Liquid chromatography distributor

A technology of liquid chromatography and distributor, which is applied in the direction of solid adsorbent liquid separation, separation methods, chemical instruments and methods, etc., can solve the problems of uneven stress on packing, affecting the uniformity of solution distribution, etc., and improve the uniformity , Improve the uniformity of force and increase the effect of distribution area

Active Publication Date: 2019-07-05
REDPHARM BEIJING BIOPHARMACEUTICAL INST CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At this time, since the liquid chromatography distributor adopts a single-point liquid inlet in the middle, the solution is freely dispersed in the filler centered on the position of the middle hole to the surroundings, so that not only will there be a single point in the vertical section. The pressure peak will make the packing uneven, and there will be channel flow, bias flow, and wall flow, which will affect the uniformity of the solution on the packing surface.

Method used

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Embodiment Construction

[0021] In order to deepen the understanding of the present invention, the present invention will be further described below in conjunction with the embodiments and accompanying drawings. The embodiments are only used to explain the present invention and do not constitute a limitation to the protection scope of the present invention.

[0022] combine Figure 1 to Figure 4 As shown, the liquid chromatography distributor of this embodiment includes an upper distribution plate 1 and a lower distribution plate 2 . The upper distribution plate 1 is provided with a central circular groove 11 and a plurality of distribution grooves 12, wherein the central circular groove 11 is located at the center of the upper distribution plate 1 and communicates with the liquid inlet hole of the column head, and the distribution grooves 12 are along the upper distribution plate. 1 extends in the diameter direction, and a plurality of distribution channels 12 are distributed sequentially along the c...

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Abstract

The present invention relates to a liquid distributor especially suitable for uniformly distributing a liquid, and concretely relates to a liquid chromatography distributor. The liquid chromatographydistributor is disclosed in order to improve the liquid distribution uniformity of the liquid chromatography distributor. The liquid chromatography distributor includes an upper distribution plate anda lower distribution plate; the upper distribution plate is provided with a central circular groove and a plurality of flow dividing grooves, the central circular groove is located at the center position of the upper distribution plate, the flow dividing grooves extend along the diameter direction of the upper distribution plate, the plurality of flow dividing grooves are sequentially distributedalong the circumferential direction, and one end, close to the center position of the upper distribution plate, of every flow dividing groove is communicated with the central circular groove; and thelower distribution plate is provided with a plurality of liquid distribution holes, and the plurality of liquid distribution holes are sequentially distributed along the circumferential direction, and are communicated with the flow dividing grooves. The liquid chromatography distributor can improve the solution distribution uniformity, reduce the phenomena of channeling, bias flow and wall flow and improve the mass transfer efficiency.

Description

technical field [0001] The invention relates to a liquid distribution device, especially suitable for uniform distribution of liquid, in particular to a liquid chromatography distributor. Background technique [0002] The liquid chromatography distributor is one of the most critical components of the liquid chromatography column. It is installed on the upper end of the chromatography column packing and is used to distribute the solution to the surface of the packing to form the initial distribution of the solution. The liquid chromatography distributor directly affects the contact distribution between the solution and the filler, and affects the initial distribution of the solution. Therefore, the liquid distribution effect of the liquid chromatography distributor is very important to the efficiency of liquid mass transfer in the chromatography column. [0003] At present, the most commonly used liquid chromatography distributors in liquid chromatography columns are designed...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D15/14B01D15/22
CPCB01D15/14B01D15/22
Inventor 游可为史国营陆敬坤孙新宇陈浩源
Owner REDPHARM BEIJING BIOPHARMACEUTICAL INST CO LTD
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