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A preparation method of a Tibetan traditional Chinese medicine composition for treating liver diseases, the composition and granules containing it

The technology of a composition and granules is applied in the field of preparation of Tibetan traditional Chinese medicine compositions, which can solve the problems of low content of active ingredients, large dosage, difficult absorption, etc., and achieves few added types, long application time, and reduced irritation and toxic and side effects. Effect

Active Publication Date: 2021-05-04
西藏藏医药大学
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Aiming at the problems of the existing classic Tibetan medicine Qiwei Honghua Zhusheng Pills, such as low active ingredient content, difficult absorption, large dosage, high nephrotoxicity, and difficult storage, the present invention provides a preparation method of a Tibetan traditional Chinese medicine composition for treating liver diseases, The composition and granules containing it

Method used

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  • A preparation method of a Tibetan traditional Chinese medicine composition for treating liver diseases, the composition and granules containing it

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Embodiment 1

[0033] A preparation method of a Tibetan traditional Chinese medicine composition for treating liver diseases, comprising the following process steps:

[0034] Mix the woody Aristolochia and honey in a mass ratio of 3:1, mix well, let stand for 10 minutes, heat at 110°C for 1 hour, repeat the above process 3 times, and let it cool for later use; weigh 700g of safflower, 500g of Tianzhuhuang , 500g Ephedra, 500g Swertia clam, 500g processed Aristolochia aristolochia, 500g Meconopsis five veins and 600g Myrobalan mix to obtain the mixture of medicine, add 15.2kg of 20vt% ethanol solution in the mixture respectively and 1.9kg of 2vt% acetic acid solution, heated to 60°C, refluxed for 2h, separated the medicinal residues to obtain extract I; then added 11.4kg of 20vt% ethanol solution and 1.4kg of 2vt% acetic acid to the medicinal residues solution, heated to 60°C, refluxed for extraction for 2 hours, and the medicinal residues were separated to obtain the extract II; the extract ...

Embodiment 2

[0039] A preparation method of a Tibetan traditional Chinese medicine composition for treating liver diseases, comprising the following process steps:

[0040] Mix the woody Aristolochia and honey in a mass ratio of 4:1, mix evenly, let stand for 15 minutes, heat at 115°C for 1.5 hours, repeat the above process 3 times, and let it cool for later use; weigh 700g of safflower, 600g of Tianzhu Huang, 600g Ephedra, 600g Swertia bruceae, 600g processed Aristolochia spp., 600g Meconopsis quinquefolium and 700g Myrobalan are mixed to obtain a drug mixture, and 22kg of 23vt% ethanol solution is added to the mixture respectively and 2.2kg of 3vt% acetic acid solution, heated to 70°C, refluxed and extracted for 1.5h, separated the medicinal residues to obtain extract I; then added 17.6kg of 23vt% ethanol solution and 1.8kg of 3vt% ethanol solution to the medicinal residues Acetic acid solution, heating to 70°C, reflux extraction for 1.5h, separating medicinal residues to obtain extract ...

Embodiment 3

[0045] A preparation method of a Tibetan traditional Chinese medicine composition for treating liver diseases, comprising the following process steps:

[0046] Mix the woody Aristolochia and honey in a mass ratio of 3:1, mix evenly, let stand for 10 minutes, heat at 115°C for 1.5 hours, repeat the above process 4 times, and let it cool for later use; weigh 800g of safflower, 600g of Tianzhu Huang, 600g Ephedra, 500g Swertia bruceae, 500g processed Aristolochia spp., 500g Meconopsis quincescens and 700g Myrobalan are mixed to obtain a drug mixture, and 25.2kg of 25vt% ethanol is added to the mixture respectively Solution and 2.6kg of 5vt% acetic acid solution, heated to 80°C, refluxed for 1h, and the medicinal residues were separated to obtain extract I; then 21kg of 25vt% ethanol solution and 2.1kg of 5vt% acetic acid were added to the medicinal residues solution, heated to 80° C., refluxed for extraction for 1 hour, and the medicinal residues were separated to obtain extract ...

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Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, and specifically discloses a preparation method of a Tibetan traditional Chinese medicine composition for treating liver diseases. Meconopsis and Myrobalan are mixed to obtain a mixture, 20-25vt% ethanol solution and 2-5vt% acetic acid solution are respectively added to the mixture, heated and refluxed for extraction, and an extract containing the Tibetan traditional Chinese medicine composition is obtained, wherein the The volume ratio of ethanol solution and acetic acid solution is 8-10:1. The Tibetan traditional Chinese medicine of the invention has a simple preparation method and few types of auxiliary materials, can significantly improve symptoms such as liver blood hyperplasia caused by old and new liver diseases and overwork, is applicable to a wide range of clinical populations, has good curative effect, and has no adverse reactions.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a preparation method of a Tibetan traditional Chinese medicine composition for treating liver diseases, the composition and granules containing the same. Background technique [0002] Qiwei Honghua Zhusheng Pill is a classic prescription of Tibetan medicine for the treatment of icteric hepatitis. This product was first recorded in the 8th century A.D. Tibetan medical classic medical work "Sibu Medical Code". Doll and Meconopsis have the effects of clearing heat and detoxification, clearing liver and cooling blood, promoting blood circulation and benefiting lungs, Tianzhu Huang clears lung heat; Myrobalan can not only reconcile the properties of medicine, but also reconcile the three causes, so it can treat the diseases caused by new and old liver diseases. Hepatic blood hyperplasia, hepatomegaly, sclera staining yellow, loss of appetite, etc. ha...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/899A61K47/69A61P1/16A61P35/00
CPCA61K9/1652A61K36/17A61K36/185A61K36/264A61K36/286A61K36/51A61K36/66A61K36/899A61K2236/333A61K2236/39A61K47/6951A61P1/16A61P35/00A61K2300/00
Inventor 吴宗耀张巍央美蒋士卿银政冯彩霞魏丹丹朱星昊朱守强
Owner 西藏藏医药大学
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