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A strain of Lactobacillus fermentum that can reduce blood uric acid

A technology for fermenting lactobacillus and blood uric acid, applied in the field of microorganisms, can solve problems such as side reactions, liver function damage, allergic reactions, etc., and achieve the effects of inhibiting intake, reducing uric acid levels, and reducing blood uric acid levels.

Active Publication Date: 2020-12-08
HANGZHOU WAHAHA TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, most drugs have side effects of varying degrees, such as severe allergic reactions, gastrointestinal reactions, bone marrow suppression, liver function damage, etc.

Method used

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  • A strain of Lactobacillus fermentum that can reduce blood uric acid
  • A strain of Lactobacillus fermentum that can reduce blood uric acid
  • A strain of Lactobacillus fermentum that can reduce blood uric acid

Examples

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Embodiment 1

[0027] Example A strain of Lactobacillus fermentum that can reduce blood uric acid was obtained from traditional yogurt collected near Alashankou in Xinjiang Uygur Autonomous Region of China in the previous work of the inventor. It was identified as Lactobacillus fermentum and named as 2644 strain. It was preserved in the General Microorganism Culture Collection Center of China Microbiology Culture Collection Management Committee on November 19, 2018. The microorganism preservation number is CGMCC NO.16754. The biological properties of the strain are as follows:

[0028] Morphological characteristics: In MRS agar medium, the growth form is milky white colony, opaque, round, smooth and moist surface, neat edges, and raised in the center. Gram staining was typically positive, and under the microscope the cells were short rod-shaped, without flagella, non-spore-forming, and non-moving ( Figure 1-2 shown).

[0029] Culture characteristics: The optimum growth temperature is 37°C...

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Abstract

The invention relates to the field of microorganisms, and discloses a strain of Lactobacillus fermentum that can reduce blood uric acid. The strain is named: 2644 strain, which was preserved in the General Microbial Strain Preservation Center of the China Microbial Strain Collection Management Committee on November 19, 2018. Microbial The deposit number is CGMCC NO.16754; the address of the depository unit is No. 3, Yard No. 1, Beichen West Road, Chaoyang District, Beijing, and the microbial classification is named Lactobacillus fermentum . The bacterial strain of the invention can effectively reduce the content of blood uric acid. In addition to reducing the intake of exogenous purine substances, it can also promote the excretion of uric acid in the body from the intestines, and more effectively control the body's blood uric acid level.

Description

technical field [0001] The invention relates to the field of microorganisms, in particular to a lactobacillus fermentum capable of reducing blood uric acid. Background technique [0002] Clinically, hyperuricemia can be diagnosed when the blood uric acid level of men is greater than 7.0 mg / dL and that of women is greater than 6.0 mg / dL. According to statistics, the prevalence of hyperuricemia in the general population in my country is about 10%, which is comparable to the prevalence of diabetes; while the prevalence of hyperuricemia in coastal and economically developed areas is above 20%. The 2017 China Gout Status Survey shows that the number of patients with hyperuricemia in my country has reached 170 million. Gout has become the second largest metabolic disease in my country after diabetes. [0003] The amount of uric acid in the circulating blood is mainly determined by the dynamic relationship between the synthesis and excretion of uric acid in the human body. The s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20A23L33/135A61K35/747A61P19/06C12R1/225
CPCA23L33/135A61K35/747A61P19/06A23V2002/00C12R2001/225C12N1/205A23V2400/143A23V2200/30
Inventor 朱珺孙盛李言郡陈作国陈苏任学良姜雄韬
Owner HANGZHOU WAHAHA TECH
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