Ercc1 and other markers for stratification of non-small cell lung cancer patients

A non-small cell lung cancer, patient technology, applied in biological testing, analytical materials, instruments, etc., can solve problems such as lack of survival
CN109844539AInactive Publication Date: 2019-06-04NANTOMICS LLC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANTOMICS LLC
Publication Date
2019-06-04
Estimated Expiration
Not applicable · inactive patent

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Abstract

Proteomics data are employed to predict treatment outcome for cisplatin / pemetrexed therapy of NSCLC. Notably, ERRC1 can be used as a binary marker where protein presence or absence is measured by massspectroscopy, and additional proteins may serve as further predictive markers, particularly for prediction of PFS.
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Description

[0001] This application claims priority to U.S. Provisional Application Serial No. 62 / 311368, filed March 21, 2016, and also claims priority to U.S. Provisional Application Serial No. 62 / 337209, filed May 16, 2016; both provisional Both applications are incorporated herein by reference. technical field

[0002] The field of the invention is systems and methods for correlating selected markers with clinical outcomes, particularly with regard to non-small cell lung cancer and ERCC1 status and recurrence-free survival / overall survival. Background technique

[0003] The Background Description includes information useful in understanding the present invention. It is not an admission that any information provided herein is prior art or relevant to the presently claimed invention, or that any publication specifically or implicitly referenced is prior art.

[0004] All publications and patent applications are herein incorporated by reference as if each individual publication or pat...

Claims

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