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Application of lobaplatin in preparation of preparation for preventing and treating local middle-and-advanced-stage esophageal cancer radical operation postoperative relapse and metastasis

A technology for recurrence and metastasis, esophageal cancer, applied in the direction of antineoplastic drugs, drug combinations, etc., can solve problems such as poor curative effect, cancer recurrence and metastasis, achieve less adverse reactions, reduce tumor recurrence and metastasis, and have high safety effects

Inactive Publication Date: 2019-05-31
蒋毅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] For this reason, the embodiment of the present invention provides the application of lobaplatin in the preparation of preparations for the prevention and treatment of recurrence and metastasis after radical resection of local advanced esophageal cancer, so as to solve the recurrence and metastasis of cancer prone to occur after the existing esophageal cancer surgery, and the curative effect is insufficient. good question

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  • Application of lobaplatin in preparation of preparation for preventing and treating local middle-and-advanced-stage esophageal cancer radical operation postoperative relapse and metastasis
  • Application of lobaplatin in preparation of preparation for preventing and treating local middle-and-advanced-stage esophageal cancer radical operation postoperative relapse and metastasis
  • Application of lobaplatin in preparation of preparation for preventing and treating local middle-and-advanced-stage esophageal cancer radical operation postoperative relapse and metastasis

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Embodiment

[0023] A clinical trial of applying lobaplatin in radical resection of esophageal cancer to prevent recurrence and metastasis after radical resection of locally advanced esophageal cancer

[0024] 1. General Information

[0025] A total of 80 patients with advanced esophageal squamous cell carcinoma who were treated in our hospital from July 2015 to December 2018 were selected and divided into observation group and control group according to the random number table method, with 40 cases in each group. Among them, the observation group: 13 males and 7 females, aged 54-79 years, with an average age of (66.40±12.60) years. Control group: 14 males and 6 females, aged 54-73 years, with an average age of (63.08±9.02) years. There was no significant difference in gender and age between the two groups (P>0.05). This study was approved by the Ethics Committee of our hospital, and the patients or their close relatives signed an informed consent form for the research protocol.

[0026...

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Abstract

The embodiment of the invention discloses application of lobaplatin in preparation of a preparation for preventing and treating local middle-and-advanced-stage esophageal cancer radical operation postoperative relapse and metastasis, and relates to the technical field of esophageal cancer treatment. Lobaplatin is used for local chemotherapy in the corresponding period in an local middle-and-advanced-stage esophageal cancer radical operation, and the operation and early-stage chemotherapy are organically combined, so that postoperative tumor relapse and metastasis are reduced, the operation curative effect is improved, few adverse reactions are generated, the safety is high, and the lobaplatin is worthy of application and popularization in clinic.

Description

technical field [0001] The embodiment of the present invention relates to the technical field of esophageal cancer treatment, and specifically relates to the application of lobaplatin in the preparation of a preparation for preventing and treating recurrence and metastasis of local middle-advanced esophageal cancer after radical resection. Background technique [0002] Esophageal cancer (EC), also known as esophageal cancer, is one of the common malignant tumors of the digestive tract in humans. It mainly occurs in the esophageal epithelial tissue. The typical symptoms are progressive dysphagia. First, it is difficult to swallow dry food. Then came semi-liquid food, and finally water and saliva could not be swallowed. The incidence of esophageal cancer ranks eighth in the global tumor incidence and sixth in cancer mortality. [0003] my country is a country with a high incidence of esophageal cancer, with an average of about 150,000 deaths per year. Surgery is the main tre...

Claims

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Application Information

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IPC IPC(8): A61K31/555A61P35/00A61P35/04
Inventor 蒋毅程锋
Owner 蒋毅
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