The invention relates to the field of traditional Chinese medicine formulas, in particular to compound herba pyrrosiae desmodium soup for eliminating ureteral calculus. Herba pyrrosiae, desmodium, ventriculi galli mucosa, radices cyathulae, radices paeoniae rubra, radices paeoniae alba, radix glycyrrhizae preparata, dandelion, herba dianthi, pencil stone and torrefied rhubarb are used as raw materials; the ventriculi galli mucosa is smashed; the smashed ventriculi galli mucosa and the herba pyrrosiae, the desmodium, the radices cyathulae, the radices paeoniae rubra, the radices paeoniae alba, the radix glycyrrhizae preparata, the dandelion, the herba dianthi, the pencil stone and the torrefied rhubarb are soaked with water and decocted; and residue is removed to obtain a filtrate so as to prepare the compound herba pyrrosiae desmodium soup. The compound herba pyrrosiae desmodium soup is characterized in that the soup comprises the following raw material compositions in percentage by weight: 5 to 8 percent of the herba pyrrosiae, 15 to 20 percent of the desmodium, 5 to 8 percent of ventriculi galli mucosa, 5 to 8 percent of the radices cyathulae, 8 to 12 percent of the radices paeoniae rubra, 8 to 12 percent of the radices paeoniae alba, 2 to 5 percent of the radix glycyrrhizae preparata, 15 to 20 percent of the dandelion, 5 to 8 percent of the herba dianthi, 10 to 15 percent of the pencil stone and 2 to 5 percent of the torrefied rhubarb. The compound herba pyrrosiae desmodium soup has low cost, high treatment effect of treating ureteral calculus, no toxicity and no side effect, has the functions of diminishing inflammation and resisting infection and is suitable for nephrolith, ureteral calculus, vesical calculus and urethral calculus.