Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Biomolecule detection method and device

A technology of biomolecules and detection methods, applied in the field of biomedicine, can solve problems such as long detection time, inability to realize fast real-time detection, complex pre-processing of samples, etc., and achieve the effect of fast real-time detection

Inactive Publication Date: 2019-07-16
NORTH CHINA UNIVERSITY OF TECHNOLOGY
View PDF4 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these detection methods are complex for the pre-processing of the sample, and the analyte needs to be labeled during the detection process, and the experimental operation process is cumbersome.
The most important thing is that its detection time is long, and fast real-time detection cannot be realized

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Biomolecule detection method and device
  • Biomolecule detection method and device
  • Biomolecule detection method and device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention more clear, the embodiments of the present invention will be further described in detail below in conjunction with the accompanying drawings. Here, the exemplary embodiments and descriptions of the present invention are used to explain the present invention, but not to limit the present invention.

[0033] Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings. In the drawings, the same reference numerals represent the same or similar components, or the same or similar steps.

[0034] In the prior art, conventional detection methods for biomolecules such as IL-6 include enzyme-linked immunosorbent assay, fluorescent immunoassay, and chemiluminescence immunoassay. These detection methods need to be labeled during the detection process, and the detection time is relatively long. Long, unable to achieve fast ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a biomolecule detection method and device. The biomolecule detection method comprises the steps that liquid to be detected is added to a nano sensor in covalent linkage with a probe molecule, and the probe molecule can generate specific binding with a biomolecule; under the condition of applying fixed bias on the nano sensor added with the liquid to be detected, first electrical characteristic data of the nano sensor of the liquid to be detected is measured; and comparing the first electrical characteristic data with second electrical characteristic data, whether the biomolecule exists in the liquid to be detected or not is determined, and the second electrical characteristic data is obtained by preloading liquid containing set concentration of biomolecule to the nano sensor covalently linked with the probe molecule and measuring the nano sensor at the fixed bias. The content of the biomolecule is detected through the biomolecule detection method, a target molecule can be prevented from being marked in the detection process, rapid and real-time detection can be realized, and whether the biomolecule is contained or not is determined or the concentration content is measured.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a method and device for detecting biomolecules. Background technique [0002] Malignant tumor is a disease characterized by uncontrolled abnormal proliferation of cells. It is difficult to cure and endangers human health. It has become a major problem in the medical field. Major diseases such as malignant tumors have caused heavy burdens to society and families. However, if the vast majority of tumors can be diagnosed in a timely and efficient manner, early detection and treatment of tumors can be achieved, and the survival rate of patients can be significantly improved. Therefore, the detection of tumor molecular markers for early tumor diagnosis and prognosis assessment has always been a hot spot in the field of laboratory medicine. [0003] Interleukin-6 (IL-6) is a multifunctional cytokine known as a regulator of immune and inflammatory responses. Its overexpression is associate...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N27/26G01N27/00
CPCG01N27/00G01N27/26
Inventor 张楠张静闫江
Owner NORTH CHINA UNIVERSITY OF TECHNOLOGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com