13 results about "Into ureter" patented technology

The technology described herein is directed to methods of administering a therapeutic composition, such as recombinant adeno-associated virus (rAAV), to a kidney of a subject using a retrograde ureter route, for example, to at least renal papilla of the kidney. Such administration methods can be used to treat a kidney-associated disorder in a subject in need thereof. Also described herein are pharmaceutical compositions comprising a recombinant adeno-associated virus (rAAV) for administration to the kidney.

A urinary system calculus journey explanation model effectively solves the problem of inconvenient use of existing urinary system calculus journey explanation devices; including a support plate, the left and right sides of the front end of the support plate are respectively provided with a renal pelvis model, the front end of the support plate is provided with a bladder model located below the two renal pelvis models, the left and right sides of the front end of the support plate are respectively provided with ureter models located between the renal pelvis models and the bladder model, the upper end of the ureter model is communicated with the corresponding side of the renal pelvis model and the lower end is communicated with the bladder model, the lower end of the bladder model is communicated with a urethra model, a Y-shaped moving groove is opened on the support plate, the renal pelvis model, the ureter model, the bladder model and the urethra model are provided with a communication groove communicated with the moving groove, the left and right sides of the moving groove are respectively provided with front and rear axial sliding columns, and the front end of the sliding column is detachably connected with a calculus model; this structure is simple, novel in design, convenient to use and high in practicality.

The embodiment of the specification provides a ureter tunnel opening system and device based on extensive hysterectomy, and relates to the field of intelligent medical treatment. The system comprises: a surgical field acquisition module configured to acquire a surgical field image after a bladder and bilateral ureters have been dissociated in the implementation of C-type extensive hysterectomy; a tissue structure positioning module configured to position relevant tissue positions according to the surgical field image; a double vertical plane forming module configured to form a vertical plane including a bladder plane perpendicular to a uterine longitudinal axis horizontal plane and a proximal ureter perpendicular to a bladder cervix ligament anterior leaf; a Z-type gap positioning module configured to separate a Z-type gap free of blood vessels; and a tissue resection module configured to open a ureter tunnel, process blood vessels of the ureter tunnel below the ureter, and resect abdominal parametric tissue in a preset range. The application proposes a new gap dissection which can quickly and safely open the ureter tunnel and reduce the risk of ureter injury.

An implantable medical device for use as an artificial urinary bladder can include a collection container configured to be placed in a patient's abdominal cavity and a pump configured to be subcutaneously placed outside the abdominal cavity to allow the patient to perceive the need for urination and controls timing of the urination. Flexible tubing can connect the patient's ureters to the collection container through anti-reflux valves preventing urine from flowing back to kidneys, connect the collection container to the pump through a unidirectional connection valve, and connect the pump to the patient's urethra through a unidirectional urethral valve to allow for urination through the patient's natural urethra.

This invention provides a multi-instrument intelligent collaborative training method based on respiratory motion phase determination, comprising the following steps: constructing a three-dimensional virtual anatomical model including the urethra, bladder, ureter, and kidney, and establishing an interactive connection between the force feedback handle of the simulated surgical instrument and the three-dimensional virtual anatomical model; selecting respiratory samples from a preset database and sending them to the three-dimensional virtual anatomical model, which then simulates the changes in other organs and tissues during lung respiration; collecting kidney motion data from the three-dimensional virtual anatomical model and dividing the kidney motion phase based on the motion data; generating instruction commands based on the kidney motion phase and the surgical instrument, and visually displaying the instruction commands; and having the user perform simulated training through the force feedback handle according to the instruction commands, with reinforcement learning used to optimize the training movements. By introducing kidney motion changes caused by lung respiration, the method can simulate real surgical situations and improve training effectiveness.

The purpose of the present invention is to provide a method for manufacturing a collecting duct of a mature kidney. The purpose of the present invention is also to provide a method for manufacturing a collecting duct organoid of a mature kidney derived from iPSC. According to the present invention, provided is a method for manufacturing a collecting duct of a kidney, the method comprising culturing a ureteric bud in a medium having an isotonic osmotic pressure (iso-osmotic pressure) and then culturing the bud in a medium having one or more osmotic pressures exceeding the iso-osmotic pressure, wherein the medium having at least one osmotic pressure exceeding the iso-osmotic pressure has an osmotic pressure of at least 600 mOsm / kg or greater.

The present disclosure relates to obtaining Foley catheters and double-J catheters that exhibit antibacterial properties and prevent stone formation by means of coating the surfaces of urinary catheters used in the healthcare sector with multiple film layers comprising groups containing gallic acid so as to impart antibacterial properties and stone-formation-preventing effectiveness. It is intended in particular to prevent the ascending transmission of bacteria from the female or male genital region to the bladder with the aid of the catheter during urethral catheter insertion, as well as stone formation due to stasis arising from the slowing of flow and turbulent flow associated with ureteral stents inserted in cases of stricture. It is also intended to prevent the occurrence of damage that may form in the urinary tract due to oxidative stress and inflammation triggered either by infection in the surrounding tissues or by mechanical pressure caused by the stone. Effectiveness is achieved by coating the surfaces of the catheters / stents applied to the urinary tract with film layers of gallic acid, which is effective in all the aforementioned adverse conditions in preventing stone formation and is effective against infectious agents, and which has antioxidant and anti-inflammatory effects.

The application discloses a multifunctional kidney ureteral catheter and relates to the technical field of medical devices; the multifunctional kidney ureteral catheter comprises a ureter, a detection pipeline and a detection device; the pressure sensor cooperates with the valve plate with switchable flow paths, so that the urine flow of the left and right kidneys can be detected at different times and respectively, unilateral kidney function independent monitoring is realized, the real working state of the double kidneys can be accurately reflected, the problem that the traditional mode can only measure the total urine volume and cannot judge unilateral abnormalities is avoided, and when the air bag leaks, the piston in the liquid storage shell can intuitively prompt medical staff and patients through position change, and the air bag inflation can be temporarily supplemented and maintained through normal saline, so that failure early warning is realized, the stent can be prevented from immediately falling off, and the use safety is improved.

A method for preventing and treating internal infections, e.g., urinary tract infections, caused by catheters is provided, in particular by reduction in catheter-associated biofilms. A coating composition is used to treat the catheter and applied through the catheter into the bladder or other body urinary tract organ to kill or neutralize microorganisms, including biofilms therein. The composition comprises a humectant and an antimicrobial with the antimicrobial including a monoquaternary ammonium compound or pharmaceutically acceptable salt thereof. The coating layer has antimicrobial cidal or static activity for at least about one hour.

The technology described herein is directed to methods of administering a therapeutic composition, such as recombinant adeno-associated virus (rAAV), to a kidney of a subject using a retrograde ureter route, for example, to at least renal papilla of the kidney. Such administration methods can be used to treat a kidney-associated disorder in a subject in need thereof. Also described herein are pharmaceutical compositions comprising a recombinant adeno-associated virus (rAAV) for administration to the kidney.

The utility model discloses a kind of balloon catheters for upper urinary tract perfusion, including catheter body and balloon;Catheter body is flexible tubular structure;The inside of catheter body is equipped with perfusion channel and inflation channel, inflation channel is parallel with perfusion channel and is not connected;Annular groove is provided on the outer wall of the proximal end of catheter body, balloon is fixed in annular groove;The front end of inflation channel is communicated with balloon, rear end extends to the outside of catheter body, for inflating balloon;The front end of balloon is trumpet-shaped, rear end gradually narrows, the front end part of balloon after inflation, rear end part respectively adhere to the inner wall of renal pelvis and ureter of upper urinary tract;Several convex points are arranged on the outer wall of the rear end of balloon.The balloon catheter of the utility model can better adhere to the anatomical structure of upper urinary tract, and the positioning effect of balloon catheter is enhanced, to solve the problems in the prior art.