kidney model is convenient for the patient to intuitively observe the movement track of the stone-like member in the kidney model under different body positions. When the kidney model is used, a patient can wear the kidney model at the preset position of the waist, and the body position is changed according to the dynamic condition of the stone-like piece in the kidney model until the stone-like piece is discharged out of the pelvis. Therefore, the cost of the body position drainage bed for the patient is reduced, the hospital return frequency of the patient is reduced, and the body position calculus removing efficiency of the patient is improved.

The invention discloses a biomarker for detecting renal fibrosis, application and a system, and relates to the technical field of biological medicines. The invention relates to a biomarker for detecting renal fibrosis. The biomarker comprises urinary copper cyanin. Compared with the conventional diagnostic marker (such as eGFR, RBP, NAG and the like), the urocyanin has the following three advantages: 1, compared with the conventional diagnostic marker (such as eGFR, RBP, NAG and the like), the urocyanin is more sensitive to diagnosis of renal interstitial fibrosis and fibrosis severity; secondly, compared with traumatic renal tissue pathologic biopsy, urine is used as a diagnosis medium, so that true noninvasive effect can be realized, and no harm is caused to the body health of a patient; and thirdly, compared with detection means such as iconography, the method for detecting the urinary cupreocyanin marker is lower in cost, more flexible, high in timeliness and easier to popularize.

Systems and methods for renal access and pressure reduction. In one or more embodiments, there are provided various systems and methods to reduce renal pressures. In one or more aspects, there are provided devices and methods for the removal or reduction of a capsular constriction to reduce renal pressures such as by one or more of removing fluid or tissue.

The invention relates to a combined medicine of naltrexone or a structural analogue thereof and a URAT1 inhibitor and application of the combined medicine. The combined medicine can effectively reduce uric acid, treat hyperuricemia and treat renal injury or renal fibrosis. The combined medicine combines different action mechanisms of the two medicines, and can inhibit the activity of xanthine oxidase and reduce reabsorption of renal tubules at the same time, so that uric acid production is reduced, uric acid excretion is increased, and a stronger uric acid reducing effect is expected to be achieved; the damage caused by renal tubule dilatation can be improved, the fibrosis progress is relieved, and then the effect of relieving kidney injury is achieved.

The present invention relates to designed ankyrin repeat domains and designed ankyrin repeat proteins for use in reducing accumulation of a therapeutic and / or diagnostic agent in the kidney of a subject treated with said agent. Preferably such therapeutic and / or diagnostic agent comprises a drug moiety such as a radionuclide or a cytotoxin. In addition, the invention provides recombinant proteins comprising such repeat domains, nucleic acids encoding such repeat domains or recombinant proteins, recombinant expression vectors, host cells, and pharmaceutical compositions comprising such repeat domains, recombinant proteins, nucleic acids or recombinant expression vectors, as well as the use of such repeat domains, recombinant proteins or pharmaceutical compositions in methods for reducing accumulation of a therapeutic and / or diagnostic agent in the kidney of a subject treated with said agent.

The present invention relates to the field of physiotherapy technology, and specifically to a daily hot compress physiotherapy device for the rehabilitation of kidney diseases, comprising: a backrest cushion connected to the seat cushion and a driving member connected to the seat cushion. A chest cushion is further provided on the driving member. When the driving member operates, it can drive the backrest cushion to rotate on the seat cushion, and at the same time drive the chest cushion to rotate and move closer to or away from the seat cushion. Through the design of the adaptive sticking structure, the hot compress physiotherapy device for the rehabilitation of kidney diseases in the present invention realizes the personalization, precision and high efficiency of hot compress treatment; the backrest cushion and chest cushion of the device can flexibly adjust the position and angle according to the patient's body posture and treatment needs, ensuring that the hot compress part is closely attached to the patient's body. The self-conducting mechanism provided on the backrest cushion and chest cushion is only conducted and releases hot compress steam when it comes into contact with the patient's body, avoiding the waste of steam, reducing energy consumption, and further improving the treatment efficiency and the patient's treatment experience.

1. The name of this design product: Kidney Bandage. 2. Purpose of this product design: This product design is used as a special restraint belt for kidney patients. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.

The present application relates to the technical field of kidney function assessment, and particularly relates to a method for assessing the function of each kidney of a child with hydronephrosis based on magnetic resonance images, comprising the following steps: obtaining double-kidney magnetic resonance scanning data of the child with hydronephrosis, and obtaining clinical data and laboratory test data of the child with hydronephrosis; performing kidney region image segmentation and feature extraction in the double-kidney magnetic resonance scanning data to obtain morphological features, omics features and diffusion-weighted features of the hydronephrosis side and the contralateral kidney; and establishing a model for assessing the function of each kidney of the child with hydronephrosis by using the clinical data and the laboratory test data, and the morphological features, the omics features and the diffusion-weighted features of the hydronephrosis side and the contralateral kidney. The present application obtains the imaging data of the magnetic resonance plain scan and diffusion-weighted imaging of the child with hydronephrosis, analyzes the imaging features of each kidney by using an artificial intelligence algorithm, and realizes the assessment of the kidney function by using the analysis results in combination with the imaging features, the clinical biological information and the clinical features of the child.

The invention provides a glomerular filtration rate estimation method and device for a patient with asymmetric double renal functions. The method comprises the following steps: acquiring basic information, clinical data, laboratory detection data and iconography data of a patient, wherein the iconography data comprises kidney volume, blood flow volume, cortex and medullary thickness and kidney function expression of the right kidney and the left kidney; by analyzing iconography data, a functional difference measurement coefficient for quantifying the asymmetry of double kidney functions is calculated. Thirdly, extracting a global feature vector of the patient by using a deep learning model, and performing fusion processing on the iconography data, the clinical data and the laboratory detection data to generate a comprehensive feature vector; and on the basis, the functional weights of the right kidney and the left kidney are adjusted according to the functional difference measurement coefficient, finally, the adjusted functional weights and the global feature vectors are input into a deep regression model, and a corrected GFR estimated value is obtained through calculation. And more accurate renal function evaluation can be provided according to the condition that double renal functions are asymmetric.

This invention relates to the field of pharmaceutical technology, specifically disclosing the application of SRPX2 inhibitors in the preparation of drugs for treating renal fibrosis, including SRPX2 inhibitors. SRPX2 inhibitors regulate the expression of iron metabolism-related proteins by inhibiting the binding of SRPX2 to IRP1, a key regulatory protein in iron metabolism, thereby restoring iron homeostasis and alleviating renal fibrosis. In patients with chronic kidney disease and animal models of renal fibrosis, SRPX2 is highly expressed in renal tubular epithelial cells and is positively correlated with the degree of fibrosis. The use of SRPX2 inhibitors can significantly reduce the pathological changes of renal fibrosis and improve renal function. This invention provides a new treatment strategy and drug candidate for renal fibrosis.

The present invention discloses a method and system for guiding the planning of ablation of a renal lesion, which relates to the technical field of ablation guidance planning. The method and system for guiding the planning of ablation of a renal lesion include the following specific steps: acquiring the anatomical structure of the kidney based on image acquisition, extracting key features from the acquired multi-source images, extracting and identifying the edge of the tumor, identifying the edge of the tumor based on the acquired key features, and generating an optimal ablation path that avoids the key structure. The present invention acquires the anatomical structure of the kidney through multiple CT and ICE images to reduce the error in identifying the boundary of the tumor, and aligns the multi-source images based on a deformation field algorithm to further improve the accuracy of identifying the boundary of the tumor. In the actual ablation process, the multi-source images are fused with an electromagnetic sensor to monitor the deviation of the ablation needle tip.