44 results about "Kidney pelvis" patented technology

There is provided a method for controlling a flow of urine in the urinary passageway of a patient's urethra, ureter, renal pelvis or bladder. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the urinary tissue wall) at least one portion of the urinary tissue wall to influence the flow in the urinary passageway, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the urinary passageway. The method can be used for restricting or stopping the flow in the urinary passageway of a urinary incontinent patient, or for actively moving the urine in the urinary passageway, with a low risk of injuring the urethra, ureter, renal pelvis or bladder.

The present invention provides a novel cancer marker that is useful in the diagnosis of urothelial cancer. The present invention uses ubiquilin 2 as a cancer marker for urothelial cancer (renal pelvis cancer, ureteral cancer, and bladder cancer). Detection of ubiquilin 2 in a urine sample allows easy and accurate diagnosis of a possibility of urothelial cancer. The present invention is also applicable to the diagnosis of squamous cancer (esophageal cancer, cervical cancer, etc.).

The invention relates to a composition for inhibiting or dissolving calcium oxalate stones as well as a preparation method and application of the composition. The composition comprises an immobilizedoxalate decarboxylase that can catalyze a decarboxylation reaction of oxalic acid or / and an oxalate, and the immobilized oxalate decarboxylase is prepared by immobilizing oxalate decarboxylase on a magnetic particle carrier. The composition provided by the invention has the function of inhibiting the growth of the calcium oxalate stones or dissolving the calcium oxalate stones, and has the advantages of mildness, good tolerance and high safety, and a patient has no trauma or pain when the composition is applied to treat kidney stones; and when the composition provided by the invention is applied to treat the calcium oxalate stones, the oxalate decarboxylase can be fixed in a renal pelvis by applying a magnetic field to continuously degrade oxalic acid in urine, so that the action time andefficiency of enzyme are increased, after the treatment is completed, the magnetic field is removed, and immobilized enzyme magnetic beads can be excreted with the urine; and after the composition isused in combination with drugs for regulating the pH of the urine, the effects of degrading the oxalic acid and dissolving the stones can be enhanced.

The invention relates to methods for locally delivering a chemotherapeutic agent to an upper tract urothelial carcinoma (UTUC). The methods involve placing a balloon catheter that has a working channel and a balloon into the ureter / renal pelvis via retrograde or antegrade ureteral access; inflating the catheter balloon to temporarily obstruct the ureter; infusing (instilling) a liposomal formulation that includes a chemotherapeutic agent into the working channel of the catheter; and allowing the infused liposomal formulation to dwell in the ureter and / or renal pelvis for a time sufficient to allow at least a portion of the liposomal formulation to adhere to the urothelial wall. In the methods of the invention, at least a portion of the infused chemotherapeutic-agent formulation adheres tothe urothelial wall while it is instilled and dwells in the ureter and / or renal pelvis. The disclosed methods can be performed as an adjuvant therapy to other methods of treating UTUC, such as ureteroscopic ablation or resection of the tumor.

A ureteral catheter for placement in a kidney, renal pelvis, and / or in a ureter adjacent to the renal pelvis of a patient, includes an elongated tube having a proximal end, a distal end, and a sidewall extending between the proximal end and the distal end of the tube defining at least one drainage lumen extending through the tube; and an expandable retention portion configured to transition from aretracted position to a deployed position and which, in the deployed position, defines a three-dimensional shape positioned to maintain fluid flow from the kidney through at least the distal end of the tube.

There is provided a method for controlling a flow of urine in the urinary passageway of a patient's urethra, ureter, renal pelvis or bladder. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the urinary tissue wall) at least one portion of the urinary tissue wall to influence the flow in the urinary passageway, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the urinary passageway. The method can be used for restricting or stopping the flow in the urinary passageway of a urinary incontinent patient, or for actively moving the urine in the urinary passageway, with a low risk of injuring the urethra, ureter, renal pelvis or bladder.

The invention relates to a ureteral rapid liquid-gas expansion pipeline suite and a using method thereof. The ureteral rapid liquid-gas expansion pipeline suite comprises a first ureteral catheter and a second ureteral catheter. The ureter is pre-expanded through the first ureteral catheter, the first ureteral catheter is not suitable for remaining in the ureter for a long time due to the fact that a pelvis drainage channel is removed from the first ureteral catheter, the problem that the pressure in the kidney of the working side is increased is solved, and therefore the first ureteral catheter is only prepared for short-time expansion and preliminary expansion of the ureter; and after the diameter of the ureter is increased, the second ureteral catheter can be more conveniently placed for long-time expansion, the expansion time is several hours or ten hours or longer, the ureteral expansion effect and safety are greatly improved, the placing success rate of the second ureteral catheter is increased, then the operation success rate of a flexible ureteroscope is increased, the process requirement and price of the flexible ureteroscope are reduced, the performance of the flexible ureteroscope is improved, the diameter of a water flow channel is increased, and the safety and effect of the flexible ureteroscope are rapidly improved.

The invention discloses a ureteral stent special for kidney transplantation. The ureteral stent comprises a stent body, a first curly tube, a tube opening, an intercepting tube, a second curly tube, aguide tube, a bent guide wire, a through hole, a protrusion, an intercepting tube wall, a limiting block, a rubber ring, a round hole, an intercepting cavity, a water blocking ball, a mounting cap and an elastic supporting body. The bent guide wire is made of a plastic material, so that the second coiled tube can be stably fixed in a renal pelvis of a transplanted kidney, the protrusions are allrubber protrusions and can block calculus particles, the stent body is made of a medical silica gel material, the water blocking ball is matched with the round hole, and the stent body is made of a medical silica gel material. The diameter of the water blocking ball is larger than the maximum diameter of the round hole, the phenomenon of urine backflow is prevented conveniently, the smooth layer is arranged in the stent body, a smooth inner surface is provided for the ureteral stent conveniently, smooth passing of fluid is facilitated, and the smoothness of an inner cavity of a tube body of the ureteral stent is improved.

The invention discloses a double-J tube and a preparation method thereof and belongs to a new product obtained through technology improvement and stage change on the basis of a traditional double-J tube. The double-J tube is composed of a pelvis end elastic ring, a bladder end elastic ring and a drainage pipe. The whole double-J tube is formed by connecting catheter ends of materials with different hardnesses. Catheters with different hardnesses are welded and made into novel double-J tubes with different hardnesses, the comfort degree of a patient can be effectively improved after the double-J tube is placed in the body of the patient, pain is relieved, complications are reduced, the life quality of the patient is improved, and the treatment effect is improved.

Drug delivery devices and systems, are provided for delivery of a drug into the upper urinary tract of patients in need thereof. The drug delivery devices (100) may be deployed directly into the renal pelvis via a patient's ureter, bladder, and urethra, and the drug delivery devices can be wholly retained therein for local continuous, controlled release of a drug over an extended period.

The invention relates to the technical field of medical instruments, in particular to a far-end-positioned anti-reflux antibacterial ureter stent tube. The stent tube comprises a hollow catheter and a one-way drainage piece; the hollow catheter is made of flexible materials and can expand in the radial direction of the hollow catheter, and the hollow catheter comprises a pelvis section, a ureter section and a bladder section which are sequentially communicated; the one-way drainage piece is arranged in the bladder section and comprises a one-way opening; when the internal pressure of the ureter section is greater than the pressure of the outer end of the bladder section, the one-way opening is opened; when the internal pressure of the ureter section is less than the pressure of the outer end of the bladder section, the one-way opening is closed, and the pressure needed for opening the one-way opening of the one-way drainage piece is adjustable. By means of the one-way drainage piece capable of guiding urine in the pelvis area to flow towards the bladder area in a one-way mode, the problem of urine backflow is solved, the pressure of the one-way drainage piece for opening the one-way opening can be adjusted according to urination pressure of different patients, filling stimulation is generated on the pelvis area and a ureter cone, creeping of the ureter is obviously enhanced, and the urine backflow rate is reduced.

A pump assembly is provided, including a pump module configured to be positioned within an interior portion of a ureter and / or renal pelvis of a patient for providing negative pressure to the patient's ureter and / or kidney, the pump module including: a housing including a flow channel for conducting fluid, wherein the housing is configured to be positioned within the interior portion of the ureterand / the renal pelvis; and a pump element positioned within the channel to draw fluid through the channel; and a control module coupled to the pump module, the control module being configured to direct motion of the pump element to control flow rate of fluid passing through the channel, and including a housing configured to be positioned within at least one of a second interior portion of the patient's ureter, a second portion of the patient's renal pelvis, or an interior portion of a patient's bladder.

The invention discloses a method for automatically evaluating difficulty of kidney tumor enucleation based on CT (computed tomography) images, which comprises the following steps: based on artificial intelligence and image analysis technologies, segmenting an abdominal wall, a kidney and a kidney tumor at the same time by establishing a deep network model, automatically calculating an MAP score and an R.E.N.A.L score by utilizing relevance among the tumor, a renal pelvis, the kidney and the abdominal wall, and automatically evaluating the difficulty of the kidney tumor enucleation based on the CT images. Therefore, the difficulty of the kidney tumor enucleation is reasonably and effectively evaluated; the method has the advantages of time and labor saving and high evaluation accuracy and reliability.

The invention discloses a ureteral stent tube capable of relieving mucosal lesion. The stent tube is a hollow hose and comprises a tube body, bent sections and blunt thickening sections; the two endsof the tube body are provided with bent sections respectively. The annular diameter of the bent section is smaller, and the bent section is of a disc-shaped structure; the free end of each bent section is provided with a blunt thickening section, the outer diameter of each blunt thickening section is larger than that of each bent section; each blunt thickening section is of a spherical structure,and the end of each blunt thickening section is of a spherical structure, so that a series of side effects can be avoided; the tube body, the bent sections and the blunt thickening sections are identical in inner diameter, and the bent sections and the tube body are identical in outer diameter. According to the invention, tube pushing is not needed, the operation process is simplified, the steps are reduced in the implantation process, and the pain of a patient can be reduced; meanwhile, the two ends of the stent tube are arranged to be of a blunt structure, in the pushing-in process and afterthe stent tube is placed on the human body, stimulation to the renal pelvis and the bladder mucosa can be reduced at the ends, and the phenomena of hematuresis and the like caused by mucous membraneinjury and bleeding are avoided.

The invention discloses a multi-cavity ureter support. The multi-cavity ureter support comprises a first curling section (1), a straight pipe section (2) and a second curling section (3), the straight pipe section (2) includes a first straight pipe (4) and at least one second straight pipe (5), the first straight pipe (4), the first curling section (1) and the second curling section (3) compose a pipe, the second straight pipe (5) is located outside the first straight pipe (4), and the second straight pipe (5) and the first straight pipe (4) are two independent pipes. By means of the multi-cavity ureter support, building of a channel between a bladder and a renal pelvis can be achieved, ureter relevant diseases are treated, and the design of the unique shape helps a doctor to conveniently place and take out the support. By means of the multi-cavity design, the smoothness and safety of the support can be greatly improved, and the effect is more significant for a patient with the support inlay for a long time.

Ureteral bypass devices and procedures for performing internalized urinary diversions within patients. Such a procedure includes implanting a first catheter and securing a distal end of the first catheter within the renal pelvis or ureter of a patient, implanting a cystostomy catheter through and securing a distal end of the cystostomy catheter within the urinary bladder of the patient, fluidically connecting proximal ends of the first and cystostomy catheters to an adapter, and then subcutaneously implanting a sampling / flushing port and fluidically connecting a proximal end of the sampling / flushing port to the adapter via a third catheter to yield an artificial ureteral bypass device, in which the first and cystostomy catheters are fluidically connected together and fluidically connected to the subcutaneously-placed sampling / flushing port.

The invention relates to methods for locally delivering a chemotherapeutic agent to an upper tract urothelial carcinoma (UTUC). The methods involve placing a balloon catheter that has a working channel and a balloon into the ureter / renal pelvis via retrograde or antegrade ureteral access; inflating the catheter balloon to temporarily obstruct the ureter; infusing (instilling) a liposomal formulation that includes a chemotherapeutic agent into the working channel of the catheter; and allowing the infused liposomal formulation to dwell in the ureter and / or renal pelvis for a time sufficient to allow at least a portion of the liposomal formulation to adhere to the urothelial wall. In the methods of the invention, at least a portion of the infused chemotherapeutic-agent formulation adheres to the urothelial wall while it is instilled and dwells in the ureter and / or renal pelvis. The disclosed methods can be performed as an adjuvant therapy to other methods of treating UTUC, such as ureteroscopic ablation or resection of the tumor.

The invention discloses a traditional Chinese medicine composition for treating kidney stone and ureteral stone, which applies the traditional Chinese medicine gasification theory and combines medicines for promoting blood circulation to remove blood stasis and inducing diuresis to achieve the effects of expanding the pelvis, the kidney and the ureter so as to achieve the purposes of removing and dissolving the kidney stone and the ureteral stone; for patients with poor long-term stone removal effects of calcium carbonate and calcium oxalate stones, the stone dissolving effect can be achieved through long-term medicine taking; the effect is fast, the stone removing rate is high, and the side effect is small.

Drug delivery devices and systems, are provided for delivery of a drug into the upper urinary tract of patients in need thereof. The drug delivery devices (100) may be deployed directly into the renal pelvis via a patient's ureter, bladder, and urethra, and the drug delivery devices can be wholly retained therein for local continuous, controlled release of a drug over an extended period.

The invention relates to the technical field of medical instruments, in particular to a capsule ureteroscope and an operation method. The capsule ureteroscope comprises a super-smooth guide wire, a capsule ureteroscope body, a push tube and a monitor. One end of the super-smooth guide wire is arranged in the renal pelvis; the capsule ureteroscope body is arranged at one end of the push tube, and the push tube places the capsule ureteroscope body in the renal pelvis along a channel formed by the super-smooth guide wire in the renal pelvis; and the monitor is arranged on a capsule tube. The operation method comprises the following steps of placing the ultra-smooth guide wire in a ureter under a cystoscope; installing the capsule ureteroscope body along the guide wire; pushing the capsule ureteroscope body into the ureter along the guide wire by the push tube for examination and treatment; after entering the renal pelvis, examining and treating the condition of renal calyx in the renal pelvis by using a remote control technology; and after examination and treatment are completed, pulling out the guide wire and the capsule ureteroscope body from the body together, so that the treatmentprocess is completed. According to the capsule ureteroscope and the operation method, the operation steps are reduced, and the pain of a patient is relieved.

A method for preventing, treating and / or improving a prostatic disease or disorder associated with epithelial hyperplasia and / or fibrosis, comprising: administering an effective amount of a multikinase inhibitor to a subject in need thereof, wherein the multikinase inhibitor has a certain spectrum of kinase inhibitory activity. The multikinase inhibitor is sunitinib, regorafenib, ponatinib, pazopanib, nintedanib and / or lenvatinib. The prostatic disease or disorder is selected from the group consisting of benign prostate hyperplasia and its associated lower urinary tract symptoms, fibrosis of ureters and renal pelvis, prostate adenoma, and prostatic intraepithelial neoplasia in animals and humans.

The invention relates to the technical field of medical instruments, more specifically to a ureteral stent tube. The ureteral stent tube comprises a hollow tube body arranged in the ureter of a patient, a first inserting part arranged in the bladder of the patient and and a second inserting part arranged in the pelvis of the patient, wherein the first inserting part and the second inserting part are respectively arranged at two ends of the hollow tube body and are connected with the hollow tube body through a plurality of connecting pieces; the plurality of connecting pieces are arranged in acircumferential direction of the hollow pipe body at intervals; a urine inlet is arranged between every two adjacent connecting pieces in a spaced mode; an elastic column used for controlling the urine inlet to be opened and closed is arranged at each urine inlet; a sliding block capable of sliding in a length direction of the connecting pieces is arranged among the plurality of connecting pieces;one ends of the elastic columns are connected with and arranged on the hollow tube body; the other ends of the elastic columns are connected with and arranged on the sliding block; and the ureteral stent tube also comprises a control component used for controlling the sliding block to slide. According to a scheme of the invention, the ureteral stent tube has the advantages of reducing stimulationand damage to bladder mucosa, reducing hematuresis and improving comfort of a patient.

The invention discloses a ureteral stent imbedding auxiliary component which comprises a white sheath and a guide sheath movably arranged in the white sheath so as to expand the ureter of a patient and further enable the white sheath to enter the ureter of the patient, an adjustable telescopic mechanism and an adjusting part are arranged in the white sheath, and a protruding part is arranged on the adjustable telescopic mechanism. Compared with the prior art, the ureteral stent imbedding auxiliary component has the advantages that when a surgeon puts in a ureteral stent, it is avoided that blood urine in the pelvis of the patient splashes on the hand after the guide sheath is taken out, the guide sheath is pulled out according to a proper path, and the adjusting part is driven to control the opening of the adjustable telescopic mechanism, so that the blood or urine is prevented from flowing out from the end part of the white sheath, the cleanness of the hands of the surgeon is ensured, and the surgical operation is better carried out; and along with gradual pushing of the white sheath into the body of the patient, an adjusting plate can be driven to be gradually unfolded, so that the blood urine flowing out from the interior of the pelvis can conveniently flow out from the protruding part.

The invention discloses a method of using a ureter double saccule drainage tube. The method comprises the steps that after renal pelvis and renal calyces are dilated through conventional percutaneous hydronephrosis, a guide wire is imported to pass through a ureteral stenosis structure, the ureter double saccule drainage tube is imported through the guide wire; a radiocontrast agent is injected through an external connector of a fork-shaped injection base and is connected with a urine drainage cavity; when the ureteral stenosis structure is at the upper segment of the ureter, the second saccule is located in the ureteral stenosis structure, and the first saccule is located in the ureter; when the ureteral stenosis structure is at the lower segment of the ureter, the first saccule is located in the ureteral stenosis structure, and the second saccule is located in the ureter; the radiocontrast agent is injected through an external connector connected with the first saccule and the external connector connected with the second saccule of the fork-shaped injection base to fill the first saccule and the second saccule; the ureter double saccule drainage tube is fixed on the body surface. The ureter double saccule drainage tube has the advantages of being effective in draining urine, relieving hydronephrosis and expanding continuously the ureteral stenosis structure. The invention also discloses a double saccule drainage tube structure for the method of using the ureter double saccule drainage tube.

Apparatus, systems, and methods for treating PKD by providing access to a patient's renal pelvis of a kidney to treat renal nerves embedded in tissue surrounding the renal pelvis. Access to the renal pelvis may be via the urinary tract or via minimally invasive incisions through the abdomen and kidney tissue. Treatment is effected by exchanging energy, typically delivering heat or extracting heat through a wall of the renal pelvis, or by delivering active substances to ablate a thin layer of tissue lining at least a portion of the renal pelvis to disrupt renal nerves within the tissue lining of the renal pelvis

A pump assembly for increasing the urine output from a patient includes at least one ureteral catheter including a distal portion having a retention portion configured to be positioned in a patient's kidney, renal pelvis, and / or ureter; and a proximal portion defining a drainage lumen. The retention portion includes at least one drainage port which permits fluid flow into the drainage lumen. The pump assembly further includes a pump configured to provide negative pressure to at least one of the renal pelvis or kidney through the drainage lumen of the at least one ureteral catheter. The pump includes at least one fluid port in fluid communication with the drainage lumen of the proximal portion of the ureteral catheter for receiving fluid from the patient's kidney, wherein at least a portion of the pump is configured to be positioned within a patient's body.

The invention relates to a ureter internal drainage device, and belongs to the technical field of medical appliance manufacturing. The ureter internal drainage device comprises a head part, a body part and a tail part, wherein the head part and the tail part are spherical; the drainage pipe and the propeller sleeve the inner sleeve; and the outer sleeve sleeves the drainage pipe and the propeller.The ureter internal drainage device has the beneficial effects that displacement can be prevented, stimulation to the renal pelvis and the bladder is small, and no damage is caused.

The invention discloses a device for calculus irrigation and decompression in ureteroscope lithotripsy. The device comprises a ureteral sheath for constructing an operation channel and a bladder sheath for constructing a decompression channel, wherein a first gap is left between the ureteral sheath and the ureteroscope; and a second gap is left between the ureteral sheath and the ureteroscope. A bladder sheath is arranged outside the ureteral sheath, and the bladder sheath and the ureteral sheath can be slidably and fixedly connected, At that end of the bladder sheath extend into the bladder,One end of the conical tube with a larger outer diameter is connected with the bladder sheath, the inner diameter of the smaller end of the conical tube is adapted to the outer diameter of the ureteral sheath, a through hole penetrating through the wall of the conical tube is arranged on the outer side wall, and a second gap is left between the inner side wall of the bladder sheath and the outer side wall of the ureteral sheath for returning liquid. The device can facilitate the access of the ureteroscope by establishing a fixed operation channel, facilitate the flushing out of the crushed calculus, smooth the fluid return and the decompression of the renal pelvis and bladder.